| Issue |
Med Sci (Paris)
Volume 39, Number 1, Janvier 2023
|
|
|---|---|---|
| Page(s) | 83 - 86 | |
| Section | Forum | |
| DOI | https://doi.org/10.1051/medsci/2022187 | |
| Published online | 24 January 2023 | |
Taille à l’âge adulte : une myriade de locus
Chroniques génomiques
Multiple loci account for human height
Biologiste, généticien et immunologiste, Président d’Aprogène (Association pour la promotion de la Génomique), 13007 Marseille, France
Abstract
The combination of 281 GWAS studies for adult height leads to the identification of 12,111 SNP in 7,209 loci that together account for essentially all SNP heritability for this trait: there is no longer any significant “missing heritability”, and these loci appear to be functionally relevant. This work is a model for future studies on the genetic determinants of complex diseases.
© 2023 médecine/sciences – Inserm
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