Accès gratuit
Numéro
Med Sci (Paris)
Volume 27, Numéro 11, Novembre 2011
Page(s) 1025 - 1027
Section Prix Nobel 2011
DOI https://doi.org/10.1051/medsci/20112711021
Publié en ligne 30 novembre 2011
  1. Hoffmann JA, Levi C. Étude au microscope électronique du vaisseau dorsal de Locusta migratoria. CR Acad Sci Paris 1965 ; 260 : 6988–6990.
  2. Hoffmann JA, Stoeckel ME, Porte A, Joly P. Ultrastructure des hémocytes de Locusta migratoria. CR Acad Sci Paris 1968 ; 266 : 503–555.
  3. Hoffmann JA, Porte A, Joly P. Présence d’un tissu hématopoïétique au niveau du diaphragme dorsal de Locusta migratoria. CR Acad Sci Paris 1968 ; 267 : 1882–1883.
  4. Hoffmann JA. Régulations endocrines de la production et de la différenciation des hémocytes chez Locusta migratoria. Gen Comp Endocrinol 1970 ; 15 : 198–219. [CrossRef] [PubMed]
  5. Hoffmann JA. Effets d’une irradiation sélective du tissu hématopoiétique sur l’hémogramme d’imagos mâles de Locusta migratoria. CR Acad Sci Paris 1971 ; 273 : 1604–1607.
  6. Hoffmann JA. Modifications of the haemogramme of larval and adult grasshoppers (Locusta migratoria) after selective X-irradiations of the hemocytopoietic tissue. J Insect Physiol 1971 ; 18 : 1639–1652. [CrossRef]
  7. Butenandt A, Karlson P. Uber dies isolierung eines metamorphosehormons der insekten in kristallisierter form. Zeitschr Naturforsch 1954 ; B9 : 389–391.
  8. Hoffmann JA, Koolman J, Karlson P. Sulphate esters as inactivation products of ecdysone in Locusta migratoria. Z Physiol Chem 1973 ; 354 : 1043–1048. [CrossRef]
  9. Hoffmann JA, Koolman J, Karlson P, Joly P. Molting hormone titer and metabolic fate of injected ecdysone during the fifth larval instar and in adults of Locusta migratoria. Gen Comp Endocrinol 1974 ; 22 : 90–97. [CrossRef] [PubMed]
  10. Lagueux M, Hetru C, Luu B, Hoffmann JA. Adult ovaries of Locusta migratoria contain the sequence of biosynthetic intermediate for ecdysone. Life Sci 1978 ; 22 : 2141–2154. [CrossRef] [PubMed]
  11. Lagueux M, Harry P, Hoffmann JA. Ecdysteroids are bound to vitellin in newly-laid eggs of Locusta. Mol Cell Endocrinol 1981 ; 24 : 325–338. [CrossRef] [PubMed]
  12. Hetru C, Kappler C, Hoffmann JA, et al. The biosynthetic pathway of ecdysone: studies with vitellogenic ovaries of Locusta migratoria (Orthoptera). Mol Cell Endocrinol 1982 ; 26 : 51–80. [CrossRef] [PubMed]
  13. Tsoupras G, Luu B, Hoffmann JA. A cytokinin (isopentenyl-adenosyl-mononucleotide) is linked to ecdysone in newly-laid eggs of Locusta migratoria. Science 1983 ; 220 : 507–509. [CrossRef] [PubMed]
  14. Steiner H, Hultmark D, Engström A, et al. Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature 1981 ; 292 : 246–248. [CrossRef] [PubMed]
  15. Lambert J, Keppi E, Dimarcq JL, et al. Insect immunity. Isolation from immune blood of the Dipteran Phormia terranovae of two novel antibacterial peptides with sequence homology to rabbit lung macrophage bactericidal peptides. Proc Natl Acad Sci USA 1989 ; 86 : 262–266. [CrossRef]
  16. Dimarcq JL, Zachary D, Hoffmann JA, et al. Insect immunity. Expression of the two major inducible antibacterial peptides, defensin and diptericin, in Phormia terranovae. EMBO J 1990 ; 9 : 2507–2515. [PubMed]
  17. Reichhart JM, Meister M, Dimarcq JL, et al. Insect immunity. Developmental and inducible activity of the Drosophila diptericin promoter. EMBO J 1992 ; 11 : 1469–1477. [PubMed]
  18. Kapple C, Meister M, Lagueux M, et al. Insect immunity. Two 17-bp repeats nesting a κB-related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria-challenged Drosophila. EMBO J 1982 ; 12 : 1561–1568.
