| Issue |
Med Sci (Paris)
Volume 39, Number 4, Avril 2023
|
|
|---|---|---|
| Page(s) | 381 - 383 | |
| Section | Forum | |
| DOI | https://doi.org/10.1051/medsci/2023049 | |
| Published online | 24 April 2023 | |
Les traces génétiques de la peste noire
Chroniques génomiques
Genetic legacy of the Black Death pandemic
Biologiste, généticien et immunologiste, président d’Aprogène (Association pour la promotion de la Génomique), 13007 Marseille, France
Abstract
Genetic analysis of human populations before and after the great plague pandemic in the late Middle Ages reveals immune-related loci at which specific alleles have been selected because they conferred (partial) resistance to the pathogen. Some of these alleles are associated with susceptibility to present-day immune diseases, illustrating the complex interplay between genes, environment and the immune system.
© 2023 médecine/sciences – Inserm
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