Open Access
Med Sci (Paris)
Volume 37, Number 2, Février 2021
Page(s) 152 - 158
Section M/S Revues
Published online 16 February 2021
  1. Guénet JL, Panthier JJ, Avner P, et al. L’héritage de Mary F. Lyon (1925–2014). Med Sci (Paris) 2015 ; 31 : 687–689. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  2. Chu C, Zhang QC, da Rocha ST, et al. Systematic discovery of Xist RNA binding proteins. Cell 2015 ; 161 : 404–416. [CrossRef] [PubMed] [Google Scholar]
  3. McHugh CA, Chen CK, Chow A, et al. The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3. Nature 2015 ; 521 : 232–236. [CrossRef] [PubMed] [Google Scholar]
  4. Minajigi A, Froberg J, Wei C, et al. Chromosomes. A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation. Science 2015; 349 : 10.1126/science.aab2276 aab2276. [Google Scholar]
  5. Monfort A, Di Minin G, Postlmayr A, et al. Identification of spen as a crucial factor for Xist function through forward genetic screening in haploid embryonic stem cells. Cell Rep 2015 ; 12 : 554–561. [CrossRef] [PubMed] [Google Scholar]
  6. Dossin F, Pinheiro I, Żylicz JJ, et al. SPEN integrates transcriptional and epigenetic control of X-inactivation. Nature 2020; 578 : 455–60. [CrossRef] [PubMed] [Google Scholar]
  7. Żylicz JJ, Bousard A, Žumer K, et al. The implication of early chromatin changes in X chromosome inactivation. Cell 2019; 176 : 182–97.e23. [CrossRef] [PubMed] [Google Scholar]
  8. Bousard A, Raposo AC, Żylicz JJ, et al. The role of Xist-mediated Polycomb recruitment in the initiation of X-chromosome inactivation. EMBO Rep 2019 ; 20 : e48019. [CrossRef] [PubMed] [Google Scholar]
  9. Pintacuda G, Wei G, Roustan C, et al. hnRNPK recruits PCGF3/5-PRC1 to the Xist RNA B-repeat to establish polycomb-mediated chromosomal silencing. Mol Cell 2017 ; 68 : 955–969 e10. [Google Scholar]
  10. Almeida M, Pintacuda G, Masui O, et al. PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation. Science 2017 ; 356 : 1081–1084. [Google Scholar]
  11. Gendrel AV, Apedaile A, Coker H, et al. Smchd1-dependent and independent pathways determine developmental dynamics of Cpg island methylation on the inactive X chromosome. Dev Cell 2012 ; 23 : 265–279. [CrossRef] [PubMed] [Google Scholar]
  12. Gdula MR, Nesterova TB, Pintacuda G, et al. The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome. Nat Commun 2019 ; 10 : 30. [Google Scholar]
  13. Chen CK, Blanco M, Jackson C, et al. Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing. Science 2016 ; 354 : 468–472. [Google Scholar]
  14. Nesterova TB, Wei G, Coker H, et al. Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation. Nat Commun 2019 ; 10 : 1–15. [Google Scholar]
  15. Jeon Y, Lee JT. YY1 Tethers Xist RNA to the inactive X nucleation center. Cell 2011 ; 146 : 119–133. [CrossRef] [PubMed] [Google Scholar]
  16. Yamada N, Hasegawa Y, Yue M, et al. Xist exon 7 contributes to the stable localization of Xist RNA on the inactive X-chromosome. PLoS Genet 2015 ; 11 : e1005430. [CrossRef] [PubMed] [Google Scholar]
  17. Marahrens Y, Panning B, Dausman J, et al. Xist-deficient mice are defective in dosage compensation but not spermatogenesis. Genes Dev 1997 ; 11 : 156–166. [CrossRef] [PubMed] [Google Scholar]
  18. Czermin΄ski JT, Lawrence JB. Silencing trisomy 21 with XIST in neural stem cells promotes neuronal differentiation. Dev Cell 2020; 52 : 294–308.e3. [CrossRef] [PubMed] [Google Scholar]
  19. Wutz A, Jaenisch R. A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation. Mol Cell 2000 ; 5 : 695–705. [CrossRef] [PubMed] [Google Scholar]
  20. Briggs SF, Dominguez AA, Chavez SL, et al. Single-cell XIST expression in human preimplantation embryos and newly reprogrammed female induced pluripotent stem cells: XIST in human preimplantation embryos and iPSCs. Stem Cells 2015 ; 33 : 1771–1781. [CrossRef] [PubMed] [Google Scholar]
