Free Access
Issue
Med Sci (Paris)
Volume 33, Number 3, Mars 2017
Autophagie
Page(s) 268 - 274
Section M/S Revues
DOI https://doi.org/10.1051/medsci/20173303013
Published online 03 April 2017
  1. Cambridge SB, Gnad F, Nguyen C, et al. Systems-wide proteomic analysis in mammalian cells reveals conserved, functional protein turnover. J Proteome Res 2011 ; 10 : 5275–5284. [CrossRef] [Google Scholar]
  2. Martinez-Vicente M, Vila M. Alpha-synuclein and protein degradation pathways in Parkinson’s disease: a pathological feed-back loop. Exp Neurol 2013 ; 247 : 308–313. [CrossRef] [PubMed] [Google Scholar]
  3. Wong E, Cuervo AM. Autophagy gone awry in neurodegenerative diseases. Nat Neurosci 2010 ; 13 : 805–811. [CrossRef] [PubMed] [Google Scholar]
  4. Bourdenx M, Dehay B. What lysosomes actually tell us about Parkinson’s disease? Ageing Res Rev 2016 ; 32 : 140–149. [CrossRef] [PubMed] [Google Scholar]
  5. Yamamoto A, Yue Z. Autophagy and its normal and pathogenic states in the brain. Annu Rev Neurosci 2014 ; 37 : 55–78. [CrossRef] [Google Scholar]
  6. Magrassi L, Leto K, Rossi F. Lifespan of neurons is uncoupled from organismal lifespan. Proc Natl Acad Sci USA 2013 ; 110 : 4374–4379. [CrossRef] [Google Scholar]
  7. Allen NJ, Barres BA. Neuroscience. Glia: more than just brain glue. Nature 2009 ; 457 : 675–677. [CrossRef] [PubMed] [Google Scholar]
  8. Pfrieger FW, Reber M. Un nouvel aperçu des mécanismes de la communication neurone-glie. Med Sci (Paris) 2013 ; 29 : 142–144. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  9. Matthews MR, Raisman G. A light and electron microscopic study of the cellular response to axonal injury in the superior cervical ganglion of the rat. Proc R Soc Lond B Biol Sci 1972 ; 181 : 43–79. [CrossRef] [PubMed] [Google Scholar]
  10. Broadwell RD, Cataldo AM. The neuronal endoplasmic reticulum: its cytochemistry and contribution to the endomembrane system. II. Axons and terminals. J Comp Neurol 1984 ; 230 : 231–248. [CrossRef] [Google Scholar]
  11. Hernandez D, Torres CA, Setlik W, et al. Regulation of presynaptic neurotransmission by macroautophagy. Neuron 2012 ; 74 : 277–284. [CrossRef] [Google Scholar]
  12. Shehata M, Matsumura H, Okubo-Suzuki R, et al. Neuronal stimulation induces autophagy in hippocampal neurons that is involved in AMPA receptor degradation after chemical long-term depression. J Neurosci 2012 ; 32 : 10413–10422. [CrossRef] [PubMed] [Google Scholar]
  13. Janen SB, Chaachouay H, Richter-Landsberg C. Autophagy is activated by proteasomal inhibition and involved in aggresome clearance in cultured astrocytes. Glia 2010 ; 58 : 1766–1774. [CrossRef] [PubMed] [Google Scholar]
  14. Tydlacka S, Wang CE, Wang X, et al. Differential activities of the ubiquitin-proteasome system in neurons versus glia may account for the preferential accumulation of misfolded proteins in neurons. J Neurosci 2008 ; 28 : 13285–13295. [CrossRef] [PubMed] [Google Scholar]
  15. Puyal J, Ginet V, Vaslin A, et al. Les deux visages de l’autophagie dans le système nerveux. Med Sci (Paris) 2009 ; 25 : 383–390. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  16. Jellinger KA. Recent advances in our understanding of neurodegeneration. J Neural Transm (Vienna) 2009 ; 116 : 1111–1162. [CrossRef] [PubMed] [Google Scholar]
  17. Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008 ; 132 : 27–42. [CrossRef] [PubMed] [Google Scholar]
  18. Nixon RA, Wegiel J, Kumar A, et al. Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study. J Neuropathol Exp Neurol 2005 ; 64 : 113–122. [CrossRef] [PubMed] [Google Scholar]
  19. Dehay B, Bove J, Rodriguez-Muela N, et al. Pathogenic lysosomal depletion in Parkinson’s disease. J Neurosci 2010 ; 30 : 12535–12544. [CrossRef] [PubMed] [Google Scholar]
  20. Li X, Alafuzoff I, Soininen H, et al. Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer’s disease brain. FEBS J 2005 ; 272 : 4211–4220. [CrossRef] [PubMed] [Google Scholar]
  21. Pickford F, Masliah E, Britschgi M, et al. The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. J Clin Invest 2008 ; 118 : 2190–2199. [PubMed] [Google Scholar]
