Free Access
Issue
Med Sci (Paris)
Volume 19, Number 8-9, Août-Septembre 2003
Page(s) 854 - 859
Section M/S Revues
DOI https://doi.org/10.1051/medsci/20031989854
Published online 15 August 2003
  1. Fajans SS, Bell GI, Polonsky KS. Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. N Engl J Med 2001; 345 : 971–80. [Google Scholar]
  2. Timsit J, Dubois-Laforgue D, Boitard C, Bellané- Chantelot C, Velho G. Physiopathologie, présentation clinique et complications des diabètes de type MODY. In: Actualités néphrologiques. Paris: Flammarion Médecine-Sciences, 2002: 89–98. [Google Scholar]
  3. Velho G, Froguel P, Clément K, et al. Primary pancreatic beta-cell secretory defect caused by mutations in the glucokinase in kindreds of maturity onset diabetes of the young. Lancet 1992; 340: 444–8. [Google Scholar]
  4. Byrne MM, Sturis J, Clément K, et al. Insulin secretory abnormalities in subjects with hyperglycemia due to glucokinase mutations. J Clin Invest 1994; 93: 1120–30. [Google Scholar]
  5. Velho G, Petersen KF, Perseghin G, et al. Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects. J Clin Invest 1996; 98: 1755–61. [Google Scholar]
  6. Hattersley AT, Beards F, Ballantyne E, et al. Mutations in the glucokinase gene of the fetus result in reduced birth weight. Nat Genet 1998; 19: 268–70. [Google Scholar]
  7. Velho G, Blanché H, Vaxillaire M, et al. Identification of 14 new glucokinase mutations and description of the clinical profile of 42 MODY-2 families. Diabetologia 1997; 40: 217–24. [Google Scholar]
  8. Pearson ER, Velho G, Clark P, et al. β-cell genes and diabetes: quantitative and qualitative differences in the pathophysiology of hepatic nuclear factor 1- alpha and glucokinase mutations. Diabetes 2001; 50 (suppl 1): S101–7. [Google Scholar]
  9. Velho G, Vaxillaire M, Boccio V, Charpentier G, Froguel P. Diabetes complications in NIDDM kindreds linked to the MODY-3 locus on chromosome 12q. Diabetes Care 1996; 19: 915–9. [Google Scholar]
  10. Byrne MM, Sturis J, Menzel S, et al. Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes mellitus susceptibility gene MODY on chromosome 12. Diabetes 1996; 45: 1503- 10. [Google Scholar]
  11. Pontoglio M, Sreenan S, Roe M, et al. Defective insulin secretion in hepatocyte nuclear factor 1-α deficient mice. J Clin Invest 1998; 101: 2215–22. [Google Scholar]
  12. Dukes ID, Sreenan S, Roe MW, et al. Defective pancreatic b-cell glycolytic signaling in Hepatocyte Nuclear Factor-1α- deficient mice. J Biol Chem 1998; 273: 24457–64. [Google Scholar]
  13. Vaxillaire M, Abderrahmani A, Boutin P, et al. Anatomy of a homeoprotein revealed by the analysis of human MODY3 mutations. J Biol Chem 1999; 274: 35639–46. [Google Scholar]
  14. Pontoglio M, Prié D, Cheret C, et al. HNF-1α controls renal glucose reabsorption in mouse and man. EMBO Rep 2000; 1: 359–65. [Google Scholar]
  15. Isomaa B, Henricsson M, Lehto M, et al. Chronic diabetic complications in patients with MODY3 diabetes. Diabetologia 1998; 41: 467–73. [Google Scholar]
  16. Stoffel M, Duncan SA. The maturity-onset diabetes of the young (MODY1) transcription factor HNF4 alpha regulates expression of genes required for glucose transport and metabolism. Proc Natl Acad Sci USA 1997; 94: 13209–14. [Google Scholar]
  17. Thomas H, Jaschkowitz K, Bulman M, et al. A distant upstream promoter of the HNF-4alpha gene connects the transcription factors involved in maturity-onset diabetes of the young. Hum Mol Genet 2001; 10: 2089–97. [Google Scholar]
  18. Shih DQ, Screenan S, Munoz KN, et al. Loss of HNF-1 alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism. Diabetes 2001; 50: 2472–80. [Google Scholar]
  19. Lindner TH, Njolstad PR, Horikawa Y, et al. A novel syndrome of diabetes mellitus, renal dysfunction and genital malformation associated with a partial deletion of the pseudo-POU domain of hepatocyte nuclear factor-1 beta. Hum Mol Genet 1999; 8: 2001–8. [Google Scholar]
  20. Stoffers DA, Ferrer J, Clarke WL, Habener JF. Early-onset type 2 diabetes mellitus (MODY4) linked to IPF1. Nat Genet 1997; 17: 138–9. [Google Scholar]

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