Free Access
Issue
Med Sci (Paris)
Volume 27, Number 8-9, Août–Septembre 2011
Page(s) 733 - 736
Section M/S Revues
DOI https://doi.org/10.1051/medsci/2011278015
Published online 31 August 2011
  1. Haass C, Selkoe DJ. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer’s amyloid beta-peptide. Nat Rev Mol Cell Biol 2007 ; 8 : 101-112. [CrossRef] [PubMed] [Google Scholar]
  2. Palop JJ, Mucke L. Amyloid-beta-induced neuronal dysfunction in Alzheimer’s disease: from synapses toward neural networks. Nat Neurosci 2010 ; 13 : 812-818. [CrossRef] [PubMed] [Google Scholar]
  3. Selkoe DJ. Alzheimer’s disease is a synaptic failure. Science 2002 ; 298 : 789-791. [CrossRef] [PubMed] [Google Scholar]
  4. Small DH, Mok SS, Bornstein JC. Alzheimer’s disease and Abeta toxicity: from top to bottom. Nat Rev Neurosci 2001 ; 2 : 595-598. [CrossRef] [PubMed] [Google Scholar]
  5. Knobloch M, Mansuy IM. Dendritic spine loss and synaptic alterations in Alzheimer’s disease. Mol Neurobiol 2008 ; 37 : 73-82. [CrossRef] [PubMed] [Google Scholar]
  6. De Strooper B, Annaert W. Proteolytic processing and cell biological functions of the amyloid precursor protein. J Cell Sci 2000 ; 113 : 1857-1870. [PubMed] [Google Scholar]
  7. McGowan E, Pickford F, Kim J, et al. Abeta42 is essential for parenchymal and vascular amyloid deposition in mice. Neuron 2005 ; 47 : 191-199. [CrossRef] [PubMed] [Google Scholar]
  8. Marcello E, Epis R, Di Luca M. Amyloid flirting with synaptic failure: towards a comprehensive view of Alzheimer’s disease pathogenesis. Eur J Pharmacol 2008 ; 585 : 109-118. [CrossRef] [PubMed] [Google Scholar]
  9. Zheng H, Koo EH. The amyloid precursor protein: beyond amyloid. Mol Neurodegener 2006 ; 1 : 5. [CrossRef] [PubMed] [Google Scholar]
  10. Thinakaran G, Koo EH. Amyloid precursor protein trafficking, processing, and function. J Biol Chem 2008 ; 283 : 29615-29619. [CrossRef] [PubMed] [Google Scholar]
  11. Ghosal K, Vogt DL, Liang M, et al. Alzheimer’s disease-like pathological features in transgenic mice expressing the APP intracellular domain. Proc Natl Acad Sci USA 2009 ; 106 : 18367-18372. [CrossRef] [Google Scholar]
  12. Walsh DM, Klyubin I, Fadeeva JV, et al. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 2002 ; 416 : 535-539. [CrossRef] [PubMed] [Google Scholar]
  13. Ashe KH, Zahs KR. Probing the biology of Alzheimer’s disease in mice. Neuron 2010 ; 66 : 631-645. [CrossRef] [PubMed] [Google Scholar]
  14. Hsiao K, Chapman P, Nilsen S, et al. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 1996 ; 274 : 99-102. [CrossRef] [PubMed] [Google Scholar]
  15. Lesné S, Koh MT, Kotilinek L, et al. A specific amyloid-beta protein assembly in the brain impairs memory. Nature 2006 ; 440 : 352-357. [CrossRef] [PubMed] [Google Scholar]
  16. Balducci C, Beeg M, Stravalaci M, et al. Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein. Proc Natl Acad Sci USA 2010 ; 107 : 2295-2300. [CrossRef] [Google Scholar]
  17. Shankar GM, Li S, Mehta TH, et al. Amyloid-beta protein dimers isolated directly from Alzheimer’s brains impair synaptic plasticity and memory. Nat Med 2008 ; 14 : 837-842. [CrossRef] [PubMed] [Google Scholar]
  18. Walsh DM, Selkoe DJ. Deciphering the molecular basis of memory failure in Alzheimer’s disease. Neuron 2004 ; 44 : 181-193. [CrossRef] [PubMed] [Google Scholar]
  19. Lemere CA, Masliah E. Can Alzheimer disease be prevented by amyloid-beta immunotherapy?. Nat Rev Neurol 2010 ; 6 : 108-119. [CrossRef] [PubMed] [Google Scholar]
  20. Chapman PF, White GL, Jones MW, et al. Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice. Nat Neurosci 1999 ; 2 : 271-276. [CrossRef] [PubMed] [Google Scholar]
  21. Gureviciene I, Ikonen S, Gurevicius K, et al. Normal induction but accelerated decay of LTP in APP + PS1 transgenic mice. Neurobiol Dis 2004 ; 15 : 188-195. [CrossRef] [PubMed] [Google Scholar]
  22. Hsia AY, Masliah E, McConlogue L, et al. Plaque-independent disruption of neural circuits in Alzheimer’s disease mouse models. Proc Natl Acad Sci USA 1999 ; 96 : 3228-3233. [CrossRef] [Google Scholar]
  23. Palop JJ, Mucke L. Epilepsy and cognitive impairments in Alzheimer disease. Arch Neurol 2009 ; 66 : 435-440. [CrossRef] [PubMed] [Google Scholar]
  24. Chang EH, Savage MJ, Flood DG, et al. AMPA receptor downscaling at the onset of Alzheimer’s disease pathology in double knockin mice. Proc Natl Acad Sci USA 2006 ; 103 : 3410-3415. [CrossRef] [Google Scholar]
  25. Hsieh H, Boehm J, Sato C, et al. AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss. Neuron 2006 ; 52 : 831-843. [CrossRef] [PubMed] [Google Scholar]
  26. Snyder EM, Nong Y, Almeida CG, et al. Regulation of NMDA receptor trafficking by amyloid-beta. Nat Neurosci 2005 ; 8 : 1051-1058. [CrossRef] [PubMed] [Google Scholar]
  27. Li S, Hong S, Shepardson NE, et al. Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake. Neuron 2009 ; 62 : 788-801. [CrossRef] [PubMed] [Google Scholar]
  28. Lacor PN, Buniel MC, Furlow PW, et al. Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer’s disease. J Neurosci 2007 ; 27 : 796-807. [CrossRef] [PubMed] [Google Scholar]
  29. Wang HY, Lee DH, D’Andrea MR, et al. Beta-Amyloid(1–42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer’s disease pathology. J Biol Chem 2000; 275 : 5626-32. [CrossRef] [PubMed] [Google Scholar]
  30. Gasparini L, Dityatev A. Beta-amyloid and glutamate receptors. Exp Neurol 2008 ; 212 : 1-4. [CrossRef] [PubMed] [Google Scholar]
  31. Renner M, Lacor PN, Velasco PT, et al. Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5. Neuron 2010 ; 66 : 739-754. [CrossRef] [PubMed] [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.