Free Access
Med Sci (Paris)
Volume 21, Number 1, Janvier 2005
Page(s) 43 - 48
Section M/S Revues
Published online 15 January 2005
  1. Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997; 88 : 323–31. [Google Scholar]
  2. Amor M, Parker KL, Globerman H, et al. Mutation in the CYP21B gene (Ile-172-Asn) causes steroid 21-hydroxylase deficiency. Proc Natl Acad Sci USA 1988; 85 : 1600–4. [Google Scholar]
  3. Purandare SM, Patel PI. Recombination hot spots and human disease. Genome Res 1997; 7 : 773–86. [Google Scholar]
  4. Wiesmuller L, Cammenga J, Deppert WW. In vivo assay of p53 function in homologous recombination between simian virus 40 chromosomes. J Virol 1996; 70 : 737–44. [Google Scholar]
  5. Bishop AJ, Hollander MC, Kosaras B, et al. Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development. Cancer Res 2003; 63 : 5335–43. [Google Scholar]
  6. Meyn MS, Strasfeld L, Allen C. Testing the role of p53 in the expression of genetic instability and apoptosis in ataxia-telangiectasia. Int J Radiat Biol 1994; 66 : S141–9. [Google Scholar]
  7. Bertrand P, Rouillard D, Boulet A, et al. Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein. Oncogene 1997; 14 : 1117–22. [Google Scholar]
  8. Mekeel KL, Tang W, Kachnic LA, et al. Inactivation of p53 results in high rates of homologous recombination. Oncogene 1997; 14 : 1847–57. [Google Scholar]
  9. Gebow D, Miselis N, Liber HL. Homologous and nonhomologous recombination resulting in deletion : effects of p53 status, microhomology, and repetitive DNA length and orientation. Mol Cell Biol 2000; 20 : 4028–35. [Google Scholar]
  10. Lu X, Lozano G, Donehower LA. Activities of wildtype and mutant p53 in suppression of homologous recombination as measured by a retroviral vector system. Mutat Res 2003; 522 : 69–83. [Google Scholar]
  11. Saintigny Y, Rouillard D, Chaput B, et al. Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint. Oncogene 1999; 18 : 3553–63. [Google Scholar]
  12. Lambert S, Lopez BS. Characterization of mammalian RAD51 double strand break repair using non lethal dominant negative forms. EMBO J 2000; 19 : 3090–9. [Google Scholar]
  13. Wang YY, Maher VM, Liskay RM, McCormick JJ. Carcinogens can induce homologous recombination between duplicated chromosomal sequences in mouse L cells. Mol Cell Biol 1988; 8 : 196–202. [Google Scholar]
  14. Akyuz N, Boehden GS, Susse S, et al. DNA substrate dependence of p53-mediated regulation of double-strand break repair. Mol Cell Biol 2002; 22 : 6306–17. [Google Scholar]
  15. Michel B, Flores MJ, Viguera E, et al. Rescue of arrested replication forks by homologous recombination. Proc Natl Acad Sci USA 2001; 98 : 8181–8. [Google Scholar]
  16. Saintigny Y, Delacote F, Vares G, et al. Characterization of homologous recombination induced by replication inhibition in mammalian cells. EMBO J 2001; 20 : 3861–70. [Google Scholar]
  17. Saintigny Y, Lopez BS. Homologous recombination induced by replication inhibition is stimulated by expression of mutant p53. Oncogene 2002; 21 : 488–92. [Google Scholar]
  18. Janz C, Wiesmuller L. Wild-type p53 inhibits replication-associated homologous recombination. Oncogene 2002; 21 : 5929–33. [Google Scholar]
  19. Sengupta S, Linke SP, Pedeux R, et al. BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination. EMBO J 2003; 22 : 1210–22. [Google Scholar]
  20. Dudenhoffer C, Kurth M, Janus F, et al. Dissociation of the recombination control and the sequence-specific transactivation function of p53. Oncogene 1999; 18 : 5773–84. [Google Scholar]
  21. Willers H, McCarthy EE, Wu B, et al. Dissociation of p53-mediated suppression of homologous recombination from G1/S cell cycle checkpoint control. Oncogene 2000; 19 : 632–9. [Google Scholar]
  22. Linke SP, Sengupta S, Khabie N, et al. p53 interacts with hRAD51 and hRAD54, and directly modulates homologous recombination. Cancer Res 2003; 63 : 2596–605. [Google Scholar]
  23. Yoon D, Wang Y, Stapleford K, et al. P53 inhibits strand exchange and replication fork regression promoted by human Rad51. J Mol Biol 2004; 336 : 639–54. [Google Scholar]
  24. Lee S, Cavallo L, Griffith J. Human p53 binds Holliday junctions strongly and facilitates their cleavage. J Biol Chem 1997; 272 : 7532–9. [Google Scholar]
  25. Lee S, Elenbaas B, Levine A, Griffith J. p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches. Cell 1995; 81 : 1013–20. [Google Scholar]
  26. Buchhop S, Gibson MK, Wang XW, et al. Interaction of p53 with the human Rad51 protein. Nucleic Acids Res 1997; 25 : 3868–74. [Google Scholar]
  27. Bertrand P, Saintigny Y, Lopez BS. p53’s double life : transactivation-independent repression of homologous recombination. Trends Genet 2004; 20 : 235–43. [Google Scholar]
  28. Dudenhoffer C, Rohaly G, Will K, et al. Specific mismatch recognition in heteroduplex intermediates by p53 suggests a role in fidelity control of homologous recombination. Mol Cell Biol 1998; 18 : 5332–42. [Google Scholar]
  29. Susse S, Janz C, Janus F, et al. Role of heteroduplex joints in the functional interactions between human Rad51 and wild-type p53. Oncogene 2000; 19 : 4500–12. [Google Scholar]
  30. Degtyareva N, Subramanian D, Griffith JD. Analysis of the binding of p53 to DNAs containing mismatched and bulged bases. J Biol Chem 2001; 276 : 8778–84. [Google Scholar]
  31. Zink D, Mayr C, Janz C, Wiesmuller L. Association of p53 and MSH2 with recombinative repair complexes during S phase. Oncogene 2002; 21 : 4788–800. [Google Scholar]
  32. Subramanian D, Griffith JD. Interactions between p53, hMSH2-hMSH6 and HMG I(Y) on Holliday junctions and bulged bases. Nucleic Acids Res 2002; 30 : 2427–34. [Google Scholar]
  33. Waldman AS, Liskay RM. Dependence of intrachromosomal recombination in mammalian cells on uninterrupted homology. Mol Cell Biol 1988; 8 : 5350–7. [Google Scholar]
  34. Rayssiguier C, Thaler DS, Radman M. The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants. Nature 1989; 342 : 396–401. [Google Scholar]
  35. Jimenez GS, Nister M, Stommel JM, et al. A transactivation-deficient mouse model provides insights into Trp53 regulation and function. Nat Genet 2000; 26 : 37–43. [Google Scholar]
  36. Komarov PG, Komarova EA, Kondratov RV, et al. A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science 1999; 285 : 1733–7. [Google Scholar]
  37. Deng C, Zhang P, Harper JW, et al. Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 1995; 82 : 675–84. [Google Scholar]
  38. Szostak JW, Orr-Weaver TL, Rothstein RJ, Stahl FW. The double-strand-break repair model for recombination. Cell 1983; 33 : 25–35. [Google Scholar]
  39. Rossignol JL. La recombinaison homologue : mécanismes et conséquences. Med Sci (Paris) 1990; 6 : 4–9. [Google Scholar]

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