Figure 2.
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Structure des protéines CARMA1, BCL-10 et MALT1. CARMA1 est un membre de la famille MAGUK (membrane-associated guanylate kinase) et contient un domaine CARD (caspase recruitment domain), un domaine Coiled-Coil (CC), un domaine PDZ (Psd95, Dlga and Zo1 homology), un domaine SH3 (Src-Homology 3) et un domaine GUK (guanylate kinase). BCL-10 (B-cell lymphoma-10) contient un domaine CARD et un domaine riche en sérines et thréonines. MALT1 contient un death domain (DD), deux domaines Ig like et un domaine caspase like.
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