Accès gratuit
Numéro |
Med Sci (Paris)
Volume 31, Numéro 12, Décembre 2015
|
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Page(s) | 1083 - 1091 | |
Section | M/S Revues | |
DOI | https://doi.org/10.1051/medsci/20153112011 | |
Publié en ligne | 16 décembre 2015 |
- Rossouw JE, Prentice RL, Manson JE, et al. Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. JAMA 2007 ; 297 : 1465–1477. [CrossRef] [PubMed] [Google Scholar]
- Lenfant F, Tremollieres F, Gourdy P, Arnal JF. Timing of the vascular actions of estrogens in experimental and human studies: why protective early, and not when delayed? Maturitas 2011 ; 68 : 165–173. [CrossRef] [PubMed] [Google Scholar]
- McDonnell DP, Wardell SE. The molecular mechanisms underlying the pharmacological actions of ER modulators: implications for new drug discovery in breast cancer. Curr Opin Pharmacol 2010 ; 10 : 620–628. [CrossRef] [PubMed] [Google Scholar]
- Palmieri C, Patten DK, Januszewski A, et al. Breast cancer: current and future endocrine therapies. Mol Cell Endocrinol 2014 ; 382 : 695–723. [CrossRef] [PubMed] [Google Scholar]
- Jiang Q, Zheng S, Wang G. Development of new estrogen receptor-targeting therapeutic agents for tamoxifen-resistant breast cancer. Future Med Chem 2013 ; 5 : 1023–1035. [CrossRef] [PubMed] [Google Scholar]
- Heldring N, Pike A, Andersson S, et al. Estrogen receptors: how do they signal and what are their targets. Physiol Rev 2007 ; 87 : 905–931. [CrossRef] [PubMed] [Google Scholar]
- Lonard DM, O’Malley BW. Nuclear receptor coregulators: modulators of pathology and therapeutic targets. Nat Rev Endocrinol 2012 ; 8 : 598–604. [CrossRef] [PubMed] [Google Scholar]
- Kobayashi Y, Kitamoto T, Masuhiro Y, et al. p300 mediates functional synergism between AF-1 and AF-2 of estrogen receptor alpha and beta by interacting directly with the N-terminal A/B domains. J Biol Chem 2000 ; 275 : 15645–15651. [CrossRef] [PubMed] [Google Scholar]
- Metivier R, Penot G, Flouriot G, Pakdel F. Synergism between ERalpha transactivation function 1 (AF-1) and AF-2 mediated by steroid receptor coactivator protein-1: requirement for the AF-1 alpha-helical core and for a direct interaction between the N- and C-terminal domains. Mol Endocrinol 2001 ; 15 : 1953–1970. [PubMed] [Google Scholar]
- Onate SA, Boonyaratanakornkit V, Spencer TE, et al. The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors. J Biol Chem 1998 ; 273 : 12101–12108. [CrossRef] [PubMed] [Google Scholar]
- Benecke A, Chambon P, Gronemeyer H. Synergy between estrogen receptor α activation functions AF1 and AF2 mediated by transcription intermediary factor TIF2. EMBO Rep 2000 ; 1 : 151–157. [CrossRef] [PubMed] [Google Scholar]
- Tzukerman MT, Esty A, Santiso-Mere D, et al. Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions. Mol Endocrinol 1994 ; 8 : 21–30. [PubMed] [Google Scholar]
- Metivier R, Stark A, Flouriot G, et al. A dynamic structural model for estrogen receptor-alpha activation by ligands, emphasizing the role of interactions between distant A and E domains. Mol Cell 2002 ; 10 : 1019–1032. [CrossRef] [PubMed] [Google Scholar]
- Katzenellenbogen BS, Katzenellenbogen JA. Biomedicine. Defining the S in SERMs. Science 2002 ; 295 : 2380–2381. [Google Scholar]
- Billon-Gales A, Krust A, Fontaine C, et al. Activation function 2 (AF2) of estrogen receptor-[alpha] is required for the atheroprotective action of estradiol but not to accelerate endothelial healing. Proc Natl Acad Sci USA 2011 ; 108 : 13311–13316. [CrossRef] [Google Scholar]
- Billon-Gales A, Fontaine C, Filipe C, et al. The transactivating function 1 of estrogen receptor[alpha] is dispensable for the vasculoprotective actions of 17[beta]-estradiol. Proc Natl Acad Sci USA 2009 ; 106 : 2053–2058. [CrossRef] [Google Scholar]
