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Home All issues Volume 40 / No 2 (Février 2024) Med Sci (Paris), 40 2 (2024) 167-175 References
Open Access
Issue
Med Sci (Paris)
Volume 40, Number 2, Février 2024
Page(s) 167 - 175
Section M/S Revues
DOI https://doi.org/10.1051/medsci/2023220
Published online 27 February 2024
  1. Weil R, Laplantine E, Curic S, Genin P. Role of Optineurin in the Mitochondrial Dysfunction : Potential Implications in Neurodegenerative Diseases and Cancer. Front Immunol 2018 ; 9 : 1243. [CrossRef] [PubMed] [Google Scholar]
  2. Lopez-Domenech G, Kittler JT. Mitochondrial regulation of local supply of energy in neurons. Curr Opin Neurobiol 2023; 81 : 102 747. [Google Scholar]
  3. Chen W, Zhao H, Li Y. Mitochondrial dynamics in health and disease : mechanisms and potential targets. Signal Transduct Target Ther 2023; 8 : 333. [CrossRef] [PubMed] [Google Scholar]
  4. Rangaraju V, Lauterbach M, Schuman EM. Spatially Stable Mitochondrial Compartments Fuel Local Translation during Plasticity. Cell 2019 ; 176(73–84): e15. [CrossRef] [PubMed] [Google Scholar]
  5. Van Laar VS, Arnold B, Howlett EH, et al. Evidence for Compartmentalized Axonal Mitochondrial Biogenesis : Mitochondrial DNA Replication Increases in Distal Axons As an Early Response to Parkinson’s Disease-Relevant Stress. J Neurosci 2018 ; 38 : 7505–7515. [CrossRef] [PubMed] [Google Scholar]
  6. Lu D, Feng Y, Liu G, et al. Mitochondrial transport in neurons and evidence for its involvement in acute neurological disorders. Front Neurosci 2023; 17 : 1 268 883. [CrossRef] [Google Scholar]
  7. Huang N, Li S, Xie Y, et al. Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia. Curr Biol 2021; 31 : 3098–114 e7. [CrossRef] [PubMed] [Google Scholar]
  8. Misgeld T, Schwarz TL. Mitostasis in Neurons : Maintaining Mitochondria in an Extended Cellular Architecture. Neuron 2017 ; 96 : 651–666. [CrossRef] [PubMed] [Google Scholar]
  9. Bock FJ, Tait SWG. Mitochondria as multifaceted regulators of cell death. Nat Rev Mol Cell Biol 2020; 21 : 85–100. [CrossRef] [PubMed] [Google Scholar]
  10. Xu Y, Shen J, Ran Z. Emerging views of mitophagy in immunity and autoimmune diseases. Autophagy 2020; 16 : 3–17. [CrossRef] [PubMed] [Google Scholar]
  11. Yu J, Nagasu H, Murakami T, et al. Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy. Proc Natl Acad Sci U S A 2014 ; 111 : 15514–519. [Google Scholar]
  12. Albensi BC. What Is Nuclear Factor Kappa B (NF-kappaB) Doing in and to the Mitochondrion ?. Front Cell Dev Biol 2019 ; 7 : 154. [CrossRef] [PubMed] [Google Scholar]
  13. Harding O, Holzer E, Riley JF, et al. Damaged mitochondria recruit the effector NEMO to activate NF-kappaB signaling. Mol Cell 2023; 83 : 3188–204 e7. [CrossRef] [PubMed] [Google Scholar]
  14. Uoselis L, Nguyen TN, Lazarou M. Mitochondrial degradation : Mitophagy and beyond. Mol Cell 2023; 83 : 3404–20. [CrossRef] [PubMed] [Google Scholar]
  15. Moore AS, Holzbaur EL. Spatiotemporal dynamics of autophagy receptors in selective mitophagy. Autophagy 2016 ; 12 : 1956–1957. [CrossRef] [PubMed] [Google Scholar]
  16. Yamano K, Kikuchi R, Kojima W, et al. Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy. J Cell Biol 2020; 219. [Google Scholar]
  17. Nguyen TN, Sawa-Makarska J, Khuu G, et al. Unconventional initiation of PINK1/Parkin mitophagy by Optineurin. Mol Cell 2023; 83 : 1693–709 e9. [CrossRef] [PubMed] [Google Scholar]
  18. Allingham RR, Liu Y, Rhee DJ. The genetics of primary open-angle glaucoma : a review. Exp Eye Res 2009 ; 88 : 837–844. [CrossRef] [PubMed] [Google Scholar]
