Free Access
Med Sci (Paris)
Volume 30, Number 2, Février 2014
Page(s) 139 - 141
Section Nouvelles
Published online 24 February 2014
  1. Mouillet-Richard S, Ermonval M, Chebassier C, et al. Signal transduction through prion protein. Science 2000 ; 289 : 1925–1928. [CrossRef] [PubMed] [Google Scholar]
  2. Schneider B, Pietri M, Pradines E, et al. Understanding the neurospecificity of Prion protein signaling. Front Biosci 2011 ; 16 : 169–186. [CrossRef] [Google Scholar]
  3. Westergard L, Turnbaugh JA, Harris DA. A naturally occurring, C-terminal fragment of the prion protein delays disease and acts as a dominant negative inhibitor of PrPSc formation. J Biol Chem 2011 ; 286 : 44234–44242. [CrossRef] [PubMed] [Google Scholar]
  4. Vincent B, Paitel E, Saftig P, et al. The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein. J Biol Chem 2001 ; 276 : 37743–37746. [CrossRef] [PubMed] [Google Scholar]
  5. Yadavalli R, Guttmann RP, Seward T, et al. Calpain-dependent endoproteolytic cleavage of PrPSc modulates scrapie prion propagation. J Biol Chem 2004 ; 279 : 21948–21956. [CrossRef] [PubMed] [Google Scholar]
  6. Pietri M, Dakowski C, Hannaoui S, et al. PDK1 decreases TACE-mediated alpha-secretase activity and promotes disease progression in prion and Alzheimer’s diseases. Nat Med 2013 ; 19 : 1124–1131. [CrossRef] [PubMed] [Google Scholar]
  7. Allinson TM, Parkin ET, Turner AJ, Hooper NM. ADAMs family members as amyloid precursor protein alpha-secretases. J Neurosci Res 2003 ; 74 : 342–352. [CrossRef] [PubMed] [Google Scholar]
  8. De Strooper B. Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process. Physiol Rev 2010 ; 90 : 465–494. [CrossRef] [PubMed] [Google Scholar]
  9. Sennvik K, Fastbom J, Blomberg M, et al. Levels of alpha- and beta-secretase cleaved amyloid precursor protein in the cerebrospinal fluid of Alzheimer’s disease patients. Neurosci Lett 2000 ; 278 : 169–172. [CrossRef] [PubMed] [Google Scholar]
  10. Pietri M, Caprini A, Mouillet-Richard S, et al. Overstimulation of PrPC signaling pathways by prion peptide 106–126 causes oxidative injury of bioaminergic neuronal cells. J Biol Chem 2006 ; 281 : 28470–28479. [CrossRef] [PubMed] [Google Scholar]
  11. Pradines E, Hernandez-Rapp J, Villa-Diaz A, et al. Pathogenic prions deviate PrP(C) signaling in neuronal cells, impair A-beta clearance. Cell Death Dis 2013 ; 4 : e456. [CrossRef] [PubMed] [Google Scholar]
  12. Lauren J, Gimbel DA, Nygaard HB, et al. Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers. Nature 2009 ; 457 : 1128–1132. [CrossRef] [PubMed] [Google Scholar]
  13. Benilova I, De Strooper B. Prion protein in Alzheimer’s pathogenesis: a hot and controversial issue. EMBO Mol Med 2010 ; 2 : 289–290. [CrossRef] [PubMed] [Google Scholar]
  14. Um JW, Nygaard HB, Heiss JK, et al. Alzheimer amyloid-beta oligomer bound to postsynaptic prion protein activates Fyn to impair neurons. Nat Neurosci 2012 ; 15 : 1227–1235. [CrossRef] [PubMed] [Google Scholar]
  15. Larson M, Sherman MA, Amar F, et al. The complex PrP(c)-Fyn couples human oligomeric Abeta with pathological tau changes in Alzheimer’s disease. J Neurosci 2012 ; 32 : 16857–1671a. [CrossRef] [PubMed] [Google Scholar]
  16. Gill ON, Spencer Y, Richard-Loendt A, et al. Prevalent abnormal prion protein in human appendixes after bovine spongiform encephalopathy epizootic: large scale survey. Br Med J 2013 ; 347 : f5675. [CrossRef] [PubMed] [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.