- Adlanmerini M, Solinhac R, Abot A, et al. Mutation of the palmitoylation site of estrogen receptor alpha in vivo reveals tissue-specific roles for membrane versus nuclear actions. Proc Natl Acad Sci USA 2014 ; 111 : E283–E290. [CrossRef] [Google Scholar]
- Handgraaf S, Riant E, Fabre A, et al. Prevention of obesity and insulin resistance by estrogens requires ERalpha activation function-2 (ERalphaAF-2), whereas ERalphaAF-1 is dispensable. Diabetes 2013 ; 62 : 4098–4108. [CrossRef] [PubMed] [Google Scholar]
- Arao Y, Hamilton KJ, Ray MK, et al. Estrogen receptor alpha AF-2 mutation results in antagonist reversal and reveals tissue selective function of estrogen receptor modulators. Proc Natl Acad Sci USA 2011 ; 108 : 14986–14991. [CrossRef] [Google Scholar]
- Wu Q, Chambliss K, Umetani M, et al. Non-nuclear estrogen receptor signaling in the endothelium. J Biol Chem 2011 ; 286 : 14737–14743. [CrossRef] [PubMed] [Google Scholar]
- Brouchet L, Krust A, Dupont S, et al. Estradiol accelerates reendothelialization in mouse carotid artery through estrogen receptor-alpha but not estrogen receptor-beta. Circulation 2001 ; 103 : 423–428. [CrossRef] [PubMed] [Google Scholar]
- Darblade B, Pendaries C, Krust A, et al. Estradiol alters nitric oxide production in the mouse aorta through the alpha-, but not beta-, estrogen receptor. Circ Res 2002 ; 90 : 413–419. [CrossRef] [Google Scholar]
- Russell KS, Haynes MP, Sinha D, et al. Human vascular endothelial cells contain membrane binding sites for estradiol, which mediate rapid intracellular signaling. Proc Natl Acad Sci USA 2000 ; 97 : 5930–5935. [CrossRef] [Google Scholar]
- Kim KH, Toomre D, Bender JR. Splice isoform estrogen receptors as integral transmembrane proteins. Mol Biol Cell 2011 ; 22 : 4415–4423. [CrossRef] [PubMed] [Google Scholar]
- Kim KH, Bender JR. Membrane-initiated actions of estrogen on the endothelium. Mol Cell Endocrinol 2009 ; 308 : 3–8. [CrossRef] [PubMed] [Google Scholar]
- Chaudhri RA, Hadadi A, Lobachev KS, et al. Estrogen receptor-alpha 36 mediates the anti-apoptotic effect of estradiol in triple negative breast cancer cells via a membrane-associated mechanism. Biochim Biophys Acta 2014 ; 1843 : 2796–2806. [CrossRef] [PubMed] [Google Scholar]
- Acconcia F, Ascenzi P, Bocedi A, et al. Palmitoylation-dependent estrogen receptor alpha membrane localization: regulation by 17beta-estradiol. Mol Biol Cell 2005 ; 16 : 231–237. [CrossRef] [PubMed] [Google Scholar]
- Acconcia F, Ascenzi P, Fabozzi G, et al. S-palmitoylation modulates human estrogen receptor-alpha functions. Biochem Biophys Res Commun 2004 ; 316 : 878–883. [CrossRef] [PubMed] [Google Scholar]
- Migliaccio A, Castoria G, Di Domenico M, et al. Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation. EMBO J 2000 ; 19 : 5406–5417. [CrossRef] [PubMed] [Google Scholar]
- Li L, Hisamoto K, Kim KH, et al. Variant estrogen receptor-c-Src molecular interdependence and c-Src structural requirements for endothelial NO synthase activation. Proc Natl Acad Sci USA 2007 ; 104 : 16468–16473. [CrossRef] [Google Scholar]
- Le Romancer M, Treilleux I, Leconte N, et al. Regulation of estrogen rapid signaling through arginine methylation by PRMT1. Mol Cell 2008 ; 31 : 212–221. [CrossRef] [PubMed] [Google Scholar]
- Wu Q, Chambliss K, Lee WR, et al. Point mutations in the ERalpha Galphai binding domain segregate nonnuclear from nuclear receptor function. Mol Endocrinol 2013 ; 27 : 2–11. [CrossRef] [PubMed] [Google Scholar]
- Marino M, Ascenzi P. Membrane association of estrogen receptor alpha and beta influences 17beta-estradiol-mediated cancer cell proliferation. Steroids 2008 ; 73 : 853–858. [CrossRef] [PubMed] [Google Scholar]
