Tableau III.
Virus activateurs des inflammasomes. *Les rôles directs de RIG-I et IFI16 en tant qu’activateurs de l’inflammasome restent à confirmer. CLEC5A : C-type lectin 5A ; VIH : virus de l’immunodéficience humaine ; db : double brin ; sb : simple brin.
| Inflammasomes | Virus | ARN/ADN | Motifs activateurs |
|---|---|---|---|
| NLRP3 | Virus de la rougeole | ARN | ? |
| Virus de l’hépatite C | ARN | ? | |
| Virus influenza | ARN | Insertion de M2 | |
| Virus respiratoire syncitial | ARN | ROS/efflux de K+ | |
| Virus de la dengue | ARN | CLEC5A | |
| MVA | ADN | ? | |
| Myxoma virus | ADN | Cathepsine B/ROS | |
| Virus varicelle-zona | ADN | ? | |
| Herpes simplex 1 | ADN | ? | |
| VIH 1 | ADN | ? | |
| IFI16* | Herpes simplex 1 | ADN | ADNdb ? |
| KSHV | ADN | ADNdb ? | |
| Cytomégalovirus | ADN | ADNdb ? | |
| RIG-I* | ? | ARN? | ARNsb? |
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