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Home All issues Volume 24 / No 10 (Octobre 2008) Med Sci (Paris), 24 10 (2008) 833-840 References
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Issue
Med Sci (Paris)
Volume 24, Number 10, Octobre 2008
Page(s) 833 - 840
Section M/S revues
DOI https://doi.org/10.1051/medsci/20082410833
Published online 15 October 2008
  1. Broers JL, Ramaekers FC, Bonne G, et al. Nuclear lamins : laminopathies and their role in premature ageing. Physiol Rev 2006; 86 : 967–1008. [Google Scholar]
  2. Schmidt WK, Tam A, Fujimura-Kamada K, et al. Endoplasmic reticulum membrane localization of Rce1p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavage. Proc Natl Acad Sci USA 1998; 95 : 11175–80. [Google Scholar]
  3. Choy E, Chiu VK, Silletti J, et al. Endomembrane trafficking of ras : the CAAX motif targets proteins to the ER and Golgi. Cell 1999; 98 : 69–80. [Google Scholar]
  4. Firmbach-Kraft I, Stick R. Analysis of nuclear lamin isoprenylation in Xenopus oocytes : isoprenylation of lamin B3 precedes its uptake into the nucleus. J Cell Biol 1995; 129 : 17–24. [Google Scholar]
  5. Bonne G, Di Barletta MR, Varnous S, et al. Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy. Nat Genet 1999; 21 : 285–8. [Google Scholar]
  6. Zinn-Justin S. Maladies génétiques et lamines de type A : apport de la biologie structurale. Med Sci (Paris) 2002; 18 : 1054–5. [Google Scholar]
  7. Lammerding, J. Schulze PC, Takahashi T, et al. Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction. J Clin Invest 2004; 113 : 349–51. [Google Scholar]
  8. Lloyd DJ, Trembath RC, Shackleton S. A novel interaction between lamin A and SREBP1 : implications for partial lipodystrophy and other laminopathies. Hum Mol Genet 2002; 117 : 769–77. [Google Scholar]
  9. Navarro CL, Cau P, Levy N. Molecular bases of progeroid syndromes. Hum Mol Genet 2006; 15 : R151–61. [Google Scholar]
  10. Markiewicz E, Dechat T, Foisner R, et al. Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma protein. Mol Biol Cell 2002; 1312 : 4401–13. [Google Scholar]
  11. Novelli, G, Muchir, A, Sangiuolo F, et al. Mandibuloacral dysplasia is caused by a mutation in LMNA-encoding lamin A/C. Am J Hum Genet 2002; 71 : 426–31. [Google Scholar]
  12. De Sandre-Giovannoli A, Bernard R, Cau P, et al. Lamin a truncation in Hutchinson-Gilford progeria. Science 2003; 300 : 2055. [Google Scholar]
  13. Navarro CL, Cadinanos J, De Sandre-Giovannoli A, et al. Loss of ZMPSTE24 (FACE-1) causes autosomal recessive restrictive dermopathy and accumulation of Lamin A precursors. Hum Mol Genet 2005; 1411 : 1503–13. [Google Scholar]
  14. Navarro CL, De Sandre-Giovannoli A, Bernard R, et al. Lamin A and ZMPSTE24 (FACE-1) defects cause nuclear disorganization and identify restrictive dermopathy as a lethal neonatal laminopathy. Hum Mol Genet 2004; 1320 : 2493–503. [Google Scholar]
  15. Agarwal AK, Fryns JP, Auchus RJ, et al. Zinc metalloproteinase, ZMPSTE24, is mutated in mandibuloacral dysplasia. Hum Mol Genet 2003; 1216 : 1995–2001. [Google Scholar]
  16. Goldman RD, Shumaker DK, Erdos MR, et al. Accumulation of mutant Lamin causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci USA 2004; 101 : 8963–8. [Google Scholar]
  17. Sullivan T, Escalante-Alcalde D, Bhatt H, et al. Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy. J Cell Biol 1999; 1475 : 913–20. [Google Scholar]
  18. Bergo MO, Gavino B, Ross J, et al. Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect. Proc Natl Acad Sci USA 2002; 99 : 13049–54. [Google Scholar]
  19. Pendas AM, Zhou Z, Cadinanos J, et al. Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice. Nat Genet 2002; 311 : 94–9. [Google Scholar]
  20. Liu B, Wang J, Chan KM, et al. Genomic instability in laminopathy-based premature aging. Nat Med 2005; 117 : 780–5. [Google Scholar]
  21. Varela I, Cadinanos J, Pendas AM, et al. Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation. Nature 2005; 437 : 564–8. [Google Scholar]
  22. Fong LG, Ng JK, Lammerding J, et al. Prelamin A and lamin A appear to be dispensable in the nuclear lamina. J Clin Invest 2006; 116 : 743–52. [Google Scholar]
  23. Fong LG, Ng JK, Meta M, et al. Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice. Proc Natl Acad Sci USA 2004; 101 : 18111–6. [Google Scholar]
  24. Scaffidi P, Misteli T. Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome. Nat Med 2005; 11 : 440–5. [Google Scholar]
  25. Fong LG, Frost D, Meta M, et al. A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria. Science 2006; 311 : 1621–3. [Google Scholar]
  26. Pan J, She M, Xu ZX, et al. Farnesyltransferase inhibitors induce DNA damage via reactive oxygen species in human cancer cells. Cancer Res 2005; 65 : 3671–81. [Google Scholar]
  27. Van Beek E, Pieterman E, Cohen L, et al. Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates. Biochem Biophys Res Commun 1999; 264 : 108–11. [Google Scholar]
  28. Coffinier C, Hudon SE, Farber EA, et al. HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells. Proc Natl Acad Sci USA 2007; 104 : 13432–7. [Google Scholar]
  29. Caron M, Auclair M, Donadille B, et al. Human lipodystrophies linked to mutations in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative stress and premature cellular senescence. Cell Death Differ 2007; 14 : 1759–67. [Google Scholar]
  30. Scaffidi P, Misteli T. Lamin A-dependent nuclear defects in human aging. Science 2006; 312 : 1059–63. [Google Scholar]
  31. Mazières J, Pradines A, Favre G. Les inhibiteurs de farnésyl transférase : une cible peut en cacher une autre. Med Sci (Paris) 2003; 19 : 211–6. [Google Scholar]
  32. Langui D, Lachapelle F, Duyckaerts C. Modèles animaux des maladies neuro-dégénératives. Med Sci (Paris) 2007; 23 : 180–6. [Google Scholar]
  33. Varela I, Pereira S, Ugalde AP, et al. Combined treatment with statins and aminobisphosphonatos extends longevity in a mouse model of human premature aging. Nat Med 2008; 14 : 767–72. [Google Scholar]
  34. Gilgenkrantz H. Une nouvelle piste thérapeutique dans le traitement des syndromes progéroïdes. Med Sci (Paris) 2008; 24 : 819. [Google Scholar]

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