Figure 1.
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Interactions entre cellules tumorales et cellules mésenchymateuses du stroma. Ces interactions et les voies de signalisation décrites favorisent la survie des cellules tumorales et la résistance aux thérapies anticancéreuses. EP : prostaglandin E2 receptor. BIM : membre de la famille Bcl2 proapoptotique ; FLIP : FLICE-like inhibitory protein (antiapoptotique) ; VEGF : vascular endothelial growth factor ; FGF : fibroblast growth factor ; PGE2 : prostaglandine E2.
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