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Tableau II.

Bactéries activatrices des différents inflammasomes et motifs activateurs. ESX-1 : ESAT-6 secretion system 1 ; ESAT-6 : 6-kDa early secreted antigenic target ; YopJ : Yersinia outer protein J ; Mxil : Max-interactor 1.

Inflammasomes Bactéries Motifs activateurs Références
NLRP1 Bacillus anthracis Toxine létale [35, 36]
NLRP3 Burkholderia pseudomallei BsaK
Chlamydia pneumoniae ?
Escherichia coli ARNm [22]
Streptococcus B Hémolysine β [23]
Listeria monocytogenes Lystériolysine O
Mycobacterium tuberculosis ESX-1, ESAT-6
Staphylococcus aureus Hémolysine α [22]
Streptococcus pneumoniae Pneumolysine
Vibrio cholera Toxine cholérique B
Yersinia pestis Système de sécrétion de type 3, YopJ
Neisseria gonorrhoeae ?
Treponema  denticola Td92
Leptospira interrogans Glycolipoprotéine
NLRP7 Mycoplasma spp Lipopeptide acylé
NLRP12 Yersinia pestis ? [40]
NLRC4 Burkholderia pseudomallei BsaK
Escherichia coli EprJ, EscI
Legionella pneumophila Flagelline [27, 33]
Pseudomonas aeruginosa Flagelline, PscL
Salmonella typhimurium Système de sécrétion de type 3, flagelline, PrgJ
Shigella flexneri Mxil
Yersinia pestis Système de sécrétion de type 3
AIM2 Francisella tularensis ADN [41]
Listeria monocytogenes ADN
Mycobacterium tuberculosis ADN

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