Accès gratuit
Med Sci (Paris)
Volume 19, Numéro 3, Mars 2003
Page(s) 345 - 350
Section M/S Revues
Publié en ligne 15 mars 2003
  1. Blackburn EH. Switching and signaling at the telomere. Cell 2001; 106: 661–73.
  2. Bryan TM, Cech TR. Telomerase and the maintenance of chromosome ends. Curr Opin Cell Biol 1999; 11: 318–24.
  3. Hayflick L, Moorhead PS. The limited in vitro lifetime of human diploid cell strains. Exp Cell Res 1961; 25: 585–621.
  4. Harley CB, Vaziri H, Counter CM, Allsopp RC. The telomere hypothesis of cellular aging. Exp Gerontol 1992; 27: 375–82.
  5. Chiu CP, Harley CB. Replicative senescence and cell immortality: the role of telomeres and telomerase. Proc Soc Exp Biol Med 1997; 214: 99–106.
  6. Kim NW, Piatyszek MA, Prowse KR, et al. Specific association of human telomerase activity with immortal cells and cancer. Science 1994; 266: 2011–5.
  7. Holt SE, Shay JW. Role of telomerase in cellular proliferation and cancer. J Cell Physiol 1999; 180: 10–8.
  8. Jiang XR, Jimenez G, Chang E, et al. Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nat Genet 1999; 21: 111–4.
  9. Wright WE, Shay JW. Cellular senescence as a tumorprotection mechanism: the essential role of counting. Curr Opin Genet Dev 2001; 11: 98–103.
  10. Cerottini JC, MacDonald HR. The cellular basis of T-cell memory. Annu Rev Immunol 1989; 7: 77–89.
  11. Brummendorf TH, Lansdorp PM, Rufer N. Telomere length dynamic in normal and malignant hematopoiesis. J Anti-Aging Med 2000; 3: 395–407.
  12. Weng NP, Hathcock KS, Hodes RJ. Regulation of telomere length and telomerase in T and B cells: a mechanism for maintaining replicative potential. Immunity 1998; 9: 151–7.
  13. Rufer N, Brümmendorf TH, Kolvraa S, et al. Telomere fluorescence measurements in granulocytes and T lymphocytes subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood. J Exp Med 1999; 2: 157–67.
  14. Broccoli D, Young JW, de Lange T. Telomerase activity in normal and malignant hematopoietic cells. Proc Natl Acad Sci USA 1995; 92: 9082–6.
  15. Weng NP. Regulation of telomerase expression in human lymphocytes. Springer Semin Immunopathol 2002; 24: 23–33.
  16. Maini MK, Soares MV, Zilch CF, Akbar AN, Beverley PC. Virus-induced CD8+ T cell clonal expansion is associated with telomerase up-regulation and telomere length preservation: a mechanism for rescue from replicative senescence. J Immunol 1999; 162: 4521–6.
  17. Weng NP, Palmer LD, Levine BL, Lane HC, June CH, Hodes RJ. Tales of tails: regulation of telomere length and telomerase activity during lymphocyte development, differentiation, activation, and aging. Immunol Rev 1997; 160: 43–54.
  18. Effros RB, Pawelec G. Replicative senescence of T cells: does the Hayflick limit lead to immune exhaustion? Immunol Today 1997; 18: 450–4.
  19. Rufer N, Migliaccio M, Antonchuk J, Humphries RK, Roosnek E, Lansdorp PM. Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential. Blood 2001; 98: 597–603.
  20. Migliaccio M, Amacker M, Just T, et al. Ectopic human telomerase catalytic subunit expression maintains telomere length but is not sufficient for CD8+ T lymphocyte immortalization. J Immunol 2000; 165: 4978–84.
  21. Hooijberg E, Ruizendaal JJ, Snijders PJF, Kueter EWM, Walboomers JMM, Spits H. Immortalization of human CD8+ T cell clones by ectopic expression of telomerase reverse transcriptase. J Immunol 2000; 165: 4239–45.
  22. Rosenberg SA. Progress in human tumour immunology and immunotherapy. Nature 2001; 411: 380–4.
  23. Lansdorp PM, Verwoerd NP, Vanderijke FM, et al. Heterogeneity in telomere length of human chromosomes. Hum Mol Genet 1996; 5: 685–91.

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