Tableau II.
Exemples de lncRNA associés à des pathologies. BACE1-as : β-amyloid converting enzyme 1-antisense ; DBE-T : D4Z4 binding element transcript ; CDKN2B-as1 : (ANRIL), un lncRNA impliqué dans divers cancers ; MVIH : microvascular invasion ; HOTAIR : Hox antisense intergenic RNA ; HULC : highly up-regulated in liver cancer ; PCA3 : prostate cancer antigen 3 ; MALAT1 : metastasis associated lung adenocarcinoma transcript 1.
| Noms | Pathologies | Réf. |
|---|---|---|
| CDKN2B-as1 | Artériosclérose, risques cardiovasculaires, divers cancers | [33–35] |
| BACE1-as | Alzheimer | [40] |
| DBE-T | Dystrophie facio-scapulo-humérale | [41] |
| MVIH | Carcinome hépatique | [30] |
| HOTAIR | Cancer du sein, cancer colorectal | [25, 26] |
| HULC | Cancer du foie | [27] |
| lncRNA HYMAI | Diabète néonatal transitoire | [42] |
| PCA3 | Cancer de la prostate | [28] |
| LincRNA-p21 | Sarcome, lymphome, cancer du poumon | [31] |
| MALAT1 | Cancer du poumon, de l’utérus, du sein, du pancréas, du rein, du côlon et de la prostate | [43-45] |
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