Open Access
Issue
Med Sci (Paris)
Volume 40, Number 3, Mars 2024
Page(s) 275 - 282
Section M/S Revues
DOI https://doi.org/10.1051/medsci/2024011
Published online 22 March 2024
  1. Hayflick L.. The limited in vitro lifetime of human diploid cell strains. Exp Cell Res 1965 ; 37 : 614–636. [CrossRef] [PubMed] [Google Scholar]
  2. Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res 1961 ; 25 : 585–621. [CrossRef] [PubMed] [Google Scholar]
  3. Ramirez RD, Morales CP, Herbert BS, et al. Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions. Genes Dev 2001 ; 15 : 398–403. [CrossRef] [PubMed] [Google Scholar]
  4. Chaib S, Tchkonia T, Kirkland JL. Cellular senescence and senolytics : the path to the clinic. Nat Med 2022; 28 : 1 556–68. [Google Scholar]
  5. Calcinotto A, Kohli J, Zagato E, et al. Cellular Senescence : Aging, Cancer, and Injury. Physiol Rev 2019 ; 99(1): 047–078. [Google Scholar]
  6. Bousset L, Gil J. Targeting senescence as an anticancer therapy. Mol Oncol 2022; 16 : 3 855–80. [Google Scholar]
  7. Abbadie C, Pluquet O, Pourtier A. Epithelial cell senescence : an adaptive response to pre-carcinogenic stresses ?. Cell Mol Life Sci 2017 ; 74 : 4471–4509. [CrossRef] [PubMed] [Google Scholar]
  8. Pluquet O, Pourtier A, Abbadie C. The unfolded protein response and cellular senescence. A review in the theme : cellular mechanisms of endoplasmic reticulum stress signaling in health and disease. Am J Physiol Cell Physiol 2014 ; 308 : C415–C425. [Google Scholar]
  9. Malaquin N, Martinez A, Rodier F. Keeping the senescence secretome under control : Molecular reins on the senescence-associated secretory phenotype. Exp Gerontol 2016 ; 82 : 39–49. [CrossRef] [PubMed] [Google Scholar]
  10. Di Micco R, Krizhanovsky V, Baker D, et al. Cellular senescence in ageing : from mechanisms to therapeutic opportunities. Nat Rev Mol Cell Biol 2021; 22 : 75–95. [CrossRef] [PubMed] [Google Scholar]
  11. Hu L, Li H, Zi M, et al. Why Senescent Cells Are Resistant to Apoptosis : An Insight for Senolytic Development. Front Cell Dev Biol 2022; 10 : 822 816. [CrossRef] [Google Scholar]
  12. Gao J, Pickett HA. Targeting telomeres : advances in telomere maintenance mechanism-specific cancer therapies. Nat Rev Cancer 2022; 22 : 515–32. [CrossRef] [PubMed] [Google Scholar]
  13. Goy E, Abbadie C. Sénescence et cancer : double jeu. Med Sci (Paris) 2018 ; 34 : 223–230. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  14. Hernandez-Segura A, Nehme J, Demaria M. Hallmarks of Cellular Senescence. Trends Cell Biol 2018 ; 28 : 436–453. [CrossRef] [Google Scholar]
  15. Gosselin K, Deruy E, Martien S, et al. Senescent keratinocytes die by autophagic programmed cell death. Am J Pathol 2009 ; 174 : 423–435. [CrossRef] [PubMed] [Google Scholar]
  16. Deruy E, Gosselin K, Vercamer C, et al. MnSOD upregulation induces autophagic programmed cell death in senescent keratinocytes. PLoS One 2010 ; 5 : e12712. [Google Scholar]
  17. Deruy E, Nassour J, Martin N, et al. Level of macroautophagy drives senescent keratinocytes into cell death or neoplastic evasion. Cell Death Dis 2014 ; 5 : e1577. [CrossRef] [PubMed] [Google Scholar]
  18. Nassour J, Martien S, Martin N, et al. Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells. Nat Commun 2016 ; 7(10): 399. [CrossRef] [Google Scholar]
  19. Goy E, Tomezak M, Facchin C, et al. The out-of-field dose in radiation therapy induces delayed tumorigenesis by senescence evasion. eLife 2022; 11 : e67190. [CrossRef] [PubMed] [Google Scholar]
  20. Goy E, Martin N, Drullion C, et al. Flow Cytometry-based Method for Efficient Sorting of Senescent Cells. BIO-Protoc. 2023; 13. [Google Scholar]
  21. Flor AC, Doshi AP, Kron SJ. Modulation of therapy-induced senescence by reactive lipid aldehydes. Cell Death Discov 2016 ; 2(16): 045. [Google Scholar]
  22. Debacq-Chainiaux F, Erusalimsky JD, Campisi J, et al. Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo. Nat Protoc 2009 ; 4(1): 798–806. [Google Scholar]
  23. Kim KM, Noh JH, Bodogai M, et al. Identification of senescent cell surface targetable protein DPP4. Genes Dev 2017 ; 31 : 1529–1534. [CrossRef] [PubMed] [Google Scholar]
  24. Admasu TD, Kim K, Rae M, et al. Selective ablation of primary and paracrine senescent cells by targeting iron dyshomeostasis. Cell Rep 2023; 42 : 112058. [CrossRef] [PubMed] [Google Scholar]
  25. Verhulst E, Garnier D, De Meester I, et al. Validating Cell Surface Proteases as Drug Targets for Cancer Therapy : What Do We Know, and Where Do We Go ? Cancers 2022; 14 : 624. [CrossRef] [PubMed] [Google Scholar]
  26. Greenberg SB, Grove GL, Cristofalo VJ. Cell size in aging monolayer cultures. In Vitro 1977 ; 13 : 297–300. [CrossRef] [PubMed] [Google Scholar]
  27. Terman A, Brunk UT. Oxidative Stress, Accumulation of Biological “Garbage”, and Aging. Antioxid Redox Signal 2006 ; 8 : 197–204. [CrossRef] [PubMed] [Google Scholar]
  28. Yin D.. Biochemical basis of lipofuscin, ceroid, and age pigment-like fluorophores. Free Radic Biol Med 1996 ; 21 : 871–888. [CrossRef] [PubMed] [Google Scholar]
  29. Pantelis P, Theocharous G, Lagopati N, et al. The Dual Role of Oxidative-Stress-Induced Autophagy in Cellular Senescence : Comprehension and Therapeutic Approaches. Antioxidants 2023; 12 : 169. [CrossRef] [PubMed] [Google Scholar]
  30. Gosselin K, Martien S, Pourtier A, et al. Senescence-associated oxidative DNA damage promotes the generation of neoplastic cells. Cancer Res 2009 ; 69 : 7917–7925. [CrossRef] [PubMed] [Google Scholar]
  31. Bernard D, Gosselin K, Monte D, et al. Involvement of Rel/NF-kappaB transcription factors in keratinocyte senescence. Cancer Res 2004 ; 64 : 472–481. [CrossRef] [PubMed] [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.