Accès gratuit
Numéro
Med Sci (Paris)
Volume 22, Numéro 5, Mai 2006
Page(s) 537 - 543
Section M/S revues
DOI https://doi.org/10.1051/medsci/2006225537
Publié en ligne 15 mai 2006
  1. Krupnick JG, Benovic JL. The role of receptor kinases and arrestins in G protein-coupled receptor regulation. Annu Rev Pharmacol Toxicol 1998; 38 : 289–319.
  2. Lefkowitz RJ, Shenoy SK. Transduction of receptor signals by beta-arrestins. Science 2005; 308 : 512–7.
  3. Metaye T, Gibelin H, Perdrisot R, Kraimps JL. Pathophysiological roles of G-protein-coupled receptor kinases. Cell Signal 2005; 17 : 917–28.
  4. Chen J, Simon MI, Matthes MT, et al. Increased susceptibility to light damage in an arrestin knockout mouse model of Oguchi disease (stationary night blindness). Invest Ophthalmol Vis Sci 1999; 40 : 2978–82.
  5. Chen CK, Burns ME, Spencer M, et al.Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase. Proc Natl Acad Sci USA 1999; 96 : 3718–22.
  6. Fuchs S, Nakazawa M, Maw M, et al.A homozygous 1-base pair deletion in the arrestin gene is a frequent cause of Oguchi disease in Japanese. Nat Genet 1995; 10 : 360–2.
  7. Yamamoto S, Sippel KC, Berson EL, Dryja TP. Defects in the rhodopsin kinase gene in the Oguchi form of stationary night blindness. Nat Genet 1997; 15 : 175–8.
  8. Ungerer M, Bohm M, Elce JS, et al.Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart. Circulation 1993; 87 : 454–63.
  9. Gros R, Benovic JL, Tan CM, Feldman RD. G-protein-coupled receptor kinase activity is increased in hypertension. J Clin Invest 1997; 99 : 2087–93.
  10. Mak JC, Chuang TT, Harris CA, Barnes PJ. Increased expression of G protein-coupled receptor kinases in cystic fibrosis lung. Eur J Pharmacol 2002; 436 : 165–72.
  11. Eckhart AD, Ozaki T, Tevaearai H, et al.Vascular-targeted overexpression of G protein-coupled receptor kinase-2 in transgenic mice attenuates beta-adrenergic receptor signaling and increases resting blood pressure. Mol Pharmacol 2002; 61 : 749–58.
  12. Dinudon A, Fotia AB, Lefkowitz RJ, et al.The kinase GRK2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na+ channels. Proc Natl Acad Sci USA 2004; 101 : 11886–90.
  13. Lombardi MS, Kavelaars A, Schedlowski M, et al.Decreased expression and activity of G-protein-coupled receptor kinases in peripheral blood mononuclear cells of patients with rheumatoid arthritis. FASEB J 1999; 13 : 715–25.
  14. Lombardi MS, Kavelaars A, Cobelens PM, et al.Adjuvant arthritis induces down-regulation of G protein-coupled receptor kinases in the immune system. J Immunol 2001; 166 : 1635–40.
  15. Vroon A, Heijnen CJ, Lombardi MS, et al.Reduced GRK2 level in T cells potentiates chemotaxis and signaling in response to CCL4. J Leukoc Biol 204; 75 : 901–9.
  16. Vroon A, Heijnen CJ, Raatgever R, et al.GRK6 deficiency is associated with enhanced CXCR4-mediated neutrophil chemotaxis in vitro and impaired responsiveness to G-CSF in vivo. J Leukoc Biol 2004; 75 : 698–704.
  17. Felder RA, Sanada H, Xu J, et al.G protein-coupled receptor kinase 4 gene variants in human essential hypertension. Proc Natl Acad Sci USA 2002; 99 : 3872–7.
  18. Speirs HJ, Katyk K, Kumar NN, et al.Association of G-protein-coupled receptor kinase 4 haplotypes, but not HSD3B1 or PTP1B polymorphisms, with essential hypertension. J Hypertens 2004; 22 : 931–6.
  19. Bezard E, Gross CE, Qin L, et al.L-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain. Neurobiol Dis 2005; 18 : 323–35.
  20. Garcia-Sevilla JA, Escriba PV, Ozaita A, et al.Up-regulation of immunolabeled alpha2A-adrenoceptors, Gi coupling proteins, and regulatory receptor kinases in the prefrontal cortex of depressed suicides. J Neurochem 1999; 72 : 282–91.
