Open Access
Issue
Med Sci (Paris)
Volume 41, Number 11, Novembre 2025
Page(s) 900 - 908
Section Repères
DOI https://doi.org/10.1051/medsci/2025161
Published online 12 décembre 2025
  1. Fischer KL, Jaffredo M, Lang J, Raoux M. Cellules α et β du pancréas: meilleures ennemies ou partenaires pour la vie ?. Med Sci (Paris) 2021; 37 : 752–8. [Google Scholar]
  2. Vantyghem MC, de Koning EJP, Pattou F, Rickels MR. Advances in beta-cell replacement therapy for the treatment of type 1 diabetes. Lancet 2019; 394 : 1274–85. [Google Scholar]
  3. Shapiro AM, Lakey JR, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. The New Engl JMed 2000; 343 : 230–8. [Google Scholar]
  4. Marfil-Garza BA, Hefler J, Verhoeff K, et al. Pancreas and islet transplantation: comparative outcome analysis of a single-centre cohort over 20-years. Ann Surg 2023; 277 : 672–80. [Google Scholar]
  5. Lablanche S, Vantyghem MC, Kessler L, et al. Islet transplantation versus insulin therapy in patients with type 1 diabetes with severe hypoglycaemia or poorly controlled glycaemia after kidney transplantation (TRIMECO): a multicentre, randomised controlled trial. Lancet Diabetes Endocrinol 2018; 6 : 527–37. [CrossRef] [PubMed] [Google Scholar]
  6. Rickels MR, Robertson RP. Pancreatic islet transplantation in humans: recent progress and future directions. Endocr Rev 2019; 40 : 631–68. [Google Scholar]
  7. Hubert T, Arnalsteen L, Jany T, et al. Technique of pancreatic procurement for pancreatic islet isolation. Ann Chir 2005; 130 : 384–90. [Google Scholar]
  8. Maglio M, Goudot FX. Le prélèvement d’organes de type Maastricht 3 — Du discours bioéthique au langage ordinaire. Med Sci (Paris) 2023; 39 : 975–80. [Google Scholar]
  9. Hubert T, Gmyr V, Arnalsteen L, et al. Influence of preservation solution on human islet isolation outcome. Transplantation 2007; 83 : 270–6. [Google Scholar]
  10. Kerr-Conte J, Vandewalle B, Moerman E, et al. Upgrading pretransplant human islet culture technology requires human serum combined with media renewal. Transplantation 2010; 89 : 1154–60. [Google Scholar]
  11. Pasquetti GT, J. Chetboun, M. Apete, et al. In vivo quality control of human islets in the immunodeficient mouse to predict islet function in man: a retrospective study in 87 clinical transplants. In : Elsevier, ed. Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas 2019; 711–724. [Google Scholar]
  12. Caiazzo R, Vantyghem MC, Raverdi V, et al. Impact of procedure-related complications on long-term islet transplantation outcome. Transplantation 2015; 99 : 979–84. [Google Scholar]
  13. Vantyghem MC, Chetboun M, Gmyr V, et al. Ten-year outcome of islet alone or islet after kidney transplantation in type 1 diabetes: a prospective parallel-arm cohort study. Diabetes Care 2019; 42 : 2042–9. [Google Scholar]
  14. Mailliez A, Ternynck C, Jannin A, et al. Cognitive outcome after islet transplantation. Transplant Direct 2023; 9 : e1493. [Google Scholar]
  15. Maanaoui M, Lenain R, Foucher Y, et al. Islet-after-kidney transplantation versus kidney alone in kidney transplant recipients with type 1 diabetes (KAIAK): a population-based target trial emulation in France. Lancet Diabetes Endocrinol 2024; 12 : 716–24. [Google Scholar]
  16. Isenberg JS, Kandeel F. Can islet transplantation possibly reduce mortality in type 1 diabetes. Cell Transplant 2025; 34 : 9636897241312801. [Google Scholar]
  17. Perrier Q, Jambon-Barbara C, Kessler L, et al. Impact of islet transplantation on diabetes complications and mortality in patients living with type 1 diabetes. Diabetes Care 2025; 48 : 1007–15. [Google Scholar]
  18. Marfil-Garza BA, Imes S, Verhoeff K, et al. Pancreatic islet transplantation in type 1 diabetes: 20-year experience from a single-centre cohort in Canada. Lancet Diabetes Endocrinol 2022; 10 : 519–32. [Google Scholar]
