Free Access
Med Sci (Paris)
Volume 23, Number 12, Décembre 2007
Page(s) 1115 - 1124
Section M/S revues
Published online 15 December 2007
  1. Steeg PS, Bevilacqua G, Kopper L, et al. Evidence for a novel gene associated with low tumor metastatic potential. J Natl Cancer Inst 1988; 80 : 200–4. [Google Scholar]
  2. Steeg PS. Metastasis suppressors alter the signal transduction of cancer cells. Nat Rev Cancer 2003; 3 : 55–63. [Google Scholar]
  3. Christofori G. New signals from the invasive front. Nature 2006; 441 : 444–50. [Google Scholar]
  4. Nguyen DX, Massague J. Genetic determinants of cancer metastasis. Nat Rev Genet 2007; 8 : 341–52. [Google Scholar]
  5. Rinker-Schaeffer CW, O’Keefe JP, Welch DR, Theodorescu D. Metastasis suppressor proteins: discovery, molecular mechanisms, and clinical application. Clin Cancer Res 2006; 12 : 3882–9. [Google Scholar]
  6. Wallet V, Mutzel R, Troll H, et al. Dictyostelium nucleoside diphosphate kinase highly homologous to Nm23 and Awd proteins involved in mammalian tumor metastasis and Drosophila development. J Natl Cancer Inst 1990; 82 : 1199–202. [Google Scholar]
  7. Lacombe ML, Milon L, Munier A, et al. The human Nm23/nucleoside diphosphate kinases. J Bioenerg Biomembr 2000; 32 : 247–58. [Google Scholar]
  8. Boissan M, Lacombe ML. Nm23/NDP kinases in hepatocellular carcinoma. J Bioenerg Biomembr 2006; 38 : 169–75. [Google Scholar]
  9. Boissan M, Wendum D, Arnaud-Dabernat S, et al. Increased lung metastasis in transgenic NM23-Null/SV40 mice with hepatocellular carcinoma. J Natl Cancer Inst 2005; 97 : 836–45. [Google Scholar]
  10. Otsuki Y, Tanaka M, Yoshii S, et al. Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1. Proc Natl Acad Sci USA 2001; 98 : 4385–90. [Google Scholar]
  11. Salerno M, Palmieri D, Bouadis A, et al. Nm23-H1 metastasis suppressor expression level influences the binding properties, stability, and function of the kinase suppressor of Ras1 (KSR1) Erk scaffold in breast carcinoma cells. Mol Cell Biol 2005; 25 : 1379–88. [Google Scholar]
  12. Dammai V, Adryan B, Lavenburg KR, Hsu T. Drosophila awd, the homolog of human nm23, regulates FGF receptor levels and functions synergistically with shi/dynamin during tracheal development. Genes Dev 2003; 17 : 2812–24. [Google Scholar]
  13. Fournier HN, Dupe-Manet S, Bouvard D, et al. Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement. J Biol Chem 2002; 277 : 20895–902. [Google Scholar]
  14. Horak CE, Lee JH, Elkahloun A, et al. NM23-H1 suppresses tumor cell motility by downregulating the LPA receptor. Cancer Res 2007; 67 : 7238–46. [Google Scholar]
  15. Goswami S, Yoon J, Abramczyk B, et al. Molecular and functional interactions between Escherichia coli nucleoside-diphosphate kinase and the uracil-DNA glycosylase Ung. J Biol Chem 2006; 281 : 32131–9. [Google Scholar]
  16. Fan Z, Beresford PJ, Oh DY, et al. Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor. Cell 2003; 112 : 659–72. [Google Scholar]
  17. Gildea JJ, Seraj MJ, Oxford G, et al. RhoGDI2 is an invasion and metastasis suppressor gene in human cancer. Cancer Res 2002; 62 : 6418–23. [Google Scholar]
  18. Gelman IH, Gao L. SSeCKS/Gravin/AKAP12 metastasis suppressor inhibits podosome formation via RhoA- and Cdc42-dependent pathways. Mol Cancer Res 2006; 4 : 151–8. [Google Scholar]
  19. Su B, Zheng Q, Vaughan MM, et al. SSeCKS metastasis-suppressing activity in MatLyLu prostate cancer cells correlates with vascular endothelial growth factor inhibition. Cancer Res 2006; 66 : 5599–607. [Google Scholar]
  20. Nash KT, Phadke PA, Navenot JM, et al. Requirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancy. J Natl Cancer Inst 2007; 99 : 309–21. [Google Scholar]
  21. Yan C, Wang H, Boyd DD. KiSS-1 represses 92-kDa type IV collagenase expression by down-regulating NF-kappa B binding to the promoter as a consequence of Ikappa Balpha -induced block of p65/p50 nuclear translocation. J Biol Chem 2001; 276 : 1164–72. [Google Scholar]
  22. Goldberg SF, Miele ME, Hatta N, et al. Melanoma metastasis suppression by chromosome 6: evidence for a pathway regulated by CRSP3 and TXNIP. Cancer Res 2003; 63 : 432–40. [Google Scholar]
