Free Access
Med Sci (Paris)
Volume 23, Number 10, Octobre 2007
Page(s) 826 - 833
Section M/S revues
Published online 15 October 2007
  1. Mann KG, Nesheim ME, Church WR, et al. Surface-dependent reactions of the vitamin K-dependent enzyme complexes. Blood 1990; 76 : 1–16. [Google Scholar]
  2. Wallin R, Hutson SM. Warfarin and the vitamin K-dependent gamma-carboxylation system. Trends Mol Med 2004; 10 : 299–302. [Google Scholar]
  3. Furie B, Bouchard BA, Furie BC. Vitamin K-dependent biosynthesis of gamma-carboxyglutamic acid. Blood 1999; 93 : 1798–808. [Google Scholar]
  4. Scully M. Warfarin therapy. The Biochemist 2002; 24 : 15–7. [Google Scholar]
  5. Preissner KT, Nawroth PP, Kanse SM. Vascular protease receptors : integrating haemostasis and endothelial cell functions. J Pathol 2000; 190 : 360–72. [Google Scholar]
  6. Carmeliet P. Biomedicine. Clotting factors build blood vessels. Science 2001; 293 : 1602–4. [Google Scholar]
  7. Leger AJ, Covic L, Kuliopulos A. Protease-activated receptors in cardiovascular diseases. Circulation 2006; 114 : 1070–7. [Google Scholar]
  8. Manfioletti G, Brancolini C, Avanzi G, Schneider C. The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade. Mol Cell Biol 1993; 13 : 4976–85. [Google Scholar]
  9. He X, Shen L, Bjartell A, Dahlback B. The gene encoding vitamin K-dependent anticoagulant protein S is expressed in multiple rabbit organs as demonstrated by northern blotting, in situ hybridization, and immunohistochemistry. J Histochem Cytochem 1995; 43 : 85–96. [Google Scholar]
  10. Prasad D, Rothlin CV, Burrola P, et al. TAM receptor function in the retinal pigment epithelium. Mol Cell Neurosci 2006; 33 : 96–108. [Google Scholar]
  11. Hafizi S, Dahlback B. Signalling and functional diversity within the Axl subfamily of receptor tyrosine kinases. Cytokine Growth Factor Rev 2006; 17 : 295–304. [Google Scholar]
  12. Lu Q, Lemke G. Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family. Science 2001; 293 : 306–11. [Google Scholar]
  13. Demarchi F, Verardo R, Varnum B, et al. Gas6 anti-apoptotic signaling requires NF-kappa B activation. J Biol Chem 2001; 276 : 31738–44. [Google Scholar]
  14. Sharif MN, Sosic D, Rothlin CV, et al. Twist mediates suppression of inflammation by type I IFNs and Axl. J Exp Med 2006; 203 : 1891–901. [Google Scholar]
  15. Scott RS, McMahon EJ, Pop SM, et al. Phagocytosis and clearance of apoptotic cells is mediated by MER. Nature 2001; 411 : 207–11. [Google Scholar]
  16. Lu Q, Gore M, Zhang Q, et al. Tyro-3 family receptors are essential regulators of mammalian spermatogenesis. Nature 1999; 398 : 723–8. [Google Scholar]
  17. Prieto AL, Weber JL, Lai C. Expression of the receptor protein-tyrosine kinases Tyro-3, Axl, and mer in the developing rat central nervous system. J Comp Neurol 2000; 425 : 295–314. [Google Scholar]
  18. Romero EE, Velazquez-Estades LJ, Deo R et al. Cloning of rat vitamin K-dependent gamma-glutamyl carboxylase and developmentally regulated gene expression in postimplantation embryos. Exp Cell Res 1998; 243 : 334–46. [Google Scholar]
  19. Hall MO, Obin MS, Heeb MJ, et al. Both protein S and Gas6 stimulate outer segment phagocytosis by cultured rat retinal pigment epithelial cells. Exp Eye Res 2005; 81 : 581–91. [Google Scholar]
  20. D’Cruz PM, Yasumura D, Weir J, et al. Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat. Hum Mol Genet 2000; 9 : 645–51. [Google Scholar]
  21. Duncan JL, LaVail MM, Yasumura D, et al. An RCS-like retinal dystrophy phenotype in mer knockout mice. Invest Ophthalmol Vis Sci 2003; 44 : 826–38. [Google Scholar]
  22. Katagiri M, Hakeda Y, Chikazu D, et al. Mechanism of stimulation of osteoclastic bone resorption through Gas6/Tyro 3, a receptor tyrosine kinase signaling, in mouse osteoclasts. J Biol Chem 2001; 276 : 7376–82. [Google Scholar]
  23. Pierre-Jacques H, Glueck CJ, Mont MA, et al. Familial heterozygous protein-S deficiency in a patient who had multifocal osteonecrosis. A case report. J Bone Joint Surg Am 1997; 79 : 1079–84. [Google Scholar]
  24. Angelillo-Scherrer A, Burnier L, Flores N, et al. Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy. J Clin Invest 2005; 115 : 237–46. [Google Scholar]
