EDP Sciences logo
Authentification abonné
Rechercher
Menu
Accueil Tous les numéros Volume 32 / Numéro 11 (Novembre 2016) Med Sci (Paris), 32 11 (2016) 952-960 Références
Accès gratuit
Numéro
Med Sci (Paris)
Volume 32, Numéro 11, Novembre 2016
Le microbiote : cet inconnu qui réside en nous
Page(s) 952 - 960
Section Le microbiote : cet inconnu qui réside en nous
DOI https://doi.org/10.1051/medsci/20163211010
Publié en ligne 23 décembre 2016
  1. Li J, Jia H, Cai X, et al. An integrated catalog of reference genes in the human gut microbiome. Nature Biotechnol 2014 ; 32 : 834–841. [Google Scholar]
  2. Sender R, Fuchs S, Milo R. Are we really vastly outnumbered? Revisiting the ratio of bacterial to host cells in humans. Cell 2016 ; 164 : 337–340. [CrossRef] [PubMed] [Google Scholar]
  3. Qin J, Li Y, Cai Z, et al. A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature 2012 ; 490 : 55–60. [CrossRef] [PubMed] [Google Scholar]
  4. Le Chatelier E, Nielsen T, Qin J, et al. Richness of human gut microbiome correlates with metabolic markers. Nature 2013 ; 500 : 541–546. [CrossRef] [PubMed] [Google Scholar]
  5. Bergstrom A, Skov TH, Bahl MI, et al. Establishment of intestinal microbiota during early life: a longitudinal, explorative study of a large cohort of Danish infants. Appl Environ Microbiol 2014 ; 80 : 2889–2900. [CrossRef] [PubMed] [Google Scholar]
  6. Qin J, Li R, Raes J, et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 2010 ; 464 : 59–65. [CrossRef] [PubMed] [Google Scholar]
  7. Emoto T, Yamashita T, Sasaki N, et al. Analysis of gut microbiota in coronary artery disease patients: a possible link between gut microbiota and coronary artery disease. J Atheroscler Thromb 2016 ; 23 : 908–921. [CrossRef] [PubMed] [Google Scholar]
  8. Cotillard A, Kennedy SP, Kong LC, et al. Dietary intervention impact on gut microbial gene richness. Nature 2013 ; 500 : 585–588. [CrossRef] [PubMed] [Google Scholar]
  9. Duboc H, Rajca S, Rainteau D, et al. Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases. Gut 2013 ; 62 : 531–539. [CrossRef] [PubMed] [Google Scholar]
  10. Rajca S, Grondin V, Louis E, et al. Alterations in the intestinal microbiome (dysbiosis) as a predictor of relapse after infliximab withdrawal in Crohn’s disease. Inflamm Bowel Dis 2014 ; 20 : 978–986. [PubMed] [Google Scholar]
  11. Lamas B, Richard ML, Leducq V, et al. CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands. Nat Med 2016 ; 22 : 598–605. [CrossRef] [PubMed] [Google Scholar]
  12. Albenberg L, Esipova TV, Judge CP, et al. Correlation between intraluminal oxygen gradient and radial partitioning of intestinal microbiota. Gastroenterology 2014 ; 147 : 1055–1063e8. [CrossRef] [PubMed] [Google Scholar]
  13. Kim F, Pham M, Luttrell I, et al. Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity. Circ Res 2007 ; 100 : 1589–1596. [CrossRef] [PubMed] [Google Scholar]
  14. Song MJ, Kim KH, Yoon JM, Kim JB. Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes. Biochem Biophys Res Commun 2006 ; 346 : 739–745. [CrossRef] [PubMed] [Google Scholar]
  15. Shi H, Kokoeva MV, Inouye K, et al. TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 2006 ; 116 : 3015–3025. [CrossRef] [PubMed] [Google Scholar]
  16. Amar J, Chabo C, Waget A, et al. Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment. EMBO Mol Med 2011 ; 3 : 559–572. [CrossRef] [PubMed] [Google Scholar]
  17. Hansson GC, Johansson ME. The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. Gut Microbes 2010 ; 1 : 51–54. [CrossRef] [PubMed] [Google Scholar]
