Tableau II.
Protéines identifiées comme partenaires des protéines impliquées dans les maladies par expansion de polyglutamine [4, 40].
HAP1 : huntingtin-associated protein 1 ; HIP : huntingtin-interacting protein ; HYP : huntingtin-yeast partner ; CBS : cystathionine β-synthase ; SH3GL3 : SH3 containing Grb2-like protein; N-CoR: nuclear receptor corepressor ; CBP: CREB-binding protein ; MLK2 : mixed-lineage kinase 2 ; LANP: leucine-rich acidic nuclear protein ; A1Up : ataxin-1 interacting protein (ubiquitin-like nuclear protein) ; A2BP1 : ataxin-2 binding protein 1 ; hHR23A/B : human homologs of RAD23; SH3P12GP: SH3P12 gene product ; AIP: atrophin-binding protein ; RERE : arginine-glutamate repeat protein ; IRSp53 : insulin receptor tyrosine kinase substrate protein of 53kDa ; PQBP-1 : polyQ tract-binding domain protein ; polyQ: polyglutamine; GAPDH : glycéraldéhyde-3 phosphate déshydrogénase; SH3: Src homology 3 ; UBL: ubiquitin-like.
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