Accès gratuit
Numéro
Med Sci (Paris)
Volume 32, Numéro 3, Mars 2016
Page(s) 281 - 289
Section M/S Revues
DOI https://doi.org/10.1051/medsci/20163203013
Publié en ligne 23 mars 2016
  1. Codogno P. Les gènes ATG et la macro-autophagie. Med Sci (Paris) 2004 ; 20 : 734–736. [CrossRef] [EDP Sciences] [PubMed]
  2. Feng Y, He D, Yao Z, Klionsky DJ The machinery of macroautophagy. Cell Res 2014 ; 24 : 24–41. [CrossRef] [PubMed]
  3. Subramani S, Malhotra V Non-autophagic roles of autophagy-related proteins. EMBO Rep 2013 ; 14 : 143–151. [CrossRef] [PubMed]
  4. Deretic V, Saitoh T, Akira S Autophagy in infection, inflammation and immunity. Nat Rev Immunol 2013 ; 13 : 722–737. [CrossRef] [PubMed]
  5. Joubert PE, Grégoire IP, Meiffren G, et al. Autophagie et pathogènes. Med Sci (Paris) 2011 ; 27 : 41–47. [CrossRef] [EDP Sciences] [PubMed]
  6. Gomes LC, Dikic I Autophagy in antimicrobial immunity. Mol Cell 2014 ; 54 : 224–233. [CrossRef] [PubMed]
  7. Glasser AL, Lapaquette P, Darfeuille-Michaud A Altération de l’autophagie chez les patients atteints de maladie de Crohn. Med Sci (Paris) 2009 ; 25 : 349–351. [CrossRef] [EDP Sciences] [PubMed]
  8. Gardet A, Xavier RJ Common alleles that influence autophagy and the risk for inflammatory bowel disease. Curr Opin Immunol 2012 ; 24 : 522–529. [CrossRef] [PubMed]
  9. Mintern JD, Macri C, Villadangos JA Modulation of antigen presentation by intracellular trafficking. Curr Opin Immunol 2015 ; 34 : 16–21. [CrossRef] [PubMed]
  10. Pua HH, Dzhagalov I, Chuck M, et al. A critical role for the autophagy gene Atg5 in T cell survival and proliferation. J Exp Med 2007 ; 204 : 25–31. [CrossRef] [PubMed]
  11. Pua HH, Guo J, Komatsu M, He YW Autophagy is essential for mitochondrial clearance in mature T lymphocytes. J Immunol 2009 ; 182 : 4046–4055. [CrossRef]
  12. Stephenson LM, Miller BC, Ng A, et al. Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes. Autophagy 2009 ; 5 : 625–635. [CrossRef] [PubMed]
  13. Salio M, Puleston DJ, Mathan TSM, et al. Essential role for autophagy during invariant NKT cell development. Proc Natl Acad Sci USA 2014 ; 111 : E5678–E5687. [CrossRef]
  14. Miller BC, Zhao Z, Stephenson LM, et al. The autophagy gene ATG5 plays an essential role in B lymphocyte development. Autophagy 2008 ; 4 : 309–314. [CrossRef] [PubMed]
  15. Hamze M, Desmetz C, Guglielmi P. Les lymphocytes B. Med Sci (Paris) 2014 ; 30 : 874–881. [CrossRef] [EDP Sciences]
  16. Mortensen M, Soilleux EJ, Djordjevic G, et al. The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance. J Exp Med 2011 ; 208 : 455–467. [CrossRef] [PubMed]
  17. Nedjic J, Aichinger M, Emmerich J, et al. Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance. Nature 2008 ; 455 : 396–400. [CrossRef] [PubMed]
  18. Sukseree S, Mildner M, Rossiter H, et al. Autophagy in the thymic epithelium is dispensable for the development of self-tolerance in a novel mouse model. PLoS One 2012 ; 7 : e38933. [CrossRef] [PubMed]
  19. Lopes N, Ferrier P, Irla M Induction de la tolérance centrale dans le thymus par le facteur de transcription Aire. Med Sci (Paris) 2015 ; 31 : 742–747. [CrossRef] [EDP Sciences] [PubMed]
  20. Aichinger M, Wu C, Nedjic J, Klein L Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance. J Exp Med 2013 ; 210 : 287–300. [CrossRef] [PubMed]
  21. Schuster C, Gerold KD, Schober K, et al. The autoimmunity-associated gene CLEC16A modulates thymic epithelial cell autophagy and alters T cell selection. Immunity 2015 ; 42 : 942–952. [CrossRef] [PubMed]
  22. Jia W, He YW Temporal regulation of intracellular organelle homeostasis in T lymphocytes by autophagy. J Immunol 2011 ; 186 : 5313–5322. [CrossRef]
  23. Jia W, Pua HH, Li QJ, He YW Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes. J Immunol 2011 ; 186 : 1564–1574. [CrossRef]
  24. Hubbard VM, Valdor R, Patel B, et al. Macroautophagy regulates energy metabolism during effector T cell activation. J Immunol 2010 ; 185 : 7349–7357. [CrossRef]
  25. Kovacs JR, Li C, Yang Q, et al. Autophagy promotes T-cell survival through degradation of proteins of the cell death machinery. Cell Death Differ 2012 ; 19 : 144–152. [CrossRef] [PubMed]
  26. Li C, Capan E, Zhao Y, et al. Autophagy is induced in CD4+ T cells and important for the growth factor-withdrawal cell death. J Immunol 2006 ; 177 : 5163–5168. [CrossRef]