  18. Atuma C, Strugala V, Allen A, Holm L. The adherent gastrointestinal mucus gel layer: thickness and physical state in vivo. Am J Physiol Gastrointest Liver Physiol 2001 ; 280 : G922–G929. [PubMed] [Google Scholar]
  19. Swidsinski A, Loening-Baucke V, Theissig F, et al. Comparative study of the intestinal mucus barrier in normal and inflamed colon. Gut 2007 ; 56 : 343–350. [CrossRef] [PubMed] [Google Scholar]
  20. Carneiro LA, Magalhaes JG, Tattoli I, et al. Nod-like proteins in inflammation and disease. J Pathol 2008 ; 214 : 136–148. [CrossRef] [PubMed] [Google Scholar]
  21. Kufer TA, Sansonetti PJ. Sensing of bacteria: NOD a lonely job. Curr Opin Microbiol 2007 ; 10 : 62–69. [CrossRef] [PubMed] [Google Scholar]
  22. Koren O, Spor A, Felin J, et al. Human oral, gut, and plaque microbiota in patients with atherosclerosis. Proc Natl Acad Sci USA 2011 ; 108 (suppl 1) : 4592–4598. [CrossRef] [Google Scholar]
  23. D’Aiuto F, Sabbah W, Netuveli G, et al. Association of the metabolic syndrome with severe periodontitis in a large U.S. population-based survey. J Clin Endocrinol Metab 2008 ; 93 : 3989–3994. [CrossRef] [PubMed] [Google Scholar]
  24. Preshaw PM, Alba AL, Herrera D, et al. Periodontitis and diabetes: a two-way relationship. Diabetologia 2012 ; 55 : 21–31. [CrossRef] [PubMed] [Google Scholar]
  25. Blasco-Baque V, Serino M, Vergnes JN, et al. High-fat diet induces periodontitis in mice through lipopolysaccharides (LPS) receptor signaling: protective action of estrogens. PLoS One 2012 ; 7 : e48220. [CrossRef] [PubMed] [Google Scholar]
  26. Preshaw PM, Lauffart B, Zak E, et al. Progression and treatment of chronic adult periodontitis. J Periodontol 1999 ; 70 : 1209–1220. [CrossRef] [PubMed] [Google Scholar]
  27. Borrell LN, Papapanou PN. Analytical epidemiology of periodontitis. J Clin Periodontol 2005 ; 32 (suppl 6) : 132–158. [CrossRef] [PubMed] [Google Scholar]
  28. Lakhssassi N, Elhajoui N, Lodter JP, et al. Antimicrobial susceptibility variation of 50 anaerobic periopathogens in aggressive periodontitis: an interindividual variability study. Oral Microbiol Immunol 2005 ; 20 : 244–252. [CrossRef] [PubMed] [Google Scholar]
  29. Holm NR, Belstrom D, Ostergaard JA, et al. Identification of individuals with undiagnosed diabetes and pre-diabetes in a Danish cohort attending dental treatment. J Periodontol 2016 ; 87 : 395–402. [CrossRef] [PubMed] [Google Scholar]
  30. Field CA, Gidley MD, Preshaw PM, Jakubovics N. Investigation and quantification of key periodontal pathogens in patients with type 2 diabetes. J Periodontal Res 2012 ; 47 : 470–478. [CrossRef] [PubMed] [Google Scholar]
  31. Demmer RT, Jacobs DR, Jr, Singh R, et al. Periodontal bacteria and prediabetes prevalence in ORIGINS: the oral infections, glucose intolerance, and insulin resistance study. J Dent Res 2015 ; 94 : S201–S211. [CrossRef] [Google Scholar]
  32. Zhang H, DiBaise JK, Zuccolo A, et al. Human gut microbiota in obesity and after gastric bypass. Proc Natl Acad Sci USA 2009 ; 106 : 2365–2370. [Google Scholar]
  33. Tremaroli V, Karlsson F, Werling M, et al. Roux-en-Y gastric bypass and Vertical banded gastroplasty induce long-term changes on the human gut microbiome contributing to fat mass regulation. Cell Metab 2015 ; 22 : 228–238. [Google Scholar]
  34. Bueter M, Abegg K, Seyfried F, et al. Roux-en-Y gastric bypass operation in rats. J Vis Exp 2012 ; 64 : e3940. [Google Scholar]
  35. Troy S, Soty M, Ribeiro L, et al. Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice. Cell Metab 2008 ; 8 : 201–211. [CrossRef] [MathSciNet] [PubMed] [Google Scholar]
