Figure 2.
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De nombreux récepteurs activateurs et inhibiteurs régulent la réponse des lymphocytes T. PD-1: programmed cell death protein 1 ; CTLA-4: cytolytic T-lymphocyte-associated protein 4 ; LAG-3: lymphocyte activation gene 3 ; TIM-3: T cell immunoglobulin and mucin domain-containing-3 ; TIGIT: T-cell immunoreceptor with Ig and ITIM domains ; ICOS: inducible T-cell costimulatory ; GITR: glucocorticoid-induced tumor necrosis factor-related protein ; TCR: - cell receptor ; CMH: complexe majeur d’histocompatibilité ; FLP-1: fibrinogen-like protein 1 ; GAL9: galectine 9 ; PS: phosphatidylsérine ; CEA-CAM1: carcinoembryonic antigen-related cell adhesion molecule 1 ; L: ligand.
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