Figure 2.
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Schéma simplifié de la cascade de signalisation dépendant de l’activation de la voie de signalisation AKT/mTOR. PI3K : phosphoinositide 3-kinase ; AKT : protéine kinase B ; GBL : G protein beta subunit-like ; S6K1 : S6 kinase 1 ; 4EBPA : eukaryotic translation initiation factor 4E-binding protein 1; mLST8 : mTOR-associated protein, LST8 homolog ; PKA : protéine kinase A ; mTOR : mammalian target of rapamycin.
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