Accès gratuit
Numéro
Med Sci (Paris)
Volume 31, Numéro 3, Mars 2015
Page(s) 275 - 281
Section M/S Revues
DOI https://doi.org/10.1051/medsci/20153103013
Publié en ligne 8 avril 2015
  1. O’Dowd BF, Heiber M, Chan A, et al. A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11. Gene 1993 ; 136 : 355–360. [CrossRef] [PubMed]
  2. Tatemoto K, Hosoya M, Habata Y, et al. Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem Biophys Res Commun 1998 ; 251 : 471–476. [CrossRef] [PubMed]
  3. Galanth C, Hus-Citharel A, Li B, Llorens-Cortes C. Apelin in the control of body fluid homeostasis and cardiovascular functions. Curr Pharm Des 2012 ; 18 : 789–798. [CrossRef] [PubMed]
  4. Llorens-Cortes C, Beaudet A. L’apéline, un inhibiteur naturel de l’effet antidiurétique de la vasopressine. Med Sci (Paris) 2005 ; 21 : 741–746. [CrossRef] [EDP Sciences] [PubMed]
  5. Masri B, Lahlou H, Mazarguil H, et al. Apelin (65–77) activates extracellular signal-regulated kinases via a PTX-sensitive G protein. Biochem Biophys Res Commun 2002 ; 290 : 539–545. [CrossRef] [PubMed]
  6. Masri B, Morin N, Pedebernade L, et al. The apelin receptor is coupled to Gi1 or Gi2 protein and is differentially desensitized by apelin fragments. J Biol Chem 2006 ; 281 : 18317–18326. [CrossRef] [PubMed]
  7. Szokodi I, Tavi P, Foldes G, et al. Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility. Circ Res 2002 ; 91 : 434–440. [CrossRef] [PubMed]
  8. Yue P, Jin H, Xu S, et al. Apelin decreases lipolysis via G(q), G(i), and AMPK-dependent mechanisms. Endocrinology 2011 ; 152 : 59–68. [CrossRef] [PubMed]
  9. O’Carroll AM, Lolait SJ, Harris LE, Pope GR. The apelin receptor APJ: journey from an orphan to a multifaceted regulator of homeostasis. J Endocrinol 2013 ; 219 : R13–R35. [CrossRef] [PubMed]
  10. Dray C, Knauf C, Daviaud D, et al. Apelin stimulates glucose utilization in normal and obese insulin-resistant mice. Cell Metab 2008 ; 8 : 437–445. [CrossRef] [PubMed]
  11. Attane C, Daviaud D, Dray C, et al. Apelin stimulates glucose uptake but not lipolysis in human adipose tissue ex vivo. J Mol Endocrinol 2011 ; 46 : 21–28. [CrossRef] [PubMed]
  12. Attane C, Foussal C, Le Gonidec S, et al. Apelin treatment increases complete fatty acid oxidation, mitochondrial oxidative capacity, and biogenesis in muscle of insulin-resistant mice. Diabetes 2012 ; 61 : 310–320. [CrossRef] [PubMed]
  13. Dray C, Sakar Y, Vinel C, et al. The intestinal glucose-apelin cycle controls carbohydrate absorption in mice. Gastroenterology 2013 ; 144 : 771–780. [CrossRef] [PubMed]
  14. Than A, Cheng Y, Foh LC, et al. Apelin inhibits adipogenesis and lipolysis through distinct molecular pathways. Mol Cell Endocrinol 2012 ; 362 : 227–241. [CrossRef] [PubMed]
  15. Lee DK, Ferguson SS, George SR, O’Dowd BF. The fate of the internalized apelin receptor is determined by different isoforms of apelin mediating differential interaction with beta-arrestin. Biochem Biophys Res Commun 2010 ; 395 : 185–189. [CrossRef] [PubMed]
  16. Zhou N, Fang J, Acheampong E, et al. Binding of ALX40-4C to APJ, a CNS-based receptor, inhibits its utilization as a co-receptor by HIV-1. Virology 2003 ; 312 : 196–203. [CrossRef] [PubMed]
  17. Scimia MC, Hurtado C, Ray S, et al. APJ acts as a dual receptor in cardiac hypertrophy. Nature 2012 ; 488 : 394–398. [CrossRef] [PubMed]
  18. Siddiquee K, Hampton J, McAnally D, et al. The apelin receptor inhibits the angiotensin II type 1 receptor via allosteric trans-inhibition. Br J Pharmacol 2013 ; 168 : 1104–1117. [CrossRef] [PubMed]
  19. Chun HJ, Ali ZA, Kojima Y, et al. Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis. J Clin Invest 2008 ; 118 : 3343–3354. [PubMed]
  20. Sun X, Iida S, Yoshikawa A, et al. Non-activated APJ suppresses the angiotensin II type 1 receptor, whereas apelin-activated APJ acts conversely. Hypertens Res 2011 ; 34 : 701–706. [CrossRef] [PubMed]
  21. Cheng SC, Ho L, Tian J, Reversade B. ELABELA: a hormone essential for heart development signals via the apelin receptor. Dev Cell 2013 ; 27 : 672–680. [CrossRef] [PubMed]
  22. Pauli A, Norris ML, Valen E, et al. Toddler: an embryonic signal that promotes cell movement via apelin receptors. Science 2014 ; 343 : 1248636. [CrossRef] [PubMed]
  23. Khan P, Maloney PR, Hedrick M, et al. Functional agonists of the apelin (APJ) receptor. Probe Reports from the NIH Molecular Libraries Program, Bethesda (MD), 2010.