  19. Catarinella D, Melzi R, Mercalli A, et al. Long-term outcomes of pancreatic islet transplantation alone in type 1 diabetes: a 20-year single-centre study in Italy. Lancet Diabetes Endocrinol 2025; 13 : 279–93. [Google Scholar]
  20. Ryan EA, Paty BW, Senior PA, et al. Beta-score: an assessment of beta-cell function after islet transplantation. Diabetes Care 2005; 28 : 343–7. [Google Scholar]
  21. Chetboun M LMK, Gmyr V et al. Optimizing primary graft function in islet allotransplantation: The Lille experience. In: Transplantation, Bioengineering, and Regeneration of the Endocrine pancreas : Academic Press, 2020 : 637–43. [Google Scholar]
  22. Chetboun M, Drumez E, Ballou C, et al. Association between primary graft function and 5-year outcomes of islet allogeneic transplantation in type 1 diabetes: a retrospective, multicentre, observational cohort study in 1210 patients from the Collaborative Islet Transplant Registry. Lancet Diabetes Endocrinol 2023; 11 : 391–401. [Google Scholar]
  23. Guignard AP, Oberholzer J, Benhamou PY, et al. Cost analysis of human islet transplantation for the treatment of type 1 diabetes in the Swiss-French Consortium GRAGIL. Diabetes Care 2004; 27 : 895–900. [Google Scholar]
  24. Chinnakotla S, Beilman GJ, Vock D, et al. Intraportal Islet Autotransplantation independently improves quality of life after total pancreatectomy in patients with chronic refractory pancreatitis. Ann Surg 2022; 276 : 441–9. [Google Scholar]
  25. Piemonti L, Melzi R, Aleotti F, et al. Autologous pancreatic islet cell transplantation following pancreatectomy for pancreas diseases other than chronic pancreatitis: a 15-y study of the milan protocol. Transplantation 2024; 108 : 1962–75. [Google Scholar]
  26. Vieira A, Druelle N, Courtney M, et al. Reprogrammation des cellules pancréatiques en cellules β. Med Sci (Paris) 2013; 29 : 749–55. [Google Scholar]
  27. Balboa D, Barsby T, Lithovius V, et al. Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells. Nature Biotechnol 2022; 40 : 1042–55. [Google Scholar]
  28. Wang S, Du Y, Zhang B, et al. Transplantation of chemically induced pluripotent stem-cell-derived islets under abdominal anterior rectus sheath in a type 1 diabetes patient. Cell 2024; 187 : 6152-64 e18. [Google Scholar]
  29. Matsumoto S, Matsumoto K. Clinical islet xenotransplantation: development of isolation protocol, anti-rejection strategies, and clinical outcomes. Cells 2024; 13. [Google Scholar]
  30. Piemonti L, Citro A, Tomajer V, et al. Pig xenotransplantation in beta cell replacement: addressing challenges and harnessing potential for type 1 diabetes therapy. Transpl Int 2024; 37 : 13122. [Google Scholar]
  31. Mallapaty S, Kozlov M. The science behind the first pig-organ transplant trial in humans. Nature 2025; 638 : 303–4. [Google Scholar]
  32. Reichman TW, Markmann JF, Odorico J, et al. Stem Cell-Derived, Fully Differentiated Islets for Type 1 Diabetes. N Engl JMed 2025 Jun 20. [Google Scholar]
  33. Berney T, Bellini MI, Montserrat N, et al. Reflecting on an intense year for transplant international. Transpl Int 2022; 35 : 11118. [Google Scholar]
  34. Wang Y, Peng F, Yang Z, et al. A rapid chemical reprogramming system to generate human pluripotent stem cells. Nat Chem Biol 2025. [Google Scholar]
  35. Scheiner ZS, Talib S, Feigal EG. The potential for immunogenicity of autologous induced pluripotent stem cell-derived therapies. J Biol Chem 2014; 289 : 4571–7. [Google Scholar]
  36. Strand BL, Coron AE, Skjak-Braek G. Current and Future Perspectives on Alginate Encapsulated Pancreatic Islet. Stem Cells Transl Med 2017; 6 : 1053–8. [Google Scholar]
  37. Cooper-Jones B, Ford C. CADTH horizon scans islet replacement therapy for insuilin-dependent diabetes. In: CADTH Issues in Emerging Health Technologies. Ottawa (ON) 2016 : 1–9. [Google Scholar]
  38. Desai T, Shea LD. Advances in islet encapsulation technologies. Nat Rev Drug Discov 2017; 16 : 338–50. [Google Scholar]

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