Free Access
Med Sci (Paris)
Volume 24, Number 11, Novembre 2008
Page(s) 901 - 903
Section Nouvelles
Published online 15 November 2008
  1. Chowdhury D, Lieberman J. Death by a thousand cuts: granzyme pathways of programmed cell death. Annu Rev Immunol 2008; 26 : 389–420. [Google Scholar]
  2. Lieberman J, Fan Z. Nuclear war: the granzyme A-bomb. Curr Opin Immunol 2003; 15 : 553–9. [Google Scholar]
  3. Beresford PJ, Zhang D, Oh DY, et al. Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks. J Biol Chem 2001; 276 : 43285–93. [Google Scholar]
  4. Fan Z, Beresford PJ, Oh DY, et al. Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor. Cell 2003; 112 : 659–72. [Google Scholar]
  5. Chowdhury D, Beresford PJ, Zhu P, et al. The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death. Mol Cell 2006; 23 : 133–42. [Google Scholar]
  6. Fan Z, Beresford PJ, Zhang D, et al. HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A. Mol Cell Biol 2002; 22 : 2810–20. [Google Scholar]
  7. Fan Z, Beresford PJ, Zhang D, et al. Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A. Nat Immunol 2003; 4 : 145–53. [Google Scholar]
  8. Zhu P, Zhang D, Chowdhury D, et al. Granzyme A, which causes single-stranded DNA damage, targets the double-strand break repair protein Ku70. EMBO Rep 2006; 7 : 431–7. [Google Scholar]
  9. Martinvalet D, Zhu P, Lieberman J. Granzyme A induces caspase-independent mitochondrial damage, a required first step for apoptosis. Immunity 2005; 22 : 355–70. [Google Scholar]
  10. Martinvalet D, Dykxhoorn DM, Ferrini R, et al. Granzyme A cleaves a mitochondrial complex I protein to initiate caspase-independent cell death. Cell 2008; 133 : 681–92. [Google Scholar]
  11. Liu Z, Jang SW, Liu X, et al. Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase. Mol Cell 2008; 29 : 665–78. [Google Scholar]
  12. Ménasché G, Ménager M, Le Deist F, Fischer A, de Saint Basile G. Défaut d’exocytose des granules lytiques : plusieurs causes, un même effet. Med Sci (Paris) 2006; 22 : 733–8. [Google Scholar]
  13. Barouki R. Stress oxydant et vieillissement. Med Sci (Paris) 2006; 22 : 266–72. [Google Scholar]

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