  27. Watanabe K, Tsubata T Autophagy connects antigen receptor signaling to costimulatory signaling in B lymphocytes. Autophagy 2009 ; 5 : 108–110. [CrossRef] [PubMed]
  28. Clarke AJ, Ellinghaus U, Cortini A, et al. Autophagy is activated in systemic lupus erythematosus and required for plasmablast development. Ann Rheum Dis 2015 ; 74 : 912–920. [CrossRef] [PubMed]
  29. Ireland JM, Unanue ER Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells. J Exp Med 2011 ; 208 : 2625–2632. [CrossRef] [PubMed]
  30. Chen M, Hong MJ, Sun H, et al. Essential role for autophagy in the maintenance of immunological memory against influenza infection. Nat Med 2014 ; 20 : 503–510. [CrossRef] [PubMed]
  31. Pengo N, Scolari M, Oliva L, et al. Plasma cells require autophagy for sustainable immunoglobulin production. Nat Immunol 2013 ; 14 : 298–305. [CrossRef] [PubMed]
  32. Dengjel J, Schoor O, Fischer R, et al. Autophagy promotes MHC class II presentation of peptides from intracellular source proteins. Proc Natl Acad Sci USA 2005 ; 102 : 7922–7927. [CrossRef]
  33. Paludan C, Schmid D, Landthaler M, et al. Endogenous MHC class II processing of a viral nuclear antigen after autophagy. Science 2005 ; 307 : 593–596. [CrossRef] [PubMed]
  34. Chaturvedi A, Dorward D, Pierce SK The B cell receptor governs the subcellular location of toll-like receptor 9 leading to hyperresponses to DNA-containing antigens. Immunity 2008 ; 28 : 799–809. [CrossRef] [PubMed]
  35. Münz C, Of LAP CUPS, and DRibbles: unconventional use of autophagy proteins for MHC restricted antigen presentation. Front Immunol 2015 ; 6 : 200.
  36. Puleston DJ, Zhang H, Powell TJ, et al. Autophagy is a critical regulator of memory CD8+ T cell formation. Elife 2014 ; 3.
  37. Xu X, Araki K, Li S, et al. Autophagy is essential for effector CD8+ T cell survival and memory formation. Nat immunol 2014 ; 15 : 1152–1161. [CrossRef] [PubMed]
  38. Schlie K, Westerback A, DeVorkin L, et al. Survival of effector CD8+ T cells during influenza infection is dependent on autophagy. J Immunol 2015 ; 194 : 4277–4286. [CrossRef]
  39. Conway KL, Kuballa P, Khor B, et al. ATG5 regulates plasma cell differentiation. Autophagy 2013 ; 9 : 528–537. [CrossRef] [PubMed]
  40. Chen M, Kodali S, Jang A, et al. Requirement for autophagy in the long-term persistence but not initial formation of memory B cells. J Immunol 2015 ; 194 : 2607–2615. [CrossRef]
  41. Alirezaei M, Fox HS, Flynn CT, et al. Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis. Autophagy 2009 ; 5 : 152–158. [CrossRef] [PubMed]
  42. Harley JB, Alarcon-Riquelme ME, Criswell LA, et al. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 2008 ; 40 : 204–210. [CrossRef] [PubMed]
  43. Zhou XJ, Lu XL, Lv JC, et al. Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese population. Ann Rheum Dis 2011 ; 70 : 1330–1337. [CrossRef] [PubMed]
  44. Martin LJ, Gupta J, Jyothula SS, et al. Functional variant in the autophagy-related 5 gene promotor is associated with childhood asthma. PLoS One 2012 ; 7 : e33454. [CrossRef] [PubMed]
  45. Page N, Gros F, Schall N, et al. HSC70 blockade by the therapeutic peptide P140 affects autophagic processes and endogenous MHCII presentation in murine lupus. Ann Rheum Dis 2011 ; 70 : 837–843. [CrossRef] [PubMed]
  46. Zimmer R, Scherbarth HR, Rillo OL, et al. Lupuzor/P140 peptide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled phase IIb clinical trial. Ann Rheum Dis 2013 ; 72 : 1830–1835. [CrossRef] [PubMed]
  47. Gros F, Arnold J, Page N, et al. Macroautophagy is deregulated in murine and human lupus T lymphocytes. Autophagy 2012 ; 8 : 1113–1123. [CrossRef] [PubMed]
  48. Alessandri C, Barbati C, Vacirca D, et al. T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy. FASEB J 2012 ; 26 : 4722–4732. [CrossRef] [PubMed]
  49. Caza TN, Fernandez DR, Talaber G, et al. HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE. Ann Rheum Dis 2014 ; 73 : 1888–1897. [CrossRef] [PubMed]
  50. Yang Z, Fujii H, Mohan SV, et al. Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells. J Exp Med 2013 ; 210 : 2119–2134. [CrossRef] [PubMed]
  51. Chen M, Kodali S, Jang A, et al. Requirement for autophagy in the long-term persistence but not initial formation of memory B cells. J Immunol 2015 ; 194 : 2607–2615. [CrossRef]

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