Open Access
Tableau IV.
Principaux vaccins non-réplicatifs contre la dengue.
| Type | Vaccin | Entreprise | Mécanisme | Phase de développement | Références |
|---|---|---|---|---|---|
| Inactivé | TPIV | GSK, Firocruz and WRAIR Merck | Mélange de quatre souches de DENV-1 à 4 inactivées au formaldéhyde et purifiées | Phase I | [83,84] |
| Sous-unités recombinantes | V180 | GSK, Firocruz and WRAIR Merck | Utilisation de DEN-80E, version de E tronquée de sa région C-terminale | Phase I/II | [85,86] |
| ADN | D1ME100 | US Naval Medical Research Center | Plasmide contenant les séquences codantes des protéines prM et E du DENV-1 | Phase I | [54] |
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