  25. Jiang J, Kini V, Belikova N, et al. Cytochrome c release is required for phosphatidylserine peroxidation during Fas-triggered apoptosis in lung epithelial A549 cells. Lipids 2004; 39 : 1133–42. [Google Scholar]
  26. Fadok VA, Bratton DL, Rose DM, et al. A receptor for phosphatidylserine-specific clearance of apoptotic cells. Nature 2000; 405 : 85–90. [Google Scholar]
  27. Cohen PL, Caricchio R, Abraham V, et al. Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase. J Exp Med 2002; 196 : 135–40. [Google Scholar]
  28. Nakano T, Ishimoto Y, Kishino J, et al. Cell adhesion to phosphatidylserine mediated by a product of growth arrest-specific gene 6. J Biol Chem 1997; 272 : 29411–4. [Google Scholar]
  29. Neubauer A, Fiebeler A, Graham DK, et al. Expression of axl, a transforming receptor tyrosine kinase, in normal and malignant hematopoiesis. Blood 1994; 84 : 1931–41. [Google Scholar]
  30. Anderson HA, Maylock CA, Williams JA, et al. Serum-derived protein S binds to phosphatidylserine and stimulates the phagocytosis of apoptotic cells. Nat Immunol 2003; 4 : 87–91. [Google Scholar]
  31. Wu Y, Tibrewal N, Birge RB. Phosphatidylserine recognition by phagocytes : a view to a kill. Trends Cell Biol 2006; 16 : 189–97. [Google Scholar]
  32. Brugnera E, Haney L, Grimsley C, et al. Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex. Nat Cell Biol 2002; 4 : 574–82. [Google Scholar]
  33. Todt JC, Hu B, Curtis JL. The receptor tyrosine kinase MerTK activates phospholipase C gamma2 during recognition of apoptotic thymocytes by murine macrophages. J Leukoc Biol 2004; 75 : 705–13. [Google Scholar]
  34. Stitt TN, Conn G, Gore M, et al. The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases. Cell 1995; 80 : 661–70. [Google Scholar]
  35. McKay D, Marron C, Brown R. Testicular infarction secondary to protein S deficiency : a case report. BMC Urol 2006; 6 : 17. [Google Scholar]
  36. Feistritzer C, Lenta R, Riewald M. Protease-activated receptors-1 and -2 can mediate endothelial barrier protection : role in factor Xa signaling. J Thromb Haemost 2005; 3 : 2798–805. [Google Scholar]
  37. Yang X, Walsh PN. An ordered sequential mechanism for factor IX and factor IXa binding to platelet receptors in the assembly of the factor X-activating complex. Biochem J 2005; 390 : 157–67. [Google Scholar]
  38. Guo H, Liu D, Gelbard H, et al. Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3. Neuron 2004; 41 : 563–72. [Google Scholar]
  39. Domotor E, Benzakour O, Griffin JH, et al. Activated protein C alters cytosolic calcium flux in human brain endothelium via binding to endothelial protein C receptor and activation of protease activated receptor-1. Blood 2003; 101 : 4797–801. [Google Scholar]
  40. Broze GJ Jr. Protein Z-dependent regulation of coagulation. Thromb Haemost 2001; 86 : 8–13. [Google Scholar]
  41. Hafizi S, Dahlback B. Gas6 and protein S. Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily. FEBS J 2006; 273 : 5231–44. [Google Scholar]
  42. Maillard C, Berruyer M, Serre CM, et al. Protein-S, a vitamin K-dependent protein, is a bone matrix component synthesized and secreted by osteoblasts. Endocrinology 1992; 130 : 1599–604. [Google Scholar]
  43. Murshed M, Schinke T, McKee MD, Karsenty G. Extracellular matrix mineralization is regulated locally; different roles of two gla-containing proteins. J Cell Biol 2004; 165 : 625–30. [Google Scholar]
  44. Ducy P, Desbois C, Boyce B, et al. Increased bone formation in osteocalcin-deficient mice. Nature 1996; 382 : 448–52. [Google Scholar]
  45. Kulman JD, Harris JE, Xie L, Davie EW. Identification of two novel transmembrane gamma-carboxyglutamic acid proteins expressed broadly in fetal and adult tissues. Proc Natl Acad Sci USA 2001; 98 : 1370–5. [Google Scholar]
  46. Kulman JD, Harris JE, Haldeman BA, Davie EW. Primary structure and tissue distribution of two novel proline-rich gamma-carboxyglutamic acid proteins. Proc Natl Acad Sci USA 1997; 94 : 9058–62. [Google Scholar]
  47. Yanagita M, Ishimoto Y, Arai H, et al. Essential role of Gas6 for glomerular injury in nephrotoxic nephritis. J Clin Invest 2002; 110 : 239–46. [Google Scholar]
  48. Angelillo-Scherrer A, de Frutos P, Aparicio C, et al. Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis. Nat Med 2001; 7 : 215–21. [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.