Free Access
Issue |
Med Sci (Paris)
Volume 25, Number 12, Décembre 2009
Anticorps monoclonaux en thérapeutique
|
|
---|---|---|
Page(s) | 1149 - 1154 | |
Section | III - Un futur en développement | |
DOI | https://doi.org/10.1051/medsci/200925121149 | |
Published online | 15 December 2009 |
- Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 1975; 256 : 495–7. [Google Scholar]
- Bruggemann M, Caskey HM, Teale C, et al. A repertoire of monoclonal antibodies with human heavy chains from transgenic mice. Proc Natl Acad Sci USA 1989; 86 : 6709–13. [Google Scholar]
- Lonberg N, Taylor LD, Harding FA, et al. Antigen-specific human antibodies from mice comprising four distinct genetic modifications. Nature 1994; 368 : 856–9. [Google Scholar]
- Green LL, Hardy MC, Maynard-Currie CE, et al. Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YAC. Nat Genet 1994; 7 : 13–21. [Google Scholar]
- Taylor LD, Carmack CE, Huszar D, et al. Human immunoglobulin transgenes undergo rearrangement, somatic mutation and class switching in mice that lack endogenous IgM. Int Immunol 1994; 6 : 579–91. [Google Scholar]
- Adderson EE, Shackelford PG, Insel RA, et al. Immunoglobulin light chain variable region gene sequences for human antibodies to Haemophilus influenzae type b capsular polysaccharide are dominated by a limited number of V kappa and V lambda segments and VJ combinations. J Clin Invest 1992; 89 : 729–38. [Google Scholar]
- Mendez MJ, Green LL, Corvalan JR, et al. Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice. Nat Genet 1997; 15 : 146–56. [Google Scholar]
- Green LL, Jakobovits A. Regulation of B cell development by variable gene complexity in mice reconstituted with human immunoglobulin yeast artificial chromosomes. J Exp Med 1998; 188 : 483–95. [Google Scholar]
- Tomizuka K, Shinohara T, Yoshida H, et al. Double trans-chromosomic mice : maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies. Proc Natl Acad Sci USA 2000; 97 : 722–7. [Google Scholar]
- Kuroiwa Y, Tomizuka K, Shinohara T, et al. Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts. Nat Biotechnol 2000; 18 : 1086–90. [Google Scholar]
- Popov AV, Zou X, Xian J, Nicholson IC, Bruggemann M. A human immunoglobulin lambda locus is similarly well expressed in mice and humans. J Exp Med 1999; 189 : 1611–20. [Google Scholar]
- Nicholson IC, Zou X, Popov AV, et al. Antibody repertoires of four- and five-feature translocus mice carrying human immunoglobulin heavy chain and kappa and lambda light chain yeast artificial chromosomes. J Immunol 1999; 163 : 6898–906. [Google Scholar]
- Zou YR, Muller W, Gu H, Rajewsky K. Cre-loxP-mediated gene replacement : a mouse strain producing humanized antibodies. Curr Biol 1994; 4 : 1099–103. [Google Scholar]
- Harding FA, Lonberg N. Class switching in human immunoglobulin transgenic mice. Ann NY Acad Sci 1995; 764 : 536–46. [Google Scholar]
- Ball WJ, Jr., Kasturi R, Dey P, et al. Isolation and characterization of human monoclonal antibodies to digoxin. J Immunol 1999; 163 : 2291–8. [Google Scholar]
- Mukherjee J, Chios K, Fishwild D, et al. Human Stx2-specific monoclonal antibodies prevent systemic complications of Escherichia coli O157 : H7 infection. Infect Immun 2002; 70 : 612–9. [Google Scholar]
- He Y, Honnen WJ, Krachmarov CP, et al. Efficient isolation of novel human monoclonal antibodies with neutralizing activity against HIV-1 from transgenic mice expressing human Ig loci. J Immunol 2002; 169 : 595–605. [Google Scholar]
- Chang Q, Zhong Z, Lees A, et al. Structure-function relationships for human antibodies to pneumococcal capsular polysaccharide from transgenic mice with human immunoglobulin Loci. Infect Immun 2002; 70 : 4977–86. [Google Scholar]
- Villadsen LS, Schuurman J, Beurskens F, et al. Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model. J Clin Invest 2003; 112 : 1571–80. [Google Scholar]
- Bekker PJ, Holloway DL, Rasmussen AS, et al. A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women. J Bone Miner Res 2004; 19 : 1059–66. [Google Scholar]
- Yang XD, Corvalan JR, Wang P, et al. Fully human anti-interleukin-8 monoclonal antibodies : potential therapeutics for the treatment of inflammatory disease states. J Leukoc Biol 1999; 66 : 401–10. [Google Scholar]
- Teeling JL, French RR, Cragg MS, et al. Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas. Blood 2004; 104 : 1793–800. [Google Scholar]
- Schuler W, Bigaud M, Brinkmann V, et al. Efficacy and safety of ABI793, a novel human anti-human CD154 monoclonal antibody, in cynomolgus monkey renal allotransplantation. Transplantation 2004; 77 : 717–26. [Google Scholar]
- Bleeker WK, Lammerts van Bueren JJ, van Ojik HH, et al. Dual mode of action of a human anti-epidermal growth factor receptor monoclonal antibody for cancer therapy. J Immunol 2004; 173 : 4699–707. [Google Scholar]
- Imakiire T, Kuroki M, Shibaguchi H, et al. Generation, immunologic characterization and antitumor effects of human monoclonal antibodies for carcinoembryonic antigen. Int J Cancer 2004; 108 : 564–70. [Google Scholar]
- Foon KA, Yang XD, Weiner LM, et al. Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody. Int J Radiat Oncol Biol Phys 2004; 58 : 984–90. [Google Scholar]
- Skov L, Kragballe K, Zachariae C, et al. HuMax-CD4 : a fully human monoclonal anti-CD4 antibody for the treatment of psoriasis vulgaris. Arch Dermatol 2003; 139 : 1433–9. [Google Scholar]
- Keler T, Halk E, Vitale L, et al. Activity and safety of CTLA-4 blockade combined with vaccines in cynomolgus macaques. J Immunol 2003; 171 : 6251–9. [Google Scholar]
- Phan GQ, Yang JC, Sherry RM, et al. Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci USA 2003; 100 : 8372–7. [Google Scholar]
- Hermeling S, Crommelin DJ, Schellekens H, Jiskoot W. Structure-immunogenicity relationships of therapeutic proteins. Pharm Res 2004; 21 : 897–903. [Google Scholar]
- Mannon PJ, Fuss IJ, Mayer L, et al. Anti-interleukin-12 antibody for active Crohn’s disease. N Engl J Med 2004; 351 : 2069–79. [Google Scholar]
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.