  21. Grange-Midroit M, Garcia-Sevilla JA, Ferrer-Alcon M, et al.Regulation of GRK 2 and 6, beta-arrestin-2 and associated proteins in the prefrontal cortex of drug-free and antidepressant drug-treated subjects with major depression. Brain Res Mol Brain Res 2003; 111 : 31–41.
  22. Avissar S, Matuzany-Ruban A, Tzukert K, Schreiber G. Beta-arrestin-1 levels : reduced in leukocytes of patients with depression and elevated by antidepressants in rat brain. Am J Psychiatry 2004; 161 : 2066–72.
  23. Matuzany-Ruban A, Avissar S, Schreiber G. Dynamics of beta-arrestin1 protein and mRNA levels elevation by antidepressants in mononuclear leukocytes of patients with depression. J Affect Disord 2005; 88 : 307–12.
  24. Ferrer-Alcon M, La Harpe R, Garcia-Sevilla JA. Decreased immunodensities of micro-opioid receptors, receptor kinases GRK 2/6 and beta-arrestin-2 in postmortem brains of opiate addicts. Brain Res Mol Brain Res 2004; 121 : 114–22.
  25. Bohn LM, Gainetdinov RR, Lin FT, et al.Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence. Nature 2000; 408 : 720–3.
  26. Terman GW, Jin W, Cheong YP, et al.G-protein receptor kinase 3 (GRK3) influences opioid analgesic tolerance but not opioid withdrawal. Br J Pharmacol 2004; 141 : 55–64.
  27. Xu M, Petraschka M, McLaughlin JP, et al.Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance. J Neurosci 2004; 24 : 4576–84.
  28. King DW, Steinmetz R, Wagoner HA, et al.Differential expression of GRK isoforms in nonmalignant and malignant human granulosa cells. Endocrine 2003; 22 : 135–42.
  29. Metaye T, Menet E, Guilhot J, Kraimps JL. Expression and activity of G protein-coupled receptor kinases in differentiated thyroid carcinoma. J Clin Endocrinol Metab 2002; 87 : 3279–86.
  30. Iacovelli L, Capobianco L, D’Ancona GM, et al.Regulation of lysophosphatidic acid receptor-stimulated response by G-protein-coupled receptor kinase-2 and beta-arrestin1 in FRTL-5 rat thyroid cells. J Endocrinol 2002; 174 : 103–10.
  31. Bookout AL, Finney AE, Guo R, et al.Targeting Gbetagamma signaling to inhibit prostate tumor formation and growth. J Biol Chem 2003; 278 : 37569–73.
  32. Voigt C, Holzapfel H-P, Paschke R. Expression of b-arrestins in toxic and cold thyroid nodules. FEBS Lett 2000; 486 : 208–12.
  33. Rockman HA, Chien KR, Choi DJ, et al.Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice. Proc Natl Acad Sci USA 1998; 95 : 7000–5.
  34. White DC, Hata JA, Shah AS, et al. Preservation of myocardial b-edrenergic receptor signaling delays the development of heart failure after myocardial infarction. Proc Natl Acad Sci USA 2000; 97 : 5428–33.
  35. Vroon A, Kavelaars A, Limmroth V, et al.G protein-coupled receptor kinase 2 in multiple sclerosis and experimental autoimmune encephalomyelitis. J Immunol 2005; 174 : 4400–6.
  36. Anis Y, Leshem O, Reuveni H, et al.Antidiabetic effect of novel modulating peptides of G-protein-coupled kinase in experimental models of diabetes. Diabetologia 2004; 47 : 1232–44.
  37. Walker JK, Fong AM, Lawson BL, et al.Beta-arrestin-2 regulates the development of allergic asthma. J Clin Invest 2003; 112 : 566–74.
  38. Fong AM, Premont RT, Richardson RM, et al.Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice. Proc Natl Acad Sci USA 2002; 99 : 7478–83.
  39. Sun Y, Cheng Z, Ma L, Pei G. Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation. J Biol Chem 2002; 277 : 49212–9.

Les statistiques affichées correspondent au cumul d'une part des vues des résumés de l'article et d'autre part des vues et téléchargements de l'article plein-texte (PDF, Full-HTML, ePub... selon les formats disponibles) sur la platefome Vision4Press.

Les statistiques sont disponibles avec un délai de 48 à 96 heures et sont mises à jour quotidiennement en semaine.

Le chargement des statistiques peut être long.