Biogénèse de la télomérase : un long voyage jusqu’au bout des chromosomes

Franck Gallardo; Pascal Chartrand

doi:10.1051/medsci/2009253232

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Volume 25 / Numéro 3 (Mars 2009)

Med Sci (Paris), 25 3 (2009) 232-233

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Numéro		Med Sci (Paris) Volume 25, Numéro 3, Mars 2009


Page(s)		232 - 233
Section		Nouvelles
DOI		https://doi.org/10.1051/medsci/2009253232
Publié en ligne		15 mars 2009

Vega LR, Mateyak MK, Zakian VA. Getting to the end: telomerase access in yeast and humans. Nat Rev Mol Cell Biol 2003; 4 : 948–59. [Google Scholar]
Harley CB. Telomerase and cancer therapeutics. Nat Rev Cancer 2008; 8 : 167–79. [Google Scholar]
Taggart AK, Teng SC, Zakian VA. Est1p as a cell cycle-regulated activator of telomere-bound telomerase. Science 2002; 297 : 1023–6. [Google Scholar]
Stellwagen AE, Haimberger ZW, Veatch JR, Gottschling DE. Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends. Genes Dev 2003; 17 : 2384–95. [Google Scholar]
Mozdy AD, Cech TR. Low abundance of telomerase in yeast: implications for telomerase haploinsufficiency. RNA 2006; 12 : 1721–37. [Google Scholar]
Ferrezuelo F, Steiner B, Aldea M, Futcher B. Biogenesis of yeast telomerase depends on the importin mtr10. Mol Cell Biol 2002; 22 : 6046–55. [Google Scholar]
Teixeira MT, Forstemann K, Gasser SM, Lingner J. Intracellular trafficking of yeast telomerase components. EMBO Rep 2002; 3 : 652–9. [Google Scholar]
Gallardo F, Olivier C, Dandjinou AT, et al. TLC1 RNA nucleo-cytoplasmic trafficking links telomerase biogenesis to its recruitment to telomeres. EMBO J 2008; 27 : 748–57. [Google Scholar]
Jady BE, Bertrand E, Kiss T. Human telomerase RNA and box H/ACA scaRNAs share a common Cajal body-specific localization signal. J Cell Biol 2004; 164 : 647–52. [Google Scholar]
Zhu Y, Tomlinson RL, Lukowiak AA, et al. Telomerase RNA Accumulates in Cajal Bodies in Human Cancer Cells. Mol Biol Cell 2004; 15 : 81–90. [Google Scholar]
Cristofari G, Adolf E, Reichenbach P, et al. Human Telomerase RNA Accumulation in Cajal Bodies Facilitates Telomerase Recruitment to Telomeres and Telomere Elongation. Mol Cell 2007; 27 : 882–9. [Google Scholar]

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[1] Vega LR, Mateyak MK, Zakian VA. Getting to the end: telomerase access in yeast and humans. Nat Rev Mol Cell Biol 2003; 4 : 948–59. [Google Scholar]

[2] Harley CB. Telomerase and cancer therapeutics. Nat Rev Cancer 2008; 8 : 167–79. [Google Scholar]

[3] Taggart AK, Teng SC, Zakian VA. Est1p as a cell cycle-regulated activator of telomere-bound telomerase. Science 2002; 297 : 1023–6. [Google Scholar]

[4] Stellwagen AE, Haimberger ZW, Veatch JR, Gottschling DE. Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends. Genes Dev 2003; 17 : 2384–95. [Google Scholar]

[5] Mozdy AD, Cech TR. Low abundance of telomerase in yeast: implications for telomerase haploinsufficiency. RNA 2006; 12 : 1721–37. [Google Scholar]

[6] Ferrezuelo F, Steiner B, Aldea M, Futcher B. Biogenesis of yeast telomerase depends on the importin mtr10. Mol Cell Biol 2002; 22 : 6046–55. [Google Scholar]

[7] Teixeira MT, Forstemann K, Gasser SM, Lingner J. Intracellular trafficking of yeast telomerase components. EMBO Rep 2002; 3 : 652–9. [Google Scholar]

[8] Gallardo F, Olivier C, Dandjinou AT, et al. TLC1 RNA nucleo-cytoplasmic trafficking links telomerase biogenesis to its recruitment to telomeres. EMBO J 2008; 27 : 748–57. [Google Scholar]

[9] Jady BE, Bertrand E, Kiss T. Human telomerase RNA and box H/ACA scaRNAs share a common Cajal body-specific localization signal. J Cell Biol 2004; 164 : 647–52. [Google Scholar]

[10] Zhu Y, Tomlinson RL, Lukowiak AA, et al. Telomerase RNA Accumulates in Cajal Bodies in Human Cancer Cells. Mol Biol Cell 2004; 15 : 81–90. [Google Scholar]

[11] Cristofari G, Adolf E, Reichenbach P, et al. Human Telomerase RNA Accumulation in Cajal Bodies Facilitates Telomerase Recruitment to Telomeres and Telomere Elongation. Mol Cell 2007; 27 : 882–9. [Google Scholar]