  19. Liu Y, Allingham RR. Molecular genetics in glaucoma. Exp Eye Res 2011 ; 93 : 331–339. [CrossRef] [PubMed] [Google Scholar]
  20. Sirohi K, Kumari A, Radha V, Swarup G. A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin. PLoS One 2015 ; 10 : e0138289. [CrossRef] [PubMed] [Google Scholar]
  21. Zhang S, Shao Z, Liu X, et al. The E50K optineurin mutation impacts autophagy-mediated degradation of TDP-43 and leads to RGC apoptosis in vivo and in vitro. Cell Death Discov 2021; 7 : 49. [CrossRef] [PubMed] [Google Scholar]
  22. Liu X, Hou M, Zhang S, et al. Neuroprotective effects of bone marrow Sca-1 (+) cells against age-related retinal degeneration in OPTN E50K mice. Cell Death Dis 2021; 12 : 613. [CrossRef] [PubMed] [Google Scholar]
  23. Liu X, Wang Q, Shao Z, et al. Proteomic analysis of aged and OPTN E50K retina in the development of normal tension glaucoma. Hum Mol Genet 2021; 30 : 1030–44. [CrossRef] [PubMed] [Google Scholar]
  24. Sirohi K, Swarup G. Defects in autophagy caused by glaucoma-associated mutations in optineurin. Exp Eye Res 2016 ; 144 : 54–63. [CrossRef] [PubMed] [Google Scholar]
  25. Jeong Y, Davis CO, Muscarella AM, et al. Glaucoma-associated Optineurin mutations increase transmitophagy in a vertebrate optic nerve. bioRxiv 2023 May 30 : 2023.05.26.542507. doi : 10.1101/2023.05.26.542507. [PubMed] [Google Scholar]
  26. Hou M, Shao Z, Zhang S, et al. Age-related visual impairments and retinal ganglion cells axonal degeneration in a mouse model harboring OPTN (E50K) mutation. Cell Death Dis 2022; 13 : 362. [CrossRef] [PubMed] [Google Scholar]
  27. Sirohi K, Chalasani ML, Sudhakar C, et al. M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells. Autophagy 2013 ; 9 : 510–527. [CrossRef] [PubMed] [Google Scholar]
  28. Nagabhushana A, Bansal M, Swarup G. Optineurin is required for CYLD-dependent inhibition of TNFalpha-induced NF-kappaB activation. PLoS One 2011 ; 6 : e17477. [CrossRef] [PubMed] [Google Scholar]
  29. Medchalmi S, Tare P, Sayyad Z, Swarup G. A glaucoma- and ALS-associated mutant of OPTN induces neuronal cell death dependent on Tbk1 activity, autophagy and ER stress. FEBS J 2021; 288 : 4576–95. [CrossRef] [PubMed] [Google Scholar]
  30. Neumann M, Sampathu DM, Kwong LK, et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 2006 ; 314 : 130–133. [CrossRef] [PubMed] [Google Scholar]
  31. Chu CT. Mechanisms of selective autophagy and mitophagy : Implications for neurodegenerative diseases. Neurobiol Dis 2019 ; 122 : 23–34. [CrossRef] [PubMed] [Google Scholar]
  32. Li YR, King OD, Shorter J, Gitler AD. Stress granules as crucibles of ALS pathogenesis. J Cell Biol 2013 ; 201 : 361–372. [CrossRef] [PubMed] [Google Scholar]
  33. Kwiatkowski TJ, Jr., Bosco DA, Leclerc AL, et al. Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science 2009 ; 323 : 1205–1208. [CrossRef] [PubMed] [Google Scholar]
  34. Pottier C, Rampersaud E, Baker M, et al. Identification of compound heterozygous variants in OPTN in an ALS-FTD patient from the CReATe consortium : a case report. Amyotroph Lateral Scler Frontotemporal Degener 2018 ; 19 : 469–471. [CrossRef] [PubMed] [Google Scholar]
  35. Nakazawa S, Oikawa D, Ishii R, et al. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nat Commun 2016 ; 7(12): 547. [Google Scholar]
  36. Moore AS, Holzbaur EL. Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy. Proc Natl Acad Sci U S A 2016 ; 113 : E3349–E3358. [PubMed] [Google Scholar]
