Open Access
Tableau II.
Principales molécules dirigées contre le DENV et visant des facteurs cellulaires.
| Cibles | HSP90 | DC-SIGN | Intégrine | Héparane sulfate | |||||
|---|---|---|---|---|---|---|---|---|---|
| Type cellulaire | Ubiquitaire | Cellules dendritiques | Cellules endothéliales Plaquettes | Cellules adhérentes | |||||
| Molécule | Lactoferrine bovine | Lactoferrine bovine | HHA | UDA | GNA | Peptide P4 de la protéine E | Lactoferrine bovine | Galactomannane sulfaté | PD1-CD44 |
| Mécanisme d’action | Inhibition de la fixation du DENV | ||||||||
| Référence | [63] | [64] | [65] | [63] | [66] | [67] | |||
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