SLC25A15 knockdown inhibits the proliferation of A375 cells. A. Relative expression levels of SLC25A15 in A375 cells after treatment with small interfering RNA (q-PCR). B-C. Relative protein expression levels of ORC1 in A375 cells after treatment with small interfering RNA (Western blot). D. SLC25A15 knockdown decreases the viability of A375 cells as shown by a CCK8 assay. E-F. SLC25A15 knockdown inhibits colony formation of A375 cells in a colony formation assay. All values are presented as means ± S.D. * P<0.05, ** P<0.01 compared with si-con group. n=5 for each group. si-con, scramble control siRNA.