Free Access
Issue
Med Sci (Paris)
Volume 32, Number 6-7, Juin–Juillet 2016
Page(s) 574 - 578
Section Nouvelles
DOI https://doi.org/10.1051/medsci/20163206016
Published online 12 July 2016
  1. Dompmartin A, Vikkula M, Boon LM. Venous malformation: update on aetiopathogenesis, diagnosis and management. Phlebology 2010 ; 25 : 224–235. [CrossRef] [PubMed] [Google Scholar]
  2. Suri C, Jones PF, Patan S, et al. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 1996 ; 87 : 1171–1180. [PubMed] [Google Scholar]
  3. Laplante M, Sabatini DM. mTOR signaling in growth control and disease. Cell 2012 ; 149 : 274–293. [CrossRef] [PubMed] [Google Scholar]
  4. Korpelainen EI, Karkkainen M, Gunji Y, et al. Endothelial receptor tyrosine kinases activate the STAT signaling pathway: mutant Tie-2 causing venous malformations signals a distinct STAT activation response. Oncogene 1999 ; 18 : 1–8. [CrossRef] [PubMed] [Google Scholar]
  5. Limaye N, Wouters V, Uebelhoer M, et al. Somatic mutations in angiopoietin receptor gene TEK cause solitary and multiple sporadic venous malformations. Nat Genet 2009 ; 41 : 118–124. [CrossRef] [PubMed] [Google Scholar]
  6. Uebelhoer M, Nätynki M, Kangas J, et al. Venous malformation-causative TIE2 mutations mediate an AKT-dependent decrease in PDGFB. Hum Mol Genet 2013 ; 22 : 3438–3448. [CrossRef] [PubMed] [Google Scholar]
  7. Boscolo E, Limaye N, Huang L, et al. Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects. J Clin Invest 2015 ; 125 : 3491–3504. [CrossRef] [PubMed] [Google Scholar]
  8. Limaye N, Kangas J, Mendola A, et al. Somatic activating PIK3CA mutations cause venous malformation. Am J Hum Genet 2015 ; 97 : 914–921. [CrossRef] [PubMed] [Google Scholar]
  9. Julien LA, Roux PP. mTOR, la cible fonctionnelle de la rapamycine. Med Sci (Paris) 2010 ; 26 : 1056–1060. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  10. Sarbassov D, Ali SM, Sengupta S, et al. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol Cell 2006 ; 22 : 159–168. [CrossRef] [PubMed] [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.