Free Access
Issue
Med Sci (Paris)
Volume 28, Number 2, Février 2012
Page(s) 207 - 212
Section Repères
DOI https://doi.org/10.1051/medsci/2012282020
Published online 27 February 2012
  1. Sams-Dodd F. Research and market strategy: how choice of drug discovery approach can affect market position. Drug Discov Today 2007 ; 12 : 314–318. [CrossRef] [PubMed] [Google Scholar]
  2. Sams-Dodd F. Drug discovery: selecting the optimal approach. Drug Discov Today 2006 ; 11 : 465–472. [CrossRef] [PubMed] [Google Scholar]
  3. Sams-Dodd F. Target-based drug discovery: is something wrong? Drug Discov Today 2005 ; 10 : 139–147. [CrossRef] [PubMed] [Google Scholar]
  4. Xie L, Li J, Xie L, et al. Drug Discovery using chemical systems biology: identification of the protein-ligand binding network to explain the side effects of CETP inhibitors. PLoS Comp Biol 2009 ; 5 : e1000387. [CrossRef] [Google Scholar]
  5. Zak DE, Aderem A. Systems biology of innate immunity. Immunol Rev 2009 ; 227 : 264–282. [CrossRef] [PubMed] [Google Scholar]
  6. Kell D. Systems biology, metabolic modelling and metabolomics in drug discovery and development. Drug Discov Today 2006 ; 11 : 1085–1092. [CrossRef] [PubMed] [Google Scholar]
  7. Butcher EC, Berg EL, Kunkel EJ. Systems biology in drug discovery. Nat Biotech 2004 ; 22 : 1253–1259. [CrossRef] [Google Scholar]
  8. Dietrich JA, Yoshikuni Y, Fisher KJ, et al. A novel semi-biosynthetic route for artemisinin production using engineered substrate-promiscuous P450(BM3). ACS Chem Biol 2009 ; 4 : 261–267. [CrossRef] [PubMed] [Google Scholar]
  9. Anthony JR, Anthony LC, Nowroozi F, et al. Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4, 11-diene. Metab Eng 2009 ; 11 : 13–19. [CrossRef] [PubMed] [Google Scholar]
  10. Keasling JD. Synthetic biology for synthetic chemistry. ACS Chem Biol 2008 ; 3 : 64–76. [CrossRef] [PubMed] [Google Scholar]
  11. Szczebara FM, Chandelier C, Villeret C, et al. Total biosynthesis of hydrocortisone from a simple carbon source in yeast. Nat Biotech 2003 ; 21 : 143–149. [CrossRef] [PubMed] [Google Scholar]
  12. Kemmer C, Fluri DA, Witschi U, et al. A designer network coordinating bovine artificial insemination by ovulation-triggered release of implanted sperms. J Control Release 2011 ; 150 : 23–29. [CrossRef] [PubMed] [Google Scholar]
  13. Aubel D, Fussenegger M. Mammalian synthetic biology: from tools to therapies. Bioessays 2010 ; 32 : 332–345. [CrossRef] [PubMed] [Google Scholar]
  14. Gibson DG, Glass JI, Lartigue C, et al. Creation of a bacterial cell controlled by a chemically synthesized genome. Science 2010 ; 329 : 52–56. [CrossRef] [PubMed] [Google Scholar]
  15. Segura V. Génétique et amélioration d’Artemisia annua L. pour une production durable d’antipaludiques à base d’artémisinine. Med Sci (Paris) 2010 ; 26 : 701–703. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  16. Dumas B, Spagnoli R. Synthèse totale de l’hydrocortisone dans la levure de boulanger. Med Sci (Paris) 2003 ; 19 : 1059–1061. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  17. Häfner S. Les iGEM 2009 : la biologie synth-éthique. Med Sci (Paris) 2010 ; 26 : 986–992. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]
  18. Danchin A. Saurons-nous construire une bactérie synthétique ? Med Sci (Paris) 2008 ; 24 : 533–540. [CrossRef] [EDP Sciences] [PubMed] [Google Scholar]

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