Free Access
| Issue |
Med Sci (Paris)
Volume 26, Number 5, Mai 2010
|
|
|---|---|---|
| Page(s) | 459 - 460 | |
| Section | Nouvelles | |
| DOI | https://doi.org/10.1051/medsci/2010265459 | |
| Published online | 15 May 2010 | |
- Montagut C, Settleman J. Targeting the RAF-MEK-ERK pathway in cancer therapy. Cancer Lett 2009; 283 : 125–34. [Google Scholar]
- Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature 2002; 417 : 949–54. [Google Scholar]
- Ashton-Beaucage D, Therrien M. La signalisation RTK/RAS/ERK élargie : contributions de la génétique à l’assemblage d’un réseau de signalisation. Med Sci (Paris) 2010; 26 (sous presse). [Google Scholar]
- Claperon A, Therrien M. KSR and CNK: two scaffolds regulating RAS-mediated RAF activation. Oncogene 2007; 26 : 3143–58. [Google Scholar]
- Roy F, Laberge G, Douziech M, et al. KSR is a scaffold required for activation of the ERK/MAPK module. Genes Dev 2002; 16 : 427–38. [Google Scholar]
- Rajakulendran T, Sahmi M, Lefrancois M, et al. A dimerization-dependent mechanism drives RAF catalytic activation. Nature 2009; 461 : 542–5. [Google Scholar]
- Wan PT, Garnett MJ, Roe SM, et al. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell 2004; 116 : 855–67. [Google Scholar]
- Fenton AW. Allostery: an illustrated definition for the second secret of life. Trends Biochem Sci 2008; 33 : 420–5. [Google Scholar]
- Dar AC, Dever TE, Sicheri F. Higher-order substrate recognition of eIF2alpha by the RNA-dependent protein kinase PKR. Cell 2005; 122 : 887–900. [Google Scholar]
- Zhang X, Gureasko J, Shen K, et al. An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor. Cell 2006; 125 : 1137–49. [Google Scholar]
- Zeqiraj E, Filippi BM, Deak M, et al. Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation. Science 2009; 326 : 1707–11. [Google Scholar]
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.