Free Access
Issue |
Med Sci (Paris)
Volume 22, Number 1, Janvier 2006
|
|
---|---|---|
Page(s) | 41 - 46 | |
Section | M/S revues | |
DOI | https://doi.org/10.1051/medsci/200622141 | |
Published online | 15 January 2006 |
- Bardoni B, Mandel JL Advances in understanding of fragile X pathogenesis and FMRP function, and in identification of X linked mental retardation genes. Curr Opin Genet Dev 2002; 12 : 284–93. [Google Scholar]
- O’Donnell WT, Warren ST. A decade of molecular studies of fragile X syndrome. Annu Rev Neurosci 2002; 25 : 315–38. [Google Scholar]
- Hagerman PJ, Cronister A. Fragile X syndrome : diagnosis, treatment and research. Baltimore : University Press, 1996. [Google Scholar]
- Khandjian EW. Biology of the fragile X mental retardation protein, an RNA-binding protein. Biochem Cell Biol 1999; 77 : 331–42. [Google Scholar]
- Mazroui R, Huot ME, Tremblay S, et al. Fragile X Mental Retardation protein determinants required for its association with polyribosomal mRNPs. Hum Mol Genet 2003; 12 : 3087–96. [Google Scholar]
- Devys D, Lutz Y, Rouyer N, et al. The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation. Nat Genet 1993; 4 : 335–40. [Google Scholar]
- Consortium TD-BFX. Fmr1 knockout mice : a model to study fragile X mental retardation. The Dutch-Belgian Fragile X Consortium. Cell 1994; 78 : 23–33. [Google Scholar]
- Khandjian EW, Bardoni B, Corbin F, et al. Novel isoforms of the fragile X related protein FXR1P are expressed during myogenesis. Hum Mol Genet 1998; 7 : 2121–8. [Google Scholar]
- Mientjes EJ, Willemsen R, Kirkpatrick LL, et al. Fxr1 knockout mice show a striated muscle phenotype : implications for Fxr1p function in vivo. Hum Mol Genet 2004; 13 : 1291–302. [Google Scholar]
- Huot ME, Bisson N, Davidovic L, et al. The RNA-binding protein Fragile X-related 1 regulates somite formation in Xenopus laevis. Mol Biol Cell 2005; 16 : 4350–61. [Google Scholar]
- Bontekoe CJ, McIlwain KL, Nieuwenhuizen IM, et al. Knockout mouse model for Fxr2 : a model for mental retardation. Hum Mol Genet 2002; 11 : 487–98. [Google Scholar]
- Guduric-Fuchs J, Mohrlen F, Frohme M, Frank U. A fragile X mental retardation-like gene in a cnidarian. Gene 2004; 343 : 231–8. [Google Scholar]
- Corbin F, Bouillon M, Fortin A, et al. The fragile X mental retardation protein is associated with poly(A)+ mRNA in actively translating polyribosomes. Hum Mol Genet 1997; 6 : 1465–72. [Google Scholar]
- Brown V, Jin P, Ceman S, et al. Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome. Cell 2001; 107 : 477–87. [Google Scholar]
- Mazroui R, Huot ME, Tremblay S, et al. Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression. Hum Mol Genet 2002; 11 : 3007–17. [Google Scholar]
- Jin P, Alisch RS, Warren ST. RNA and microRNAs in fragile X mental retardation. Nat Cell Biol 2004; 6 : 1048–53. [Google Scholar]
- Khandjian EW, Huot ME, Tremblay S, et al. Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles. Proc Natl Acad Sci USA 2004; 101 : 13357–62. [Google Scholar]
- Stefani G, Fraser CE, Darnell JC, Darnell RB. Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells. J Neurosci 2004; 24 : 7272–6. [Google Scholar]
- Darnell JC, Mostovetsky O, Darnell RB. FMRP RNA targets : identification and validation. Genes Brain Behav 2005; 4 : 341–9. [Google Scholar]
- Miyashiro KY, Beckel-Mitchener A, Purk TP, et al. RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice. Neuron 2003; 37 : 417–31. [Google Scholar]
- Antar LN, Afroz R, Dictenberg JB, et al. Metabotropic glutamate receptor activation regulates fragile X mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses. J Neurosci 2004; 24 : 2648–55. [Google Scholar]
- Davidovic L, Tremblay S, De Koninck P, Khandjian EW. Fragile X Mental Retardation Protein : To be or not to be a Translational Repressor. In : Sung YJ, Denman RB, eds. The molecular basis of fragile X syndrome. Kerala (India) : Research Signpost, 2005 : 129–43. [Google Scholar]
- Ivanyi-Nagy R, Davidovic L, Khandjian EW, Darlix JL. Disordered RNA chaperone proteins : from functions to disease. Cell Mol Life Sci 2005; 62 : 1–9. [Google Scholar]
- Khandjian EW, Corbin F, Woerly S, Rousseau F. The fragile X mental retardation protein is associated with ribosomes. Nat Genet 1996; 12 : 91–3. [Google Scholar]
- Weiler IJ, Irwin SA, Klintsova AY, et al. Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation. Proc Natl Acad Sci USA 1997; 94 : 5395–400. [Google Scholar]
- Greenough WT, Klintsova AY, Irwin SA, et al. Synaptic regulation of protein synthesis and the fragile X protein. Proc Natl Acad Sci USA 2001; 98 : 7101–6. [Google Scholar]
- Castets M, Schaeffer C, Bechara E, et al. FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts. Hum Mol Genet 2005; 14 : 835–44. [Google Scholar]
- Kedersha N, Anderson P. Stress granules : sites of mRNA triage that regulate mRNA stability and translatability. Biochem Soc Trans 2002; 30 : 963–9. [Google Scholar]
- Wickens M, Goldstrohm A. Molecular biology. A place to die, a place to sleep. Science 2003; 300 : 753–5. [Google Scholar]
- Vanderklish PW, Edelman GM. Differential translation and fragile X syndrome. Genes Brain Behav 2005; 4 : 360–84. [Google Scholar]
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