  24. Macaluso NJ, Pitkin SL, Maguire JJ, et al. Discovery of a competitive apelin receptor (APJ) antagonist. Chem Med Chem 2011 ; 6 : 1017–1023. [CrossRef]
  25. Iturrioz X, Alvear-Perez R, De Mota N, et al. Identification and pharmacological properties of E339–3D6, the first nonpeptidic apelin receptor agonist. FASEB J 2010 ; 24 : 1506–1517. [CrossRef] [PubMed]
  26. Boucher J, Masri B, Daviaud D, et al. Apelin, a newly identified adipokine up-regulated by insulin and obesity. Endocrinology 2005 ; 146 : 1764–1771. [CrossRef] [PubMed]
  27. Sorhede Winzell M, Magnusson C, Ahren B. The apj receptor is expressed in pancreatic islets and its ligand, apelin, inhibits insulin secretion in mice. Regul Pept 2005; 131 : 12–17. [CrossRef] [PubMed]
  28. Ringstrom C, Nitert MD, Bennet H, et al. Apelin is a novel islet peptide. Regul Pept 2010 ; 162 : 44–51. [CrossRef] [PubMed]
  29. Duparc T, Colom A, Cani PD, et al. Central apelin controls glucose homeostasis via a nitric oxide-dependent pathway in mice. Antioxid Redox Signal 2011 ; 15 : 1477–1496. [CrossRef] [PubMed]
  30. Yue P, Jin H, Aillaud M, et al. Apelin is necessary for the maintenance of insulin sensitivity. Am J Physiol Endocrinol Metab 2010 ; 298 : E59–E67. [CrossRef] [PubMed]
  31. Xu S, Han P, Huang M, et al. In vivo, ex vivo, and in vitro studies on apelin’s effect on myocardial glucose uptake. Peptides 2012 ; 37 : 320–326. [CrossRef] [PubMed]
  32. Drougard A, Duparc T, Brenachot X, et al. Hypothalamic apelin/reactive oxygen species signaling controls hepatic glucose metabolism in the onset of diabetes. Antioxid Redox Signal 2014 ; 20 : 557–573. [CrossRef] [PubMed]
  33. Yamamoto T, Habata Y, Matsumoto Y, et al. Apelin-transgenic mice exhibit a resistance against diet-induced obesity by increasing vascular mass and mitochondrial biogenesis in skeletal muscle. Biochim Biophys Acta 2011 ; 1810 : 853–862. [CrossRef] [PubMed]
  34. Sawane M, Kajiya K, Kidoya H, et al. Apelin inhibits diet-induced obesity by enhancing lymphatic and blood vessel integrity. Diabetes 2013 ; 62 : 1970–1980. [CrossRef] [PubMed]
  35. Dray C, Debard C, Jager J, et al. Apelin and APJ regulation in adipose tissue and skeletal muscle of type 2 diabetic mice and humans. Am J Physiol Endocrinol Metab 2010 ; 298 : E1161–E1169. [CrossRef] [PubMed]
  36. Bertrand C, Pignalosa A, Wanecq E, et al. Effects of dietary eicosapentaenoic acid (EPA) supplementation in high-fat fed mice on lipid metabolism and apelin/APJ system in skeletal muscle. PLoS One 2013 ; 8 : e78874. [CrossRef] [PubMed]
  37. Castan-Laurell I, Vitkova M, Daviaud D, et al. Effect of hypocaloric diet-induced weight loss in obese women on plasma apelin and adipose tissue expression of apelin and APJ. Eur J Endocrinol 2008 ; 158 : 905–910. [CrossRef] [PubMed]
  38. Besse-Patin A, Montastier E, Vinel C, et al. Effect of endurance training on skeletal muscle myokine expression in obese men: identification of apelin as a novel myokine. Int J Obes (Lond) 2014 ; 38 : 707–713. [CrossRef] [PubMed]
  39. Kniazeff J, Pin JP. Des dimères et des oligomères de récepteurs couplés aux protéines G, oui mais pourquoi ?. Med sci (Paris) 2012 ; 10 : 858–864. [CrossRef] [EDP Sciences] [PubMed]

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