Issue
Med Sci (Paris)
Volume 25, Number 10, Octobre 2009
Accidents vasculaires cérébraux
Page(s) 855 - 857
Section M/S revues : Accidents vasculaires cérébraux (2)
DOI https://doi.org/10.1051/medsci/20092510855
Published online 15 October 2009
  1. Polavarapu R, An J, Zhang C, Yepes M. Regulated intramembrane proteolysis of the low-density lipoprotein receptor-related protein mediates ischemic cell death. Am J Pathol 2008; 172 : 1355–62. [Google Scholar]
  2. Angles-Cano E, Balaton A, Le Bonniec B, et al. Production of monoclonal antibodies to the high fibrin-affinity, tissue-type plasminogen activator of human plasma. Demonstration of its endothelial origin by immunolocalization. Blood 1985; 66 : 913–20. [Google Scholar]
  3. Gualandris A, Jones TE, Strickland S, Tsirka SE. Membrane depolarization induces calcium-dependent secretion of tissue plasminogen activator. J Neurosci 1996; 16 : 2220–5. [Google Scholar]
  4. Wang YF, Tsirka SE, Strickland S, et al. Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice. Nat Med 1998; 4 : 228–31. [Google Scholar]
  5. Nicole O, Docagne F, Ali C, et al. The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling. Nat Med 2001; 7 : 59–64. [Google Scholar]
  6. Nagai N, De Mol M, Lijnen HR, et al. Role of plasminogen system components in focal cerebral ischemic infarction : a gene targeting and gene transfer study in mice. Circulation 1999; 99 : 2440–4. [Google Scholar]
  7. Tsirka SE, Rogove AD, Bugge TH, et al. An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus. J Neurosci 1997; 17 : 543–52. [Google Scholar]
  8. Chen ZL, Strickland S. Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin. Cell 1997; 91 : 917–25. [Google Scholar]
  9. Fernandez-Monreal M, Lopez-Atalaya JP, Benchenane K, et al. Is tissue-type plasminogen activator a neuromodulator ? Mol Cell Neurosci 2004; 25 : 594–601. [Google Scholar]
  10. Armstead WM, Nassar T, Akkawi S, et al. Neutralizing the neurotoxic effects of exogenous and endogenous tPA. Nat Neurosci 2006; 9 : 1150–5. [Google Scholar]
  11. Benchenane K, Castel H, Boulouard M, et al. Anti-NR1 N-terminal-domain vaccination unmasks the crucial action of tPA on NMDA-receptor-mediated toxicity and spatial memory. J Cell Sci 2007; 120 : 578–85. [Google Scholar]
  12. Lopez-Atalaya JP, Roussel BD, Ali C, et al. Recombinant Desmodus rotundus salivary plasminogen activator crosses the blood-brain barrier through a low-density lipoprotein receptor-related protein-dependent mechanism without exerting neurotoxic effects. Stroke 2007; 38 : 1036–43. [Google Scholar]
  13. Su EJ, Fredriksson L, Geyer M, et al. Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke. Nat Med 2008; 14 : 731–7. [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.