EDP Sciences logo
Authentification abonné
Rechercher
Menu
Accueil Tous les numéros Volume 17 / Numéro 11 (Novembre 2001) Med Sci (Paris), 17 11 (2001) 1139-1148 Références
Accès gratuit
Numéro
Med Sci (Paris)
Volume 17, Numéro 11, Novembre 2001
Page(s) 1139 - 1148
Section Articles de Synthèse
DOI https://doi.org/10.1051/medsci/200117111139
Publié en ligne 15 novembre 2001
  1. Falconner D. The inheritance of liability to certain diseases. Ann Hum Genet 1965; 29: 51–76. [Google Scholar]
  2. Lander ES, Schork NJ. Genetic dissection of complex traits. Science 1994; 265: 2037- 46. [Google Scholar]
  3. Clerget-Darpoux F, Bonaïti-Pellié C, Hochez J. Effects of misspecifying genetic parameters in lod score analysis. Biometrics 1986; 42: 393–9. [Google Scholar]
  4. Risch N. Linkage strategies for genetically complex traits. Am J Hum Genet 1990; 46: 229–41. [Google Scholar]
  5. Risch N, Merikangas K. Genetic analysis of complex diseases. Science 1997; 275: 1327–30. [Google Scholar]
  6. Myers A, Holmans P, Marshall H, et al. Susceptibility locus for Alzheimer’s disease on chromosome 10. Science 2000; 290: 2304–5. [Google Scholar]
  7. Spielman RS, Ewens WJ. A sibship based test for linkage in the presence of association : the sib transmission/disequilibrium test. Am J Hum Genet 1998; 62: 450–8. [Google Scholar]
  8. Feingold J. Le déséquilibre de liaison. Med Sci 1991; 7: 161–8. [Google Scholar]
  9. Laan M, Pääbo S. Mapping genes by driftgenerated linkage disequilibrium. Am J Hum Genet 1998; 63: 654–6. [Google Scholar]
  10. Wright A, Carothers A, Pirastu M. Population choice in mapping genes for complex diseases. Nat Genet 1999; 23: 397–403. [Google Scholar]
  11. Kruglyak L. Prospects for whole-genome linkage disequilibrium mapping of common disease genes. Nat Genet 1999; 22: 139–44. [Google Scholar]
  12. Pfaff C, Parra E, Bonilla C, et al. Population structure in admixed populations : effect of admixture dynamics on the pattern of linkage disequilibrium. Am J Hum Genet 2001; 68: 198–207. [Google Scholar]
  13. Boehnke M. A look at linkage disequilibrium. Nat Genet 2000; 25: 246–7. [Google Scholar]
  14. Schellenberg GD, Deeb SS, Boehnke M, et al. Association of an apolipoprotein CII allele with familial dementia of the Alzheimer type. J Neurogenet 1987; 4: 97–108. [Google Scholar]
  15. Yu C, Payami H, Olson JM, et al. The apolipoprotein E/CI/CII gene cluster and late-onset Alzheimer disease. Am J Hum Genet 1994; 54: 631–42. [Google Scholar]
  16. Strittmatter WJ, Roses AD. Apolipoprotein E and Alzheimer’s disease. Proc Natl Acad Sci USA 1995; 92: 4725–7. [Google Scholar]
  17. Pericak-Vance MA, Bebout JL, Gaskell PC, et al. Linkage studies in familial Alzheimer disease : evidence for chromosome 19 linkage. Am J Hum Genet 1991; 48: 1034–50. [Google Scholar]
  18. Bickeböller H, Campion D, Brice A, et al. Apolipoprotein E and Alzheimer disease: genotype-specific risks by age and sex. Am J Hum Genet 1997; 60: 439–46. [Google Scholar]
  19. Gray IC, Campbell DA, Spurr NK. Single nucleotide polymorphisms as tools in human genetics. Hum Mol Genet 2000; 9: 2403–8. [Google Scholar]
  20. Cargill M, Altshuler D, Ireland J, et al. Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat Genet 1999; 22: 231–8. [Google Scholar]
  21. Risch N, Merikangas K. The future of genetic studies of complex human diseases. Science 1996; 273: 1516–7. [Google Scholar]
  22. Collins FS, Guyer MS, Chakravarti A. Variations on a theme : cataloging human DNA sequence variation. Science 1997; 278: 1580–1. [Google Scholar]
  23. Jorde LB. Linkage disequilibrium as a gene mapping tool. Am J Hum Genet 1994; 52:362–74 [Google Scholar]
  24. Martin RE, Lai EH, Gilbert J, et al. SNPing away at complex diseases : analysis of single-nucleotide polymorphisms around APOE in Alzheimer’s disease. Am J Hum Genet 2000; 67: 383–94. [Google Scholar]
  25. Lander E, Kruglyak L. Genetic dissection of complex traits : guidelines for interpreting and reporting linkage results. Nat Genet 1995; 11: 241–7. [Google Scholar]
  26. Dipple KM, McCabe ERB. Phenotypes of patients with « simple » mendelian disorders are complex traits : thresholds, modifiers, and systems dynamics. Am J Hum.Genet 2000; 66: 1729–35. [Google Scholar]
  27. Estivill X. Complexity in a monogenic disease. Nat Genet 1996; 12: 348–50. [Google Scholar]
  28. Lander E, Botstein D. Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 1989; 121 : 185–99. [Google Scholar]
  29. Nadeau J, Frankel W. The roads from phenotypic variation to gene discovery : mutagenesis versus QTL. Nat Genet 2000; 25: 381–4. [Google Scholar]
  30. Peyron C, Faraco J, Rogers W, et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat Med 2000; 6: 991–7. [Google Scholar]
  31. Heutink P. Untangling tau-related dementia. Hum Mol Genet 2000; 9: 979–86. [Google Scholar]
  32. Siegel C, Waldo M, Mizner G, Adler L, Freedman R Deficit in sensory gating in schizophrenic patients and their relatives. Arch Gen Psychiatry 1984; 41: 607–12. [Google Scholar]
  33. Leonard S, Adams C, Breese CR, et al. Nicotinic receptor function in schizophrenia. Schizophrenia Bull 1996; 22: 431–45. [Google Scholar]
  34. Risch N. Searching for genetic determinants in the new millennium. Nature 2000; 405: 847–56. [Google Scholar]
  35. Weiss KM, Terwilliger JD. How many diseases does it take to map a gene with SNP? Nat Genet 2000; 26: 151–7. [Google Scholar]

Les statistiques affichées correspondent au cumul d'une part des vues des résumés de l'article et d'autre part des vues et téléchargements de l'article plein-texte (PDF, Full-HTML, ePub... selon les formats disponibles) sur la platefome Vision4Press.

Les statistiques sont disponibles avec un délai de 48 à 96 heures et sont mises à jour quotidiennement en semaine.

Le chargement des statistiques peut être long.