  36. Parker HE, Wallis K, le Roux CW, et al. Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion. Br J Pharmacol 2012 ; 165 : 414–423. [CrossRef] [PubMed] [Google Scholar]
  37. Cani PD, Everard A, Duparc T. Gut microbiota, enteroendocrine functions and metabolism. Curr Opin Pharmacol 2013 ; 13 : 935–940. [CrossRef] [PubMed] [Google Scholar]
  38. Davis LM, Martinez I, Walter J, et al. Barcoded pyrosequencing reveals that consumption of galactooligosaccharides results in a highly specific bifidogenic response in humans. PLoS One 2011 ; 6 : e25200. [CrossRef] [PubMed] [Google Scholar]
  39. Baer DJ, Stote KS, Henderson T, et al. The metabolizable energy of dietary resistant maltodextrin is variable and alters fecal microbiota composition in adult men. J Nutr 2014 ; 144 : 1023–1029. [CrossRef] [PubMed] [Google Scholar]
  40. Delzenne NM, Neyrinck AM, Cani PD. Gut microbiota and metabolic disorders: How prebiotic can work?. Br J Nutr 2013 ; 109 (suppl 2) : S81–S85. [CrossRef] [PubMed] [Google Scholar]
  41. Forslund K, Hildebrand F, Nielsen T, et al. Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. Nature 2015 ; 528 : 262–266. [CrossRef] [PubMed] [Google Scholar]
  42. Cabreiro F, Au C, Leung KY, et al. Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism. Cell 2013 ; 153 : 228–239. [CrossRef] [PubMed] [Google Scholar]
  43. Yassour M, Lim MY, Yun HS, et al. Sub-clinical detection of gut microbial biomarkers of obesity and type 2 diabetes. Genome Med 2016 ; 8 : 17. [CrossRef] [PubMed] [Google Scholar]
  44. Vrieze A, Van Nood E, Holleman F, et al. Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome. Gastroenterology 2012 ; 143 : 913–916e7. [CrossRef] [PubMed] [Google Scholar]
  45. Cani PD, Amar J, Iglesias MA, et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 2007 ; 56 : 1761–1772. [CrossRef] [PubMed] [Google Scholar]
  46. Cani PD, Bibiloni R, Knauf C, et al. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 2008 ; 57 : 1470–1481. [CrossRef] [PubMed] [Google Scholar]
  47. Verges B, Duvillard L, Lagrost L, et al. Changes in lipoprotein kinetics associated with type 2 diabetes affect the distribution of lipopolysaccharides among lipoproteins. J Clin Endocrinol Metab 2014 ; 99 : E1245–E1253. [CrossRef] [PubMed] [Google Scholar]
  48. Schertzer JD, Tamrakar AK, Magalhaes JG, et al. NOD1 activators link innate immunity to insulin resistance. Diabetes 2011 ; 60 : 2206–2215. [CrossRef] [PubMed] [Google Scholar]
  49. Cani PD, Possemiers S, Van de Wiele T, et al. Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability. Gut 2009 ; 58 : 1091–1103. [CrossRef] [PubMed] [Google Scholar]
  50. Hirose S, Ono HK, Omoe K, et al. Goblet cells are involved in translocation of staphylococcal enterotoxin A in the intestinal tissue of house musk shrew (Suncus murinus). J Appl Microbiol 2016 ; 120 : 781–789. [CrossRef] [PubMed] [Google Scholar]
  51. Koh IH, Liberatore AM, Menchaca-Diaz JL, et al. Bacterial translocation, microcirculation injury and sepsis. Endocr Metab Immune Dis Drug Targets 2006 ; 6 : 143–150. [Google Scholar]
  52. Sandek A, Bauditz J, Swidsinski A, et al. Altered intestinal function in patients with chronic heart failure. J Am Coll Cardiol 2007 ; 50 : 1561–1569. [CrossRef] [PubMed] [Google Scholar]
  53. Gutierrez A, Holler E, Zapater P, et al. Antimicrobial peptide response to blood translocation of bacterial DNA in Crohn’s disease is affected by NOD2/CARD15 genotype. Inflamm Bowel Dis 2011 ; 17 : 1641–1650. [CrossRef] [PubMed] [Google Scholar]
  54. Everard A, Belzer C, Geurts L, et al. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc Natl Acad Sci USA 2013 ; 110 : 9066–9071. [CrossRef] [Google Scholar]
