Peut-on séparer GVH et GVT après greffe de cellules souches hématopoïétiques allogéniques ?

Mohamad Mohty; Daniel Olive

doi:10.1051/medsci/2003195540

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Volume 19 / Numéro 5 (Mai 2003)

Med Sci (Paris), 19 5 (2003) 540-541

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Numéro		Med Sci (Paris) Volume 19, Numéro 5, Mai 2003


Page(s)		540 - 541
Section		Le Magazine : Nouvelles
DOI		https://doi.org/10.1051/medsci/2003195540
Publié en ligne		15 mai 2003

Horowitz MM, Gale RP, Sondel PM, et al. Graft- versus - leukemia reactions after bone marrow transplantation. Blood 1990; 75: 555–62. [Google Scholar]
Weiden PL, Sullivan KM, Flournoy N, Storb R, Thomas ED. Antileukemic effect of chronic graft-versus -host disease: contribution to improved survival after allogeneic marrow transplantation. N Engl J Med 1981; 304: 1529–33. [Google Scholar]
Maraninchi D, Gluckman E, Blaise D, et al. Impact of Tcell depletion on outcome of allogeneic bone-marrow transplantation for standard-risk leukaemias. Lancet 1987; 2: 175–8. [Google Scholar]
Kolb HJ, Schattenberg A, Goldman JM, et al. Graft- versus - leukemia effect of donor lymphocyte transfusions in marrow grafted patients. European group for blood and marrow transplantation working party chronic leukemia. Blood 1995; 86: 2041–50. [Google Scholar]
Falkenburg, JH, Wafelman AR, Joosten P, et al. Complete remission of accelerated phase chronic myeloid leukemia by treatment with leukemiareactive cytotoxic T lymphocytes. Blood 1999; 94: 1201–8. [Google Scholar]
Michalek, J, Collins RH, Durrani HP, et al. Definitive separation of graft-versus leukemia- and graft-versus host- specific CD4+ T cells by virtue of their receptor beta loci sequences. Proc Natl Acad Sci USA 2003; 100: 1180–4. [Google Scholar]
Childs, R, Chernoff A, Contentin N, et al. Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation. N Engl J Med 2000; 343: 750–8 [Google Scholar]

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[1] Horowitz MM, Gale RP, Sondel PM, et al. Graft- versus - leukemia reactions after bone marrow transplantation. Blood 1990; 75: 555–62. [Google Scholar]

[2] Weiden PL, Sullivan KM, Flournoy N, Storb R, Thomas ED. Antileukemic effect of chronic graft-versus -host disease: contribution to improved survival after allogeneic marrow transplantation. N Engl J Med 1981; 304: 1529–33. [Google Scholar]

[3] Maraninchi D, Gluckman E, Blaise D, et al. Impact of Tcell depletion on outcome of allogeneic bone-marrow transplantation for standard-risk leukaemias. Lancet 1987; 2: 175–8. [Google Scholar]

[4] Kolb HJ, Schattenberg A, Goldman JM, et al. Graft- versus - leukemia effect of donor lymphocyte transfusions in marrow grafted patients. European group for blood and marrow transplantation working party chronic leukemia. Blood 1995; 86: 2041–50. [Google Scholar]

[5] Falkenburg, JH, Wafelman AR, Joosten P, et al. Complete remission of accelerated phase chronic myeloid leukemia by treatment with leukemiareactive cytotoxic T lymphocytes. Blood 1999; 94: 1201–8. [Google Scholar]

[6] Michalek, J, Collins RH, Durrani HP, et al. Definitive separation of graft-versus leukemia- and graft-versus host- specific CD4+ T cells by virtue of their receptor beta loci sequences. Proc Natl Acad Sci USA 2003; 100: 1180–4. [Google Scholar]

[7] Childs, R, Chernoff A, Contentin N, et al. Regression of metastatic renal-cell carcinoma after nonmyeloablative allogeneic peripheral-blood stem-cell transplantation. N Engl J Med 2000; 343: 750–8 [Google Scholar]