  37. Hu WB, et al. Neutralizing peripheral circulating IL1beta slows the progression of ALS in a lentivirus-infected OPTN (E478G) mouse model. Animal Model Exp Med 2023; 6 : 18–25. [CrossRef] [PubMed] [Google Scholar]
  38. Mohovic N, Peradinovic J, Markovinovic A, et al. Neuroimmune characterization of optineurin insufficiency mouse model during ageing. Sci Rep 2023; 13 : 11840. [CrossRef] [PubMed] [Google Scholar]
  39. Kakihana T, Takahashi M, Katsuragi Y, et al. The optineurin/TIA1 pathway inhibits aberrant stress granule formation and reduces ubiquitinated TDP-43. iScience 2021; 24 : 102 733. [Google Scholar]
  40. Mou Y, Li M, Liu M, et al. OPTN variants in ALS cases : a case report of a novel mutation and literature review. Neurol Sci 2022; 43 : 5391–6. [CrossRef] [PubMed] [Google Scholar]
  41. Deng H, Wang P, Jankovic J. The genetics of Parkinson disease. Ageing Res Rev 2018 ; 42 : 72–85. [CrossRef] [PubMed] [Google Scholar]
  42. Dominguez J, Yu JT, Tan YJ, et al. Novel Optineurin Frameshift Insertion in a Family With Frontotemporal Dementia and Parkinsonism Without Amyotrophic Lateral Sclerosis. Front Neurol 2021; 12 : 645 913. [CrossRef] [Google Scholar]
  43. Imberechts D, Kinnart I, Wauters F, et al. DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy. Brain 2022; 145 : 4368–84. [CrossRef] [PubMed] [Google Scholar]
  44. Tanner CM, Kamel F, Ross GW, et al. Rotenone, paraquat, and Parkinson’s disease. Environ Health Perspect 2011 ; 119 : 866–872. [CrossRef] [PubMed] [Google Scholar]
  45. Wise JP, Jr., Cannon J. From the Cover : Alterations in Optineurin Expression and Localization in Pre-clinical Parkinson’s Disease Models. Toxicol Sci 2016 ; 153 : 372–381. [CrossRef] [PubMed] [Google Scholar]
  46. Schwab C, Yu S, McGeer EG, McGeer PL. Optineurin in Huntington’s disease intranuclear inclusions. Neurosci Lett 2012 ; 506 : 149–154. [CrossRef] [PubMed] [Google Scholar]
  47. Sahlender DA, Roberts RC, Arden SD, et al. Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis. J Cell Biol 2005 ; 169 : 285–295. [CrossRef] [PubMed] [Google Scholar]
  48. Moharir SC, Raghawan AK, Ramaswamy R, Swarup G. Autophagy-independent cytoprotection by optineurin from toxicity of aggregates formed by mutant huntingtin and mutant ataxin-3. J Biochem 2022; 171 : 555–65. [CrossRef] [PubMed] [Google Scholar]
  49. Osawa T, Mizuno Y, Fujita Y, et al. Optineurin in neurodegenerative diseases. Neuropathology 2011 ; 31 : 569–574. [CrossRef] [PubMed] [Google Scholar]
  50. Xu Y, Liu Y, Chen X, et al. OPTN attenuates the neurotoxicity of abnormal Tau protein by restoring autophagy. Transl Psychiatry 2022; 12 : 230. [CrossRef] [PubMed] [Google Scholar]
  51. Roca-Agujetas V, Barbero-Camps E, de Dios C, et al. Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer’s disease. Mol Neurodegener 2021; 16 : 15. [CrossRef] [PubMed] [Google Scholar]
  52. Du F, Yu Q, Yan S, et al. PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer’s disease. Brain 2017 ; 140 : 3233–3251. [CrossRef] [PubMed] [Google Scholar]
  53. Duan R, Hong CG, Chen ML, et al. Targeting autophagy receptors OPTN and SQSTM1 as a novel therapeutic strategy for osteoporosis complicated with Alzheimer’s disease. Chem Biol Interact 2023; 377 : 110 462. [Google Scholar]
  54. Kruppa AJ, Kishi-Itakura C, Masters TA, et al. Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria. Dev Cell 2018 ; 44 : 484–99.e6. [CrossRef] [PubMed] [Google Scholar]

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