  19. Reichhart JM, Georgel P, Meister M, et al. Expression and nuclear translocation of the rel/NF-κB-related morphogen dorsal during the immune response of Drosophila. CR Acad Sci Paris 1993 ; 316 : 1218–1224.
  20. Lemaitre B, Meister M, Govind S, et al. Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila. EMBO J 1995 ; 14 : 536–545. [PubMed]
  21. Lemaitre B, Kromer-Metzger E, Michaut L, et al. A recessive mutation, immune-deficiency (imd), defines two distinct control pathways in the Drosophila host defense. Proc Natl Acad Sci USA 1995 ; 92 : 9465–9469. [CrossRef]
  22. Lemaitre B, Nicolas E, Michaut L, et al. The dorsoventral regulatory gene cassette spaetzle/toll/cactus controls the potent antifungal response in Drosophila adults. Cell 1996 ; 86 : 973–983. [CrossRef] [PubMed]
  23. Poltorak A, He X, Smirnova I, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998 ; 282 : 2085–2088. [CrossRef] [PubMed]
  24. Manfruelli P, Reichhart JM, Steward R, et al. A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins DORSAL and DIF. EMBO J 1999 ; 18 : 3380–3391. [CrossRef] [PubMed]
  25. Levashina E, Langley E, Green C, et al. Deficiency of a blood serpin leads to constitutive activation of the Toll-mediated antifungal defense in Drosophila. Science 1999 ; 285 : 1917–1919. [CrossRef] [PubMed]
  26. Hoffmann JA, Kafatos FC, Janeway CA Jr, Ezekowitz RAB. Phylogenetic perspectives in innate immunity. Science 1999 ; 284 : 1313–1318. [CrossRef] [PubMed]
  27. Franc N, Dimarcq JI, Lagueux M, et al. Croquemort, a novel Drosophila hemocyte/macrophage receptor that recognizes apoptotic cells. Immunity 1996 ; 4 : 431–443. [CrossRef] [PubMed]
  28. Ferrandon D, Jung AC, Criqui MC, et al. A GFP-drosomycin reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway. EMBO J 1998 ; 17 : 1217–1227. [CrossRef] [PubMed]
  29. Tauszig S, Jouanguy E, Hoffmann JA, Imler JL. Toll-related receptors and the control of antimicrobial peptide expression in Drosophila. Proc Natl Acad Sci USA 2000 ; 97 : 10520–10525. [CrossRef]
  30. Rutschmann S, Jung AC, Zhou R, et al. Role of Drosophila IKKg in a Toll-independent antibacterial immune response. Nat Immunol 2000 ; 1 : 342–347. [CrossRef] [PubMed]
  31. Michel T, Reichhart JM, Hoffmann JA, Royet J. Drosophila Toll is activated by Gram-positive bacteria via a circulating peptidoglycan recognition protein. Nature 2001 ; 414 : 756–759. [CrossRef] [PubMed]
  32. Gottar M, Gobert V, Michel T, et al. The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein. Nature 2002 ; 416 : 641–644. [CrossRef]
  33. Hoffmann JA, Reichhart JM. Drosophila immunity: an evolutionary perspective. Nat Immunol 2002 ; 3 : 121–126. [CrossRef] [PubMed]
  34. Ligoxygakis P, Pelte N, Hoffmann JA, Reichhart JM. Activation of Drosophila Toll during fungal infection by a novel blood serine protease. Science 2002 ; 297 : 114–116. [CrossRef] [PubMed]
  35. Hoffmann JA, Dimarcq JL, Bulet P. Les peptides antibactériens inductibles des insectes. Med Sci (Paris) 1992 ; 8 : 432–439. [CrossRef]
  36. Imler JL, Reichhart JM. Immunité innée : deux récepteurs pour détecter l’ADN bactérien. Med Sci (Paris) 2001 ; 17 : 510–512. [CrossRef]
  37. Blandin S, Levashina EA. Curing mosquitoes to control malaria? Med Sci (Paris) 2004 ; 20 : 740–742. [CrossRef] [EDP Sciences] [PubMed]

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