Free Access
Issue
Med Sci (Paris)
Volume 27, Number 11, Novembre 2011
Page(s) 993 - 999
Section M/S Revues
DOI https://doi.org/10.1051/medsci/20112711016
Published online 30 November 2011
  1. Xu H, Barnes GT, Yang Q, et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003 ; 112 : 1821–1830. [CrossRef] [PubMed] [Google Scholar]
  2. Weisberg SP, McCann D, Desai M, et al. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003 ; 112 : 1796–1808. [CrossRef] [PubMed] [Google Scholar]
  3. Cinti S, Mitchell G, Barbatelli G, et al. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 2005 ; 46 : 2347–2355. [CrossRef] [PubMed] [Google Scholar]
  4. Shi H, Kokoeva MV, Inouye K, et al. TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 2006 ; 116 : 3015–3025. [CrossRef] [PubMed] [Google Scholar]
  5. Suganami T, Yuan X, Shimoda Y, et al. Activating transcription factor 3 constitutes a negative feedback mechanism that attenuates saturated fatty acid/toll-like receptor 4 signaling and macrophage activation in obese adipose tissue. Circ Res 2009 ; 105 : 25–32. [CrossRef] [PubMed] [Google Scholar]
  6. Kopp A, Bala M, Buechler C, et al. C1q/TNF-related protein-3 represents a novel and endogenous lipopolysaccharide antagonist of the adipose tissue. Endocrinology 2010 ; 151 : 5267–5278. [CrossRef] [PubMed] [Google Scholar]
  7. Oh da Y, Talukdar S, Bae EJ, et al. GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell 2010 ; 142 : 687–698. [CrossRef] [PubMed] [Google Scholar]
  8. Ye J. Emerging role of adipose tissue hypoxia in obesity and insulin resistance. Int J Obes (Lond) 2009 ; 33 : 54–66. [CrossRef] [PubMed] [Google Scholar]
  9. Elgazar-Carmon V, Rudich A, Hadad N, Levy R. Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding. J Lipid Res 2008 ; 49 : 1894–1903. [CrossRef] [PubMed] [Google Scholar]
  10. Ohmura K, Ishimori N, Ohmura Y, et al.Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice. Arterioscler Thromb Vasc Biol 2010 ; 30 : 193–199. [CrossRef] [PubMed] [Google Scholar]
  11. Liu J, Divoux A, Sun J, et al. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med 2009 ; 15 : 940–945. [CrossRef] [PubMed] [Google Scholar]
  12. Kintscher U, Hartge M, Hess K, et al. T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance. Arterioscler Thromb Vasc Biol 2008 ; 28 : 1304–1310. [CrossRef] [PubMed] [Google Scholar]
  13. Nishimura S, Manabe I, Nagasaki M, et al. CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 2009 ; 15 : 914–920. [CrossRef] [PubMed] [Google Scholar]
  14. Winer S, Chan Y, Paltser G, et al. Normalization of obesity-associated insulin resistance through immunotherapy. Nat Med 2009 ; 15 : 921–929. [CrossRef] [PubMed] [Google Scholar]
  15. Feuerer M, Herrero L, Cipolletta D, et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 2009 ; 15 : 930–939. [CrossRef] [PubMed] [Google Scholar]
  16. Duffaut C, Zakaroff-Girard A, Bourlier V, et al. Interplay between human adipocytes and T lymphocytes in obesity: CCL20 as an adipochemokine and T lymphocytes as lipogenic modulators. Arterioscler Thromb Vasc Biol 2009 ; 29 : 1608–1614. [CrossRef] [PubMed] [Google Scholar]
  17. Lumeng CN, Deyoung SM, Bodzin JL, Saltiel AR. Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity. Diabetes 2007 ; 56 : 16–23. [CrossRef] [PubMed] [Google Scholar]
  18. Tsou CL, Peters W, Si Y, et al. Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. J Clin Invest 2007 ; 117 : 902–909. [CrossRef] [PubMed] [Google Scholar]
  19. Westcott DJ, Delproposto JB, Geletka LM, et al. MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity. J Exp Med 2009 ; 206 : 3143–3156. [CrossRef] [PubMed] [Google Scholar]
  20. Ghanim H, Aljada A, Hofmeyer D, et al. Circulating mononuclear cells in the obese are in a proinflammatory state. Circulation 2004 ; 110 : 1564–1571. [CrossRef] [PubMed] [Google Scholar]
  21. Rogacev KS, Ulrich C, Blomer L, et al. Monocyte heterogeneity in obesity and subclinical atherosclerosis. Eur Heart J 2010 ; 31 : 369–376. [CrossRef] [PubMed] [Google Scholar]
  22. Sell H, Eckel J. Monocyte chemotactic protein-1 and its role in insulin resistance. Curr Opin Lipidol 2007 ; 18 : 258–262. [CrossRef] [PubMed] [Google Scholar]
  23. Curat CA, Miranville A, Sengenes C, et al. From blood monocytes to adipose tissue-resident macrophages: induction of diapedesis by human mature adipocytes. Diabetes 2004 ; 53 : 1285–1292. [CrossRef] [PubMed] [Google Scholar]
  24. Keophiphath M, Rouault C, Divoux A, et al. CCL5 promotes macrophage recruitment and survival in human adipose tissue. Arterioscler Thromb Vasc Biol 2010 ; 30 : 39–45. [CrossRef] [PubMed] [Google Scholar]
