Open Access
Tableau I.
Molécules inhibitrices des points de contrôle immunitaire et leurs cibles.
| Molécule | Isotype | Cible |
|---|---|---|
| Nivolumab (Opdivo®) | IgG4 | PD-1 |
| Pembrolizumab (Keytruda®) | IgG4 | PD-1 |
| Cémiplimab (Libtayo®) | IgG4 | PD-1 |
| Atézolizumab (Tecentriq®) | IgG1 | PD-L1 |
| Durvalumab (Imfinzi®) | IgG1 | PD-L1 |
| Avélumab (Bavencio®) | IgG1 | PD-L1 |
| Ipilimumab (Yervoy®) | IgG1 | CTLA-4 |
| Trémélimumab | IgG2 | CTLA-4 |
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