  21. Okamoto I, Patrat C, Thépot D, et al. Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development. Nature 2011 ; 472 : 370–374. [CrossRef] [PubMed] [Google Scholar]
  22. Petropoulos S, Edsgärd D, Reinius B, et al. Single-cell RNA-Seq reveals lineage and X chromosome dynamics in human preimplantation embryos. Cell 2016 ; 165 : 1012–1026. [CrossRef] [PubMed] [Google Scholar]
  23. Vallot C, Patrat C, Collier AJ, et al. XACT noncoding RNA competes with XIST in the control of X chromosome activity during human early development. Cell Stem Cell 2017 ; 20 : 102–111. [Google Scholar]
  24. Moreira de Mello JC, Fernandes GR, Vibranovski MD, et al. Early X chromosome inactivation during human preimplantation development revealed by single-cell RNA-sequencing. Sci Rep 2017 ; 7 : 1–12. [CrossRef] [PubMed] [Google Scholar]
  25. Zhou F, Wang R, Yuan P, et al. Reconstituting the transcriptome and DNA methylome landscapes of human implantation. Nature 2019 ; 572 : 660–664. [CrossRef] [PubMed] [Google Scholar]
  26. Vallot C, Rougeulle C. Inactivation du chromosome X chez l’humain: XACT et XIST, à chacun son chromosome. Med Sci (Paris) 2013 ; 29 : 223–225. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  27. Vallot C, Huret C, Lesecque Y, et al. XACT, a long noncoding transcript coating the active X chromosome in human pluripotent cells. Nat Genet 2013 ; 45 : 239–241. [Google Scholar]
  28. Casanova M, Moscatelli M, Chauvière LÉ, et al. A primate-specific retroviral enhancer wires the XACT lncRNA into the core pluripotency network in humans. Nat Commun 2019 ; 10 : 5652. [Google Scholar]
  29. Csankovszki G, Panning B, Bates B, et al. Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation. Nat Genet 1999 ; 22 : 323–324. [Google Scholar]
  30. Carrel L, Brown CJ. When the Lyon(ized chromosome) roars: ongoing expression from an inactive X chromosome. Philos Trans R Soc Lond B Biol Sci 2017 ; 372 : [Google Scholar]
  31. Libert C, Dejager L, Pinheiro I. The X chromosome in immune functions: when a chromosome makes the difference. Nat Rev Immunol 2010 ; 10 : 594–604. [CrossRef] [PubMed] [Google Scholar]
  32. Syrett CM, Anguera MC. When the balance is broken: X-linked gene dosage from two X chromosomes and female-biased autoimmunity. J Leukoc Biol 2019 ; 106 : 919–932. [Google Scholar]
  33. Souyris M, Cenac C, Azar P, et al. TLR7 escapes X chromosome inactivation in immune cells. Sci Immunol 2018; 3 : eaap8855. [CrossRef] [PubMed] [Google Scholar]
  34. Souyris M, Mejía JE, Chaumeil J, et al. Female predisposition to TLR7-driven autoimmunity: gene dosage and the escape from X chromosome inactivation. Semin Immunopathol 2019 ; 41 : 153–164. [Google Scholar]
  35. Chaligné R, Popova T, Mendoza-Parra M-A, et al. The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer. Genome Res 2015 ; 25 : 488–503. [CrossRef] [PubMed] [Google Scholar]
  36. Sirchia SM, Tabano S, Monti L, et al. Misbehaviour of XIST RNA in breast cancer cells. PLoS One 2009 ; 4 : e5559. [Google Scholar]
  37. Kawakami T, Zhang C, Taniguchi T, et al. Characterization of loss-of-inactive X in Klinefelter syndrome and female-derived cancer cells. Oncogene 2004 ; 23 : 6163–6169. [Google Scholar]
  38. Yildirim E, Kirby JE, Brown DE, et al. Xist RNA is a potent suppressor of hematologic cancer in mice. Cell 2013 ; 152 : 727–742. [CrossRef] [PubMed] [Google Scholar]
  39. Fang H, Disteche CM, Berletch JB. X Inactivation and escape: epigenetic and structural features. Front Cell Dev Biol 2019 ; 7 : 219. [CrossRef] [PubMed] [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.