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Tableau II.
Procédés d’ingénierie cellulaire permettant de distinguer les PTC et les MTI.
Préparations de thérapie cellulaireManipulations non substantielles* |
---|
Découpage |
Broyage |
Façonnage |
Centrifugation |
Trempage dans des solutions antibiotiques ou antimicrobiennes |
Stérilisation |
Irradiation |
Séparation, concentration ou purification de cellules |
Filtration |
Lyophilisation |
Congélation |
Cryoconservation |
Vitrification |
Médicaments de thérapie innovanteManipulations substantielles** |
Culture ex vivo |
Expansion/activation ex vivo |
Manipulation génétique (transfert de gènes, modification du génome) |
Altération du phénotype |
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