Free Access
Med Sci (Paris)
Volume 20, Number 10, Octobre 2004
Page(s) 856 - 859
Section Nouvelles
Published online 15 October 2004
  1. Brunet A, Bonni A, Zigmond MJ, et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 1999; 96 : 857–68. [Google Scholar]
  2. Tran H, Brunet A, Griffith EC, Greenberg ME. The many forks in FOXO’s road. Science STKE 2003; RE5. [Google Scholar]
  3. Lin K, Dorman JB, Rodan A, Kenyon C. Daf-16 : an HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 1997; 278 : 1319–22. [Google Scholar]
  4. Giannakou ME, Goss M, Junger MA, et al. Long-lived Drosophila with overexpressed dFOXO in adult fat body. Science 2004; 305 : 361. [Google Scholar]
  5. Hwangbo DS, Gersham B, Tu MP, et al. Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body. Nature 2004; 429 : 562–6. [Google Scholar]
  6. Holzenberger M, Dupont J, Ducos B, et al. IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 2003; 421 : 182–7. [Google Scholar]
  7. Bluher M, Kahn BB, Kahn CR. Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 2003; 299 : 572–4. [Google Scholar]
  8. Brunet A, Sweeney LB, Sturgill JF, et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004; 303 : 2011–5. [Google Scholar]
  9. Motta MC, Divecha N, Lemieux M, et al. Mammalian SIRT1 represses forkhead transcription factors. Cell 2004; 116 : 551–63. [Google Scholar]
  10. Van Der Horst A, Tertoolen LG, De Vries-Smits LM, et al. FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2SIRT1. J Biol Chem 2004; 279 : 28873–9. [Google Scholar]
  11. Guarente L. Sir2 links chromatin silencing, metabolism, and aging. Genes Dev 2000; 14 : 1021–6. [Google Scholar]
  12. Howitz KT, Bitterman KJ, Cohen HY, et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 2003; 425 : 191–6. [Google Scholar]
  13. Vaziri H, Dessain SK, Ng Eaton E, et al. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 2001; 107 : 149–59. [Google Scholar]
  14. Luo J, Nikolaev AY, Imai S, et al. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 2001; 107 : 137–48. [Google Scholar]
  15. Antebi A. Tipping the balance toward longevity. Dev Cell 2004; 6 : 315–6. [Google Scholar]
  16. Tissenbaum HA, Guarente L. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 2001; 410 : 227–30. [Google Scholar]
  17. Hu MC, Lee DF, Xia W, et al. IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell 2004; 117 : 225–37. [Google Scholar]
  18. Seoane J, Le HV, Shen L, et al. Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation. Cell 2004; 117 : 211–23. [Google Scholar]
  19. Sandri M, Sandri C, Gilbert A, et al. Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 2004; 117 : 399–412. [Google Scholar]
  20. Stitt TN, Drujan D, Clarke BA, et al. The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol Cell 2004; 14 : 395–403. [Google Scholar]
  21. Castrillon DH, Miao L, Kollipara R, et al. Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a. Science 2003; 301 : 215–8. [Google Scholar]
  22. Hosaka T, Biggs WH 3rd, Tieu D, et al. Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification. Proc Natl Acad Sci USA 2004; 101 : 2975–80. [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.