  55. Berg RD. Bacterial translocation from the gastrointestinal tract. Trends Microbiol 1995 ; 3 : 149–154. [CrossRef] [PubMed] [Google Scholar]
  56. Amar J, Burcelin R, Ruidavets JB, et al. Energy intake is associated with endotoxemia in apparently healthy men. Am J Clin Nutr 2008 ; 87 : 1219–1223. [CrossRef] [PubMed] [Google Scholar]
  57. Burcelin R, Serino M, Chabo C, et al. Metagenome and metabolism: the tissue microbiota hypothesis. Diabetes Obes Metab 2013 ; 15 (suppl 3) : 61–70. [CrossRef] [PubMed] [Google Scholar]
  58. Amar J, Lange C, Payros G, et al. Blood microbiota dysbiosis is associated with the onset of cardiovascular events in a large general population: the D.E.S.I.R. study. PLoS One 2013 ; 8 : e54461. [CrossRef] [PubMed] [Google Scholar]
  59. Amar J, Serino M, Lange C, et al. Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept. Diabetologia 2011 ; 54 : 3055–3061. [CrossRef] [PubMed] [Google Scholar]
  60. Luche E, Cousin B, Garidou L, et al. Metabolic endotoxemia directly increases the proliferation of adipocyte precursors at the onset of metabolic diseases through a CD14-dependent mechanism. Mol Metab 2013 ; 2 : 281–291. [CrossRef] [PubMed] [Google Scholar]
  61. Garidou L, Pomie C, Klopp P, et al. The gut microbiota regulates intestinal CD4 T cells expressing RORgammat and controls metabolic disease. Cell Metab 2015 ; 22 : 100–112. [CrossRef] [PubMed] [Google Scholar]
  62. Blasco-Baque V, Garidou L, Pomié C, et al. E. Periodontitis induced by Porphyromonas gingivalis drives periodontal microbiota dysbiosis and insulin-resistance via an impaired adaptive immune response. Gut 2016 ; doi : 10.1136/gutjnl-2015-309897. [Google Scholar]
  63. Ishikawa M, Yoshida K, Okamura H, et al. Oral Porphyromonas gingivalis translocates to the liver and regulates hepatic glycogen synthesis through the Akt/GSK-3beta signaling pathway. Biochim Biophys Acta 2013 ; 1832 : 2035–2043. [CrossRef] [PubMed] [Google Scholar]
  64. Reichert S, Altermann W, Stein JM, et al. Individual composition of human leukocyte antigens and periodontopathogens in the background of periodontitis. J Periodontol 2013 ; 84 : 100–109. [CrossRef] [PubMed] [Google Scholar]
  65. Genser L, Poitou C, Brot-Laroche E, et al. L’altération de la perméabilité intestinale : chaînon manquant entre dysbiose et inflammation au cours de l’obésité ?. Med Sci (Paris) 2016 ; 32 : 461–469. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  66. Blottière HM, Doré J. Impact des nouveaux outils de métagénomique sur notre connaissance du microbiote intestinal et de son rôle en santé humaine : enjeux diagnostiques et thérapeutiques. Med Sci (Paris) 2016 ; 32 : 944–951. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  67. Thorens B. Incrétines, sécrétion d’insuline et diabète. Med Sci (Paris) 2003 ; 19 : 860–863. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  68. Lagier JC, Raoult D. Greffe de microbiote fécal et infections : mise au point, perspectives. Med Sci (Paris) 2016 ; 32 : 991–997. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  69. Weissenbach J, Sghir A. Microbiotes et métagénomique. Med Sci (Paris) 2016 ; 32 : 937–943. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]

Les statistiques affichées correspondent au cumul d'une part des vues des résumés de l'article et d'autre part des vues et téléchargements de l'article plein-texte (PDF, Full-HTML, ePub... selon les formats disponibles) sur la platefome Vision4Press.

Les statistiques sont disponibles avec un délai de 48 à 96 heures et sont mises à jour quotidiennement en semaine.

Le chargement des statistiques peut être long.