- La Rosa P, Pesiri V, Leclercq G, et al. Palmitoylation regulates 17beta-estradiol-induced estrogen receptor-alpha degradation and transcriptional activity. Mol Endocrinol 2012 ; 26 : 762–774. [CrossRef] [PubMed] [Google Scholar]
- Chambliss KL, Simon L, Yuhanna IS, et al. Dissecting the basis of nongenomic activation of endothelial nitric oxide synthase by estradiol: role of ERalpha domains with known nuclear functions. Mol Endocrinol 2005 ; 19 : 277–289. [CrossRef] [PubMed] [Google Scholar]
- Razandi M, Pedram A, Merchenthaler I, et al. Plasma membrane estrogen receptors exist and functions as dimers. Mol Endocrinol 2004 ; 18 : 2854–2865. [CrossRef] [PubMed] [Google Scholar]
- Wendler A, Baldi E, Harvey BJ, et al. Position paper: rapid responses to steroids. Current status and future prospects. Eur J Endocrinol 2010 ; 162 : 825–830. [CrossRef] [PubMed] [Google Scholar]
- Lin AHY, Li RWS, Ho EYW, et al. Differential ligand binding affinities of human estrogen receptor-α isoforms. PLoS One 2013 ; 8 : e63199. [CrossRef] [PubMed] [Google Scholar]
- Harrington WR, Kim SH, Funk CC, et al. Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action. Mol Endocrinol 2006 ; 20 : 491–502. [CrossRef] [PubMed] [Google Scholar]
- Chambliss KL, Wu Q, Oltmann S, et al. Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice. J Clin Invest 2010 ; 120 : 2319–2330. [CrossRef] [PubMed] [Google Scholar]
- Li L, Haynes MP, Bender JR. Plasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cells. Proc Natl Acad Sci USA 2003 ; 100 : 4807–4812. [CrossRef] [Google Scholar]
- Pedram A, Razandi M, Lewis M, et al. Membrane-localized estrogen receptor a is required for normal organ development and function. Dev Cell 2014 ; 29 : 482–490. [CrossRef] [PubMed] [Google Scholar]
- Smith CL, O’Malley BW. Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev 2004 ; 25 : 45–71. [CrossRef] [PubMed] [Google Scholar]
- Fontaine C, Abot A, Billon-Gales A, et al. Tamoxifen elicits atheroprotection through estrogen receptor alpha AF-1 but does not accelerate reendothelialization. Am J Pathol 2013 ; 183 : 304–312. [CrossRef] [PubMed] [Google Scholar]
- Madak-Erdogan Z, Kieser KJ, Kim SH, et al. Nuclear and extranuclear pathway inputs in the regulation of global gene expression by estrogen receptors. Mol Endocrinol 2008 ; 22 : 2116–2127. [CrossRef] [PubMed] [Google Scholar]
- Visser M, Foidart JM. Coelingh Bennink HJ. In vitro effects of estetrol on receptor binding, drug targets and human liver cell metabolism. Climacteric 2008 ; 11 (suppl 1) : 64–68. [CrossRef] [PubMed] [Google Scholar]
- Abot A, Fontaine C, Buscato M, et al. The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor alpha modulation, uncoupling nuclear and membrane activation. EMBO Mol Med 2014 ; 10 : 1328–1346. [CrossRef] [PubMed] [Google Scholar]
- Canonico M, Plu-Bureau G, Lowe GD, Scarabin PY. Hormone replacement therapy and risk of venous thromboembolism in postmenopausal women: systematic review and meta-analysis. BMJ 2008 ; 336 : 1227–1231. [CrossRef] [PubMed] [Google Scholar]
- Brouchet L, Krust A, Dupont S, et al. Estradiol accelerates reendothelialization in mouse carotid artery through estrogen receptor-alpha but not estrogen receptor-beta. Circulation 2001 ; 103 : 423–428. [CrossRef] [PubMed] [Google Scholar]
- Mawet M, Maillard C, Klipping C, et al. Unique effects on hepatic function, lipid metabolism, bone and growth endocrine parameters of estetrol in combined oral contraceptives. Eur J Contracept Reprod Health Care 2015 ; 20 : 463–475. [PubMed] [Google Scholar]
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