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Tableau II.
Procédés d’ingénierie cellulaire permettant de distinguer les PTC et les MTI.
| Préparations de thérapie cellulaireManipulations non substantielles* |
|---|
| Découpage |
| Broyage |
| Façonnage |
| Centrifugation |
| Trempage dans des solutions antibiotiques ou antimicrobiennes |
| Stérilisation |
| Irradiation |
| Séparation, concentration ou purification de cellules |
| Filtration |
| Lyophilisation |
| Congélation |
| Cryoconservation |
| Vitrification |
| Médicaments de thérapie innovanteManipulations substantielles** |
| Culture ex vivo |
| Expansion/activation ex vivo |
| Manipulation génétique (transfert de gènes, modification du génome) |
| Altération du phénotype |
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