Free Access
Med Sci (Paris)
Volume 19, Number 1, Janvier 2003
Page(s) 100 - 106
Section M/S Revues – Série Thématique : Trafic Intracellulaire (3)
Published online 15 January 2003
  1. Tortorella D, Gewurz BE, Furman MH, et al. Viral subversion of the immune system. Annu Rev Immunol 2000; 18: 861–926. [Google Scholar]
  2. Janvier K, Petit C, Le Rouzic E, et al. HIV auxiliary proteins: an interface between the virus and the host. AIDS 2000; 14: S21–30. [Google Scholar]
  3. Lama J, Ware CF. Human immunodeficiency virus type 1 Nef mediates sustained membrane expression of tumor necrosis factor and the related cytokine Light on activated T cells. J Virol 2000; 74: 9396–402. [Google Scholar]
  4. Stumptner-Cuvelette P, Morchoisne S, Dugast M, et al. HIV-1 Nef impairs MHC class II antigen presentation and surface expression. Proc Natl Acad Sci USA 2001; 98: 12144–9. [Google Scholar]
  5. Sol-Foulon N, Moris A, Nobile C, et al. HIV-1 Nefinduced upregulation of DCSign in dendritic cells promotes lymphocyte clustering and viral spread. Immunity 2002; 16: 145–55. [Google Scholar]
  6. Le Gall S, Erdtmann L, Benichou S, et al. Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules. Immunity 1998; 8: 483–95. [Google Scholar]
  7. Aiken C, Konner J, Landau NR, et al. Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. Cell 1994; 76: 853–64. [Google Scholar]
  8. Swigut T, Shohdy N, Skowronski J. Mechanism for down-regulation of CD28 by Nef. EMBO J 2001; 20: 1593–604. [Google Scholar]
  9. Bresnahan PA, Yonemoto W, Ferrell S, et al. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor. Curr Biol 1998; 8: 1235–8. [Google Scholar]
  10. Craig HM, Reddy TR, Riggs NL, et al. Interactions of HIV-1 nef with the mu subunits of adaptor protein complexes 1, 2, and 3: role of the dileucine-based sorting motif. Virology 2000; 271: 9–17. [Google Scholar]
  11. Benichou S, Bomsel M, Bodeus M, et al. Physical interaction of the HIV-1 Nef protein with beta-COP, a component of non-clathrincoated vesicles essential for membrane traffic. J Biol Chem 1994; 269: 30073–6. [Google Scholar]
  12. Piguet V, Gu F, Foti M, et al. Nef-induced CD4 degradation: a diacidicbased motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes. Cell 1999; 97: 63–73. [Google Scholar]
  13. Aniento F, Gu F, Parton RG, Gruenberg J. An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes. J Cell Biol 1996; 133: 29–41 [Google Scholar]
  14. Piguet V, Wan L, Borel C, et al. HIV-1 Nef protein binds to the cellular protein PACS- 1 to downregulate class I major histocompatibility complexes. Nat Cell Biol 2000; 2: 163–7. [Google Scholar]
  15. Lu X, Yu H, Liu SH, et al. Interactions between HIV-1, Nef and vacuolar ATPase facilitate the internalization of CD4. Immunity 1998; 8: 647–56. [Google Scholar]
  16. Crump CM, Xiang Y, Thomas L, et al. PACS-1 binding to adaptors is required for acidic cluster motifmediated protein traffic. EMBO J 2001; 20: 2191–201. [Google Scholar]
  17. Geyer M, Fackler OT, Peterlin BM. Structure-function relationships in HIV-1 Nef. EMBO Rep 2001; 2: 580–5. [Google Scholar]
  18. Janvier K, Craig H, Le Gall S, et al. Nef-induced CD4 downregulation: a diacidic sequence in human immunodeficiency virus type 1 Nef does not function as a protein sorting motif through direct binding to beta-COP. J Virol 2001; 75: 3971–6. [Google Scholar]
  19. Doms RW, Trono D. The plasma membrane as a combat zone in the HIV battlefield. Genes Dev 2000; 14: 2677–88. [Google Scholar]
  20. Le Gall S, Buseyne F, Trocha A, et al. Distinct trafficking pathways mediate Nefinduced and clathrindependent major histocompatibility complex class I down-regulation. J Virol 2000; 74: 9256–66. [Google Scholar]
  21. Erdtmann L, Janvier K, Raposo G, et al. Two independent regions of HIV- 1 Nef are required for connection with the endocytic pathway through binding to the mu 1 chain of AP1 complex. Traffic 2000; 1: 871–83. [Google Scholar]
  22. Sanfridson A, Hester S, Doyle C. Nef proteins encoded by human and simian immunodeficiency viruses induce the accumulation of endosomes and lysosomes in human T cells. Proc Natl Acad Sci USA 1997; 94: 873–8. [Google Scholar]
  23. Choi J, Means RE, Damania B, et al. Molecular piracy of Kaposi’s sarcoma associated herpesvirus. Cytokine Growth Factor Rev 2001; 12: 245–57. [Google Scholar]
  24. Coscoy L, Ganem D. Kaposi’s sarcoma-associated herpesvirus encodes two proteins that block cell surface display of MHC class I chains by enhancing their endocytosis. Proc Natl Acad Sci USA 2000; 97: 8051–6. [Google Scholar]
  25. Ishido S, Wang C, Lee BS, et al. Downregulation of major histocompatibility complex class I molecules by Kaposi’s sarcoma-associated herpesvirus K3 and K5 proteins. J Virol 2000; 74: 5300–9. [Google Scholar]
  26. Coscoy L, Ganem D. A viral protein that selectively downregulates ICAM-1 and B7-2 and modulates T cell costimulation. J Clin Invest 2001; 107: 1599–606. [Google Scholar]
  27. Ishido S, Choi JK, Lee BS, et al. Inhibition of natural killer cell-mediated cytotoxicity by Kaposi’s sarcoma-associated herpesvirus K5 protein. Immunity 2000; 13: 365–74. [Google Scholar]
  28. Coscoy L, Sanchez DJ, Ganem D. A novel class of herpesvirus-encoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition. J Cell Biol 2001; 155: 1265–73. [Google Scholar]
  29. Hewitt EW, Duncan L, Mufti D, Baker J, Stevenson PG, Lehner PJ. Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101- dependent degradation. EMBO J 2002; 21: 2418–29. [Google Scholar]
  30. Hicke L. Protein regulation by monoubiquitin. Nat Rev Mol Cell Biol 2001; 2: 195–201. [Google Scholar]
  31. Conibear E. An ESCRT into the endosome. Mol Cell 2002; 10: 215–6. [Google Scholar]
  32. Boname JM, Stevenson PG. MHC class I ubiquitination by a viral PHD/LAP finger protein. Immunity 2001; 15: 627–36. [Google Scholar]
  33. Tollefson AE, Hermiston TW, Lichtenstein DL, et al. Forced degradation of Fas inhibits apoptosis in adenovirus-infected cells. Nature 1998; 392: 726–30. [Google Scholar]
  34. Tollefson AE, Toth K, Doronin K, et al. Inhibition of Trailinduced apoptosis and forced internalization of Trail receptor 1 by adenovirus proteins. J Virol 2001; 75: 8875–87. [Google Scholar]
  35. Carlin CR, Tollefson AE, Brady HA, et al. Epidermal growth factor receptor is down-regulated by a 10,400 MW protein encoded by the E3 region of adenovirus. Cell 1989; 57: 135–44. [Google Scholar]

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