  23. Aguirre-Ghiso JA, Estrada Y, Liu D, Ossowski L. ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK). Cancer Res 2003; 63 : 1684–95. [Google Scholar]
  24. Vander Griend DJ, Kocherginsky M, Hickson JA, et al. Suppression of metastatic colonization by the context-dependent activation of the c-Jun NH2-terminal kinase kinases JNKK1/MKK4 and MKK7. Cancer Res 2005; 65 : 10984–91. [Google Scholar]
  25. Hickson JA, Huo D, Vander Griend DJ, et al. The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma. Cancer Res 2006; 66 : 2264–70. [Google Scholar]
  26. Motwani M, Sirotnak FM, She Y, et al. Drg1, a novel target for modulating sensitivity to CPT-11 in colon cancer cells. Cancer Res 2002; 62 : 3950–5. [Google Scholar]
  27. Schuierer MM, Bataille F, Weiss TS, et al. Raf kinase inhibitor protein is downregulated in hepatocellular carcinoma. Oncol Rep 2006; 16 : 451–6. [Google Scholar]
  28. Odintsova E, Sugiura T, Berditchevski F. Attenuation of EGF receptor signaling by a metastasis suppressor, the tetraspanin CD82/KAI-1. Curr Biol 2000; 10 : 1009–12. [Google Scholar]
  29. Sridhar SC, Miranti CK. Tetraspanin KAI1/CD82 suppresses invasion by inhibiting integrin-dependent crosstalk with c-Met receptor and Src kinases. Oncogene 2006; 25 : 2367–78. [Google Scholar]
  30. Bandyopadhyay S, Zhan R, Chaudhuri A, et al. Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression. Nat Med 2006; 12 : 933–8. [Google Scholar]
  31. Cicek M, Fukuyama R, Welch DR, et al. Breast cancer metastasis suppressor 1 inhibits gene expression by targeting nuclear factor-kappaB activity. Cancer Res 2005; 65 : 3586–95. [Google Scholar]
  32. Samant RS, Clark DW, Fillmore RA, et al. Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-kappaB activation. Mol Cancer 2007; 6 : 6. [Google Scholar]
  33. Saunders MM, Seraj MJ, Li Z, et al. Breast cancer metastatic potential correlates with a breakdown in homospecific and heterospecific gap junctional intercellular communication. Cancer Res 2001; 61 : 1765–7. [Google Scholar]
  34. Luo JL, Tan W, Ricono JM, et al. Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin. Nature 2007; 446 : 690–4. [Google Scholar]
  35. Hailat N, Keim DR, Melhem RF, et al. High levels of p19/nm23 protein in neuroblastoma are associated with advanced stage disease and with N-myc gene amplification. J Clin Invest 1991; 88 : 341–5. [Google Scholar]
  36. Cunningham SC, Gallmeier E, Hucl T, et al. Targeted deletion of MKK4 in cancer cells: a detrimental phenotype manifests as decreased experimental metastasis and suggests a counterweight to the evolution of tumor-suppressor loss. Cancer Res 2006; 66 : 5560–4. [Google Scholar]
  37. Sheth SS, Bodnar JS, Ghazalpour A, et al. Hepatocellular carcinoma in Txnip-deficient mice. Oncogene 2006; 25 : 3528–36. [Google Scholar]
  38. Palmieri D, Halverson DO, Ouatas T, et al. Medroxyprogesterone acetate elevation of Nm23-H1 metastasis suppressor expression in hormone receptor-negative breast cancer. J Natl Cancer Inst 2005; 97 : 632–42. [Google Scholar]
  39. Titus B, Frierson HF Jr, Conaway M, et al. Endothelin axis is a target of the lung metastasis suppressor gene RhoGDI2. Cancer Res 2005; 65 : 7320–7. [Google Scholar]
  40. Li J, Zhou J, Chen G, et al. Inhibition of ovarian cancer metastasis by adeno-associated virus-mediated gene transfer of nm23H1 in an orthotopic implantation model. Cancer Gene Ther 2006; 13 : 266–72. [Google Scholar]
  41. Takeda T, Hattori N, Tokuhara T, et al. Adenoviral transduction of MRP-1/CD9 and KAI1/CD82 inhibits lymph node metastasis in orthotopic lung cancer model. Cancer Res 2007; 67 : 1744–9. [Google Scholar]
  42. Chabas D. L’ostéopontine, une molécule aux multiples facettes. Med Sci (Paris) 2005; 21 : 832–8. [Google Scholar]
  43. Nasarre P, Constantin B, Drabkin HA, Roche J. Sémaphorines et cancer : état des lieux. Med Sci (Paris) 2005; 21 : 641–7. [Google Scholar]
  44. Desjardins SF, Berchiche YA, Haddad E, Heveker N. CXCR4, un récepteur de chimiokine aux multiples talents. Med Sci (Paris) 2007; 23 : 980–4. [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.