  25. Villaret A, Galitzky J, Decaunes P, et al. Adipose tissue endothelial cells from obese human subjects: differences among depots in angiogenic, metabolic, and inflammatory gene expression and cellular senescence. Diabetes 2010 ; 59 : 2755–2763. [CrossRef] [PubMed] [Google Scholar]
  26. Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 2007 ; 117 : 175–184. [CrossRef] [PubMed] [Google Scholar]
  27. Fujisaka S, Usui I, Bukhari A, et al. Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice. Diabetes 2009 ; 58 : 2574–2582. [CrossRef] [PubMed] [Google Scholar]
  28. Strissel KJ, Stancheva Z, Miyoshi H, et al. Adipocyte death, adipose tissue remodeling, and obesity complications. Diabetes 2007 ; 56 : 2910–2918. [CrossRef] [PubMed] [Google Scholar]
  29. Shaul ME, Bennett G, Strissel KJ, et al. Dynamic, M2-like remodeling phenotypes of CD11c+ adipose tissue macrophages during high-fat diet : induced obesity in mice. Diabetes 2010 ; 59 : 1171–1181. [CrossRef] [PubMed] [Google Scholar]
  30. Zeyda M, Farmer D, Todoric J, et al. Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production. Int J Obes (Lond) 2007 ; 31 : 1420–1428. [CrossRef] [PubMed] [Google Scholar]
  31. Bourlier V, Zakaroff-Girard A, Miranville A, et al. Remodeling phenotype of human subcutaneous adipose tissue macrophages. Circulation 2008 ; 117 : 806–815. [CrossRef] [PubMed] [Google Scholar]
  32. Aron-Wisnewsky J, Tordjman J, Poitou C, et al. Human adipose tissue macrophages: m1 and m2 cell surface markers in subcutaneous and omental depots and after weight loss. J Clin Endocrinol Metab 2009 ; 94 : 4619–4623. [CrossRef] [PubMed] [Google Scholar]
  33. Wentworth JM, Naselli G, Brown WA, et al. Pro-inflammatory CD11c+CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity. Diabetes 2010 ; 59 : 1648–1656. [CrossRef] [PubMed] [Google Scholar]
  34. Spencer M, Yao-Borengasser A, Unal R, et al. Adipose tissue macrophages in insulin resistant subjects are associated with collagen VI, fibrosis and demonstrate alternative activation. Am J Physiol Endocrinol Metab 2010 ; 299 : E1016–E1027. [CrossRef] [PubMed] [Google Scholar]
  35. Ichioka M, Suganami T, Tsuda N, et al. Increased expression of macrophage-inducible C-type lectin in adipose tissue of obese mice and humans. Diabetes 2011 ; 60 : 819–826. [CrossRef] [PubMed] [Google Scholar]
  36. Prieur X, Mok CY, Velagapudi VR, et al. Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and m2/m1 polarization in obese mice. Diabetes 2011 ; 60 : 797–809. [CrossRef] [PubMed] [Google Scholar]
  37. Koliwad SK, Streeper RS, Monetti M, et al. DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation. J Clin Invest 2010 ; 120 : 756–767. [CrossRef] [PubMed] [Google Scholar]
  38. Harman-Boehm I, Bluher M, Redel H, et al. Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesity. J Clin Endocrinol Metab 2007 ; 92 : 2240–2247. [CrossRef] [PubMed] [Google Scholar]
  39. Apovian CM, Bigornia S, Mott M, et al. Adipose macrophage infiltration is associated with insulin resistance and vascular endothelial dysfunction in obese subjects. Arterioscler Thromb Vasc Biol 2008 ; 28 : 1654–1659. [CrossRef] [PubMed] [Google Scholar]
  40. Tordjman J, Poitou C, Hugol D, et al. Association between omental adipose tissue macrophages and liver histopathology in morbid obesity: influence of glycemic status. J Hepatol 2009 ; 51 : 354–362. [CrossRef] [PubMed] [Google Scholar]
  41. Kosteli A, Sugaru E, Haemmerle G, et al. Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue. J Clin Invest 2010 ; 120 : 3466–3479. [CrossRef] [PubMed] [Google Scholar]
  42. Divoux A, Tordjman J, Lacasa D, et al. Fibrosis in human adipose tissue: composition, distribution, and link with lipid metabolism and fat mass loss. Diabetes 2010 ; 59 : 2817–2825. [CrossRef] [PubMed] [Google Scholar]
  43. Keophiphath M, Achard V, Henegar C, et al. Macrophage-secreted factors promote a profibrotic phenotype in human preadipocytes. Mol Endocrinol 2009 ; 23 : 11–24. [CrossRef] [PubMed] [Google Scholar]
  44. Foufelle F, Ferré P. La réponse UPR : son rôle physiologique et physiopathologique. Med Sci (Paris) 2007 ; 23 : 291–296. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  45. Migdal C, Serres M. Espèces réactives de l’oxygène et stress oxydant. Med Sci (Paris) 2011 ; 27 : 405–412. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  46. Mege JL, Capo C. La polarisation des macrophages, le nœud gordien des infections bactériennes ? Med Sci (Paris) 2010 ; 26 : 83–88. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.