Vers un vaccin universel contre la grippe ?

Cyrille Dreyfus

doi:10.1051/medsci/2013291007

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Volume 29 / Numéro 1 (Janvier 2013)

Med Sci (Paris), 29 1 (2013) 22-25

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Numéro		Med Sci (Paris) Volume 29, Numéro 1, Janvier 2013


Page(s)		22 - 25
Section		Nouvelles
DOI		https://doi.org/10.1051/medsci/2013291007
Publié en ligne		25 janvier 2013

Burton DR, Poignard P, Stanfield RL, Wilson IA. Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses. Science 2012 ; 337 : 183–186. [CrossRef] [PubMed] [Google Scholar]
Corti D, Voss J, Gamblin ST, et al. A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins. Science 2011 ; 333 : 850–856. [CrossRef] [PubMed] [Google Scholar]
Dreyfus C, Laursen NS, Kwaks T, et al. Highly conserved protective epitopes on influenza B viruses. Science 2012 ; 337 : 1343–1348. [CrossRef] [PubMed] [Google Scholar]
Ekiert DC, Bhabha G, Elsliger MA, et al. Antibody recognition of a highly conserved influenza virus epitope. Science 2009 ; 324 : 246–251. [CrossRef] [PubMed] [Google Scholar]
Ekiert DC, Friesen RH, Bhabha G, et al. A highly conserved neutralizing epitope on group 2 influenza A viruses. Science 2011 ; 333 : 843–850. [CrossRef] [PubMed] [Google Scholar]
Sui J, Hwang WC, Perez S, et al. Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nat Struct Biol 2009 ; 16 : 265–273. [CrossRef] [Google Scholar]
McCullers JA, Saito T, Iverson AR. Multiple genotypes of influenza B virus circulated between 1979 and 2003. J Virol 2004 ; 78 : 12817–12828. [CrossRef] [PubMed] [Google Scholar]
Throsby M, van den Brink E, Jongeneelen M, et al. Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1, H1N1 recovered from human IgM⁺ memory B cells. PLoS One 2008 ; 3 : e3942. [CrossRef] [PubMed] [Google Scholar]
Thompson WW, Shay DK, Weintraub E, et al. Influenza-associated hospitalizations in the United States. JAMA 2004 ; 292 : 1333–1340. [CrossRef] [PubMed] [Google Scholar]
Gubareva LV, Kaiser L, Hayden FG. Influenza virus neuraminidase inhibitors. Lancet 2000 ; 355 : 827–835. [CrossRef] [PubMed] [Google Scholar]
Hessell AJ, Hangartner L, Hunter M, et al. Fc receptor but not complement binding is important in antibody protection against HIV. Nature 2007 ; 449 : 101–104. [CrossRef] [PubMed] [Google Scholar]
Fleishman SJ, Whitehead TA, Ekiert DC, et al. Computational design of proteins targeting the conserved stem region of influenza hemagglutinin. Science 2011 ; 332 : 816–821. [CrossRef] [PubMed] [Google Scholar]
Whitehead TA, Chevalier A, Song Y, et al. Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing. Nat Biotechnol 2012 ; 30 : 543–548. [CrossRef] [PubMed] [Google Scholar]
Bao Y, Bolotov P, Dernovoy D, et al. The influenza virus resource at the National Center for Biotechnology Information. J Virol 2008 ; 82 : 596–601. [CrossRef] [PubMed] [Google Scholar]

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[1] Burton DR, Poignard P, Stanfield RL, Wilson IA. Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses. Science 2012 ; 337 : 183–186. [CrossRef] [PubMed] [Google Scholar]

[2] Corti D, Voss J, Gamblin ST, et al. A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins. Science 2011 ; 333 : 850–856. [CrossRef] [PubMed] [Google Scholar]

[3] Dreyfus C, Laursen NS, Kwaks T, et al. Highly conserved protective epitopes on influenza B viruses. Science 2012 ; 337 : 1343–1348. [CrossRef] [PubMed] [Google Scholar]

[4] Ekiert DC, Bhabha G, Elsliger MA, et al. Antibody recognition of a highly conserved influenza virus epitope. Science 2009 ; 324 : 246–251. [CrossRef] [PubMed] [Google Scholar]

[5] Ekiert DC, Friesen RH, Bhabha G, et al. A highly conserved neutralizing epitope on group 2 influenza A viruses. Science 2011 ; 333 : 843–850. [CrossRef] [PubMed] [Google Scholar]

[6] Sui J, Hwang WC, Perez S, et al. Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nat Struct Biol 2009 ; 16 : 265–273. [CrossRef] [Google Scholar]

[7] McCullers JA, Saito T, Iverson AR. Multiple genotypes of influenza B virus circulated between 1979 and 2003. J Virol 2004 ; 78 : 12817–12828. [CrossRef] [PubMed] [Google Scholar]

[8] Throsby M, van den Brink E, Jongeneelen M, et al. Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1, H1N1 recovered from human IgM⁺ memory B cells. PLoS One 2008 ; 3 : e3942. [CrossRef] [PubMed] [Google Scholar]

[9] Thompson WW, Shay DK, Weintraub E, et al. Influenza-associated hospitalizations in the United States. JAMA 2004 ; 292 : 1333–1340. [CrossRef] [PubMed] [Google Scholar]

[10] Gubareva LV, Kaiser L, Hayden FG. Influenza virus neuraminidase inhibitors. Lancet 2000 ; 355 : 827–835. [CrossRef] [PubMed] [Google Scholar]

[11] Hessell AJ, Hangartner L, Hunter M, et al. Fc receptor but not complement binding is important in antibody protection against HIV. Nature 2007 ; 449 : 101–104. [CrossRef] [PubMed] [Google Scholar]

[12] Fleishman SJ, Whitehead TA, Ekiert DC, et al. Computational design of proteins targeting the conserved stem region of influenza hemagglutinin. Science 2011 ; 332 : 816–821. [CrossRef] [PubMed] [Google Scholar]

[13] Whitehead TA, Chevalier A, Song Y, et al. Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing. Nat Biotechnol 2012 ; 30 : 543–548. [CrossRef] [PubMed] [Google Scholar]

[14] Bao Y, Bolotov P, Dernovoy D, et al. The influenza virus resource at the National Center for Biotechnology Information. J Virol 2008 ; 82 : 596–601. [CrossRef] [PubMed] [Google Scholar]