  22. Nixon RA. Autophagy, amyloidogenesis and Alzheimer disease. J Cell Sci 2007 ; 120 : 4081–4091. [CrossRef] [PubMed] [Google Scholar]
  23. Dehay B, Bourdenx M, Gorry P, et al. Targeting alpha-synuclein for treatment of Parkinson’s disease: mechanistic and therapeutic considerations. Lancet Neurol 2015 ; 14 : 855–866. [CrossRef] [PubMed] [Google Scholar]
  24. Cuervo AM, Stefanis L, Fredenburg R, et al. Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science 2004 ; 305 : 1292–1295. [CrossRef] [PubMed] [Google Scholar]
  25. Wang Y, Martinez-Vicente M, Kruger U, et al. Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing. Hum Mol Genet 2009 ; 18 : 4153–4170. [CrossRef] [PubMed] [Google Scholar]
  26. Mattson MP, Magnus T. Ageing and neuronal vulnerability. Nat Rev Neurosci 2006 ; 7 : 278–294. [CrossRef] [Google Scholar]
  27. Ben-Zvi A, Miller EA, Morimoto RI. Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging. Proc Natl Acad Sci USA 2009 ; 106 : 14914–14919. [CrossRef] [Google Scholar]
  28. Cuervo AM, Dice JF. Age-related decline in chaperone-mediated autophagy. J Biol Chem 2000 ; 275 : 31505–31513. [CrossRef] [PubMed] [Google Scholar]
  29. Shibata M, Lu T, Furuya T, et al. Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1. J Biol Chem 2006 ; 281 : 14474–14485. [CrossRef] [PubMed] [Google Scholar]
  30. Kaushik S, Cuervo AM. Proteostasis and aging. Nat Med 2015 ; 21 : 1406–1415. [CrossRef] [PubMed] [Google Scholar]
  31. Colman RJ, Anderson RM, Johnson SC, et al. Caloric restriction delays disease onset and mortality in rhesus monkeys. Science 2009 ; 325 : 201–204. [CrossRef] [PubMed] [Google Scholar]
  32. Collier TJ, Kanaan NM, Kordower JH. Ageing as a primary risk factor for Parkinson’s disease: evidence from studies of non-human primates. Nat Rev Neurosci 2011 ; 12 : 359–366. [CrossRef] [Google Scholar]
  33. Bourdenx M, Dovero S, Engeln M, et al. Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by alpha-synuclein overexpression. Acta Neuropathol Commun 2015 ; 3 : 46. [CrossRef] [PubMed] [Google Scholar]
  34. Spencer B, Potkar R, Trejo M, et al. Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson’s and Lewy body diseases. J Neurosci 2009 ; 29 : 13578–13588. [CrossRef] [PubMed] [Google Scholar]
  35. Decressac M, Mattsson B, Weikop P, et al. TFEB-mediated autophagy rescues midbrain dopamine neurons from alpha-synuclein toxicity. Proc Natl Acad Sci USA 2013 ; 110 : E1817–E1826. [CrossRef] [Google Scholar]
  36. Bauer PO, Goswami A, Wong HK, et al. Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein. Nat Biotechnol 2010 ; 28 : 256–263. [CrossRef] [PubMed] [Google Scholar]
  37. Eskelinen EL. Doctor Jekyll and Mister Hyde: autophagy can promote both cell survival and cell death. Cell Death Differ 2005 ; 12 (suppl 2) : 1468–1472. [CrossRef] [Google Scholar]
  38. Niu XY, Huang HJ, Zhang JB, et al. Deletion of autophagy-related gene 7 in dopaminergic neurons prevents their loss induced by MPTP. Neuroscience 2016 ; 339 : 22–31. [CrossRef] [PubMed] [Google Scholar]
  39. Bourdenx M, Daniel J, Genin E, et al. Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases. Autophagy 2016 ; 12 : 472–483. [CrossRef] [PubMed] [Google Scholar]
  40. Lee JH, McBrayer MK, Wolfe DM, et al. Presenilin 1 maintains lysosomal Ca2+ homeostasis via TRPML1 by regulating vATPase-mediated lysosome acidification. Cell Rep 2015 ; 12 : 1430–1444. [CrossRef] [PubMed] [Google Scholar]
  41. Ha J, Kim J. Novel pharmacological modulators of autophagy: an updated patent review (2012–2015). Expert Opin Ther Pat 2016 ; 26 : 1273–1289. [CrossRef] [Google Scholar]
  42. Gual P, Gilgenkrantz H, Lotersztajn S. L’autophagie dans les maladies chroniques du foie : un ami qui vous veut (presque) toujours du bien !. Med Sci (Paris) 2017 ; 33 : 252–259. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  43. Galluzzi L. Bravo-San Pedro JM, Kroemer G. Autophagie, forme et longévité. Med Sci (Paris) 2017 ; 33 : 246–251. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.