Free Access
Tableau II
Liste non exhaustive de miARN circulants associés à diverses pathologies ou conditions biologiques.
| miARN | Expression | Organisme | Maladie/condition biologique | Plasma/Sérum |
|---|---|---|---|---|
| Cancer | ||||
| miR-16, 92a, 103, 107, 197, 34b, 328, 485-3p, 486-5p, 92b, 574-3p, 636, 640, 766, 885-5p, 141, 375 | Augmentation | Homme | Cancer de la prostate | Plasma/sérum |
| miR-155, 210, 21 | Augmentation | Homme | Lymphome diffus à grandes cellules B (DLBCL) | Sérum |
| miR-92a, 638 | Diminution | Homme | Leucémie aiguë myéloïde (AML) | Plasma |
| miR-21, 210, 155, 196a, 200a, 200b | Augmentation | Homme | Cancer du pancréas | Plasma/sérum |
| miR-195, let-7a, 155, 10b, 34a, 21 | Augmentation | Homme | Cancer du sein | Plasma/sérum |
| miR-21, 92, 93 | Augmentation | Homme | Cancer de l’ovaire | Sérum |
| miR-29a, 92 | Augmentation | Homme | Cancer colorectal | Plasma |
| miR-1, 20a, 27a, 34, 423-5p, 17-5p, 21, 106a, 106b, let-7a | Augmentation/diminution | Homme | Cancer gastrique | Plasma/sérum |
| miR-184 | Augmentation | Homme | Carcinome à cellules squameuses (SCC) | Plasma |
| miR-24, 31 | Augmentation | Homme | Carcinome buccal à cellules squameuses (OSCC) | Plasma |
| miR-21, 375, 10a, 22, 100, 148b, 223, 133a, 127-3p | Augmentation/diminution | Homme | Cancer de l’œsophage (ESCC) | Plasma/sérum |
| miR-486, 30d, 499, 1, 21, 141, 200c, 1254, 574-5p | Augmentation/diminution | Homme | Non-small cell lung cancer (NSCLC) | Plasma/sérum |
| miR-221 | Augmentation | Homme | Mélanome | Sérum |
| Atteinte cardiaque | ||||
| miR-208a | Augmentation | Homme/rat | Lésion du myocarde | Plasma |
| miR-1, 133a, 133b, 499-5p | Augmentation | Homme/ | ||
| souris/rat | Infarctus du myocarde (AMI) | Plasma/sérum | ||
| miR-122, 375 | Diminution | Homme | Infarctus du myocarde avec surélévation du segment ST (STEMI) | Plasma |
| miR-423-5p | Augmentation | Homme | Infarctus du myocarde | Plasma |
| Foie/atteinte tissulaire | ||||
| miR-122, 192 | Augmentation | Souris | Lésions hépatiques toxiques médicamenteuses | Sérum |
| miR-122, 133a, 124 | Augmentation | Rat | Atteinte tissulaire | Plasma |
| Infection | ||||
| miR-150, 146a, 223 | Diminution | Homme | Sepsis | Plasma/sérum |
| Grossesse | ||||
| miR-520d-5p, 526a, 527 | Augmentation | Homme | Grossesse | Sérum |
| Maladie psychiatrique | ||||
| miR-134 | Diminution | Homme | Trouble bipolaire | Plasma |
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