Free Access
Med Sci (Paris)
Volume 22, Number 5, Mai 2006
Page(s) 531 - 536
Section M/S revues
Published online 15 May 2006
  1. Dworkin MS, Williamson JM. Adult/adolescent spectrum of HIV disease project. AIDS wasting syndrome : trends, influence on opportunistic infections, and survival. J Acquir Immune Defic Syndr 2003; 33 : 267–73. [Google Scholar]
  2. Jain RG, Furfine ES, Pedneault L, et al. Metabolic complications associated with antiretroviral therapy. Antiviral Res 2001; 51 : 151–77. [Google Scholar]
  3. Grinspoon S, Carr A. Cardiovascular risk and body-fat abnormalities in HIV-infected adults. N Engl J Med 2005; 352 : 48–62. [Google Scholar]
  4. Mattison RE, Jensen M. The adipocyte as an endocrine cell. Curr Opin Endocrinol Diabetes 2003; 10 : 317–21. [Google Scholar]
  5. Gougeon ML, Penicaud L, Fromenty B, et al. Adipocytes targets and actors in the pathogenesis of HIV-associated lipodystrophy and metabolic alterations. Antivir Ther 2004; 9 : 161–77. [Google Scholar]
  6. Nolan D, Mallal S. Complications associated with NRTI therapy : update on clinical features and possible pathogenic mechanisms. Antivir Ther 2004; 9 : 849–63. [Google Scholar]
  7. Caron M, Auclair M, Lagathu C, et al. HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro. AIDS 2004; 18 : 2127–36. [Google Scholar]
  8. Lagathu C, Bastard JP, Auclair M, et al. Antiretroviral drugs with adverse effects on adipocyte lipid metabolism and survival alter the expression and secretion of proinflammatory cytokines and adiponectin in vitro. Antivir Ther 2004; 9 : 911–20. [Google Scholar]
  9. Lagathu C, Kim M, Maachi M, et al. HIV antiretroviral treatment alters adipokine expression and insulin sensitivity of adipose tissue in vitro and in vivo. Biochimie 2005; 87 : 65–71. [Google Scholar]
  10. Mallon PW, Unemori P, Sedwell R, et al. In vivo, nucleoside reverse-transcriptase inhibitors alter expression of both mitochondrial and lipid metabolism genes in the absence of depletion of mitochondrial DNA. J Infect Dis 2005; 191 : 1686–96. [Google Scholar]
  11. Dowell P, Flexner C, Kwiterovich PO, Lane MD. Suppression of preadipocyte differentiation and promotion of adipocyte death by HIV protease inhibitors. J Biol Chem 2000; 275 : 41325–32. [Google Scholar]
  12. Caron M, Auclair M, Vigouroux C, et al. The HIV protease inhibitor indinavir impairs sterol regulatory element-binding protein-1 intranuclear localization, inhibits preadipocyte differentiation, and induces insulin resistance. Diabetes 2001; 50 : 1378–88. [Google Scholar]
  13. Caron M, Auclair M, Sterlingot H, et al. Some HIV protease inhibitors alter lamin A/C maturation and stability, SREBP-1 nuclear localization and adipocyte differentiation. AIDS 2003; 17 : 2437–44. [Google Scholar]
  14. Vigouroux C. Laminopathies : lipodystrophies, insulin resistance, syndromes of accelerated ageing… and others. Ann Endocrinol (Paris) 2005; 66 : 270–8. [Google Scholar]
  15. Liu B, Wang J, Chan KM, et al. Genomic instability in laminopathy-based premature aging. Nat Med 2005; 11 : 780–5. [Google Scholar]
  16. Varela I, Cadinanos J, Pendas AM, et al. Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation. Nature 2005; 437 : 564–8. [Google Scholar]
  17. Hadri KE, Glorian M, Monsempes C, et al. In vitro suppression of the lipogenic pathway by the nonnucleoside reverse transcriptase inhibitor efavirenz in 3T3 and human preadipocytes or adipocytes. J Biol Chem 2004; 279 : 15130–41. [Google Scholar]
  18. McComsey GA, Ward DJ, Hessenthaler SM, et al. Trial to assess the regression of hyperlactatemia and to evaluate the regression of established lipodystrophy in HIV-1-positive subjects (TARHEEL ; ESS40010) study team. Improvement in lipoatrophy associated with highly active antiretroviral therapy in human immunodeficiency virus-infected patients switched from stavudine to abacavir or zidovudine : the results of the TARHEEL study. Clin Infect Dis 2004; 38 : 263–70. [Google Scholar]
  19. Martin A, Smith DE, Carr A, et al. Mitochondrial Toxicity Study Group. Reversibility of lipoatrophy in HIV-infected patients 2 years after switching from a thymidine analogue to abacavir : the MITOX Extension Study. AIDS 2004; 18 : 1029–36. [Google Scholar]
  20. Domingo P, Matias-Guiu X, Pujol RM, et al. Subcutaneous adipocyte apoptosis in HIV-1 protease inhibitor-associated lipodystrophy. AIDS 1999; 13 : 2261–7. [Google Scholar]
  21. Nolan D, Hammond E, Martin A, et al. Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy. AIDS 2003; 17 : 1329–38. [Google Scholar]
  22. Jan V, Cervera P, Maachi M, et al. Altered fat differentiation and adipocytokine expression are inter-related and linked to morphological changes and insulin resistance in HIV-1-infected lipodystrophic patients. Antivir Ther 2004; 9 : 555–64. [Google Scholar]
  23. Weisberg SP, McCann D, Desai M, et al. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003; 112 : 1796–808. [Google Scholar]
  24. Cancello R, Henegar C, Viguerie N, et al. Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss. Diabetes 2005; 54 : 2277–86. [Google Scholar]
  25. Bastard JP, Caron M, Vidal H, et al.Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose tissue from HIV-1-infected patients and abnormal adipocyte differentiation and insulin resistance. Lancet 2002; 359 : 1026–31. [Google Scholar]
  26. Hammond E, Nolan D, McKinnon E, et al.Assessing the contribution of ART, HIV and host factors to changes occurring in adipose tissue of HIV-infected individuals : risk profile for lipoatrophy. Antivir Ther 2005; 10(suppl 3) : L4. [Google Scholar]
  27. Stulnig TM, Waldhausl W. 11beta-Hydroxysteroid dehydrogenase Type 1 in obesity and Type 2 diabetes. Diabetologia 2004; 47 : 1–11. [Google Scholar]
  28. Bujalska IJ, Kumar S, Hewison M, Stewart PM. Differentiation of adipose stromal cells : the roles of glucocorticoids and 11-hydroxysteroid dehydrogenase. J Clin Endocrinol Metab 1999; 140 : 3189–96. [Google Scholar]
  29. Bazuine M, Carlotti F, Tafrechi RS, et al.Mitogen-activated protein kinase (MAPK) phosphatase-1 and -4 attenuate p38 MAPK during dexamethasone-induced insulin resistance in 3T3-L1 adipocytes. Mol Endocrinol 2004; 18 : 1697–707. [Google Scholar]
  30. Degawa-Yamauchi M, Moss KA, Bovenkerk JE, et al.Regulation of adiponectin expression in human adipocytes : effects of adiposity, glucocorticoids, and tumor necrosis factor alpha. Obes Res 2005; 13 : 662–9. [Google Scholar]
  31. Trujillo ME, Lee MJ, Sullivan S, et al.Tumor necrosis factor (alpha) and glucocorticoid synergistically increase leptin production in human adipose tissue : role for p38 MAPK. J Clin Endocrinol Metab 